New Funding Awards August 2024

Sponsored Research

Adrian Hernandez of Cardiology has received an award from the Food and Drug Administration for a project entitled "FDA IPA - Suresh Balu." Total funding will be $47,161.

William Jones of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet CC - Scope 6 - Playbook." Total funding will be $446,880.

Lauren E. Parker (Mentor: Ravi Karra) of Cardiology has received an award (1F30-HL175908-01) from the National Institutes of Health for a project entitled "Myovascular interactions stimulate cardiac regeneration in self-assembling cardiac organoids." Total funding will be $150,445.

Sean Pokorney of Cardiology has received a sub-award () through the University of North Carolina - Chapel Hill for a project entitled "Improving Outpatient Comprehensive Atrial Fibrillation Care Across Central North Carolina Through Direct Primary Care Engagement." Total funding will be $38,371.

Jie Wang of Cell Therapy has received a sub-award (5R01-CA265929-03) through the Hoosier Cancer Research Network, Inc for a project entitled "HCRN-LYM21-544." Total funding TBD.

Jessica Cannavino of Endocrinology has received a sub-award () through the Wake Forest University School Of Medicine for a project entitled "NCDRC Pilot: Molecular Mechanisms Coupling Healthy Adipose Tissue Remodeling to Preserved Insulin Sensitivity in Obesity." Total funding will be $50,000.

Annelise M. Poss (Mentor: Deborah Muoio) of Endocrinology has received an award (1F32-HL176113-01) from the National Institutes of Health for a project entitled "Mitochondrial succinyl CoA management at the intersection of heme and ketone metabolism." Total funding will be $221,520.

Guofang Zhang of Endocrinology has received an award (1R21-TR005163-01) from the National Institutes of Health for a project entitled "Triacetin Treatment for Propionic Acidemia by Rebalancing the Acetyl-CoA/Propionyl-CoA Metabolism." Total funding will be $430,765.

Ayako Suzuki of Gastroenterology has received an award (2U01-DK061713-23) from the National Institutes of Health for a project entitled "Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)." Total funding will be $750,002.

Rowena Dolor of General Internal Medicine has received a sub-award () through the Dartnet Institute for a project entitled "ADA DARTNet Institute Alliance for Diabetes (ADA DIAD)." Total funding will be $27,500.

Lori Orlando of General Internal Medicine has received an award (3U01-HG010231-05S3) from the National Institutes of Health for a project entitled "IGNITE Cost Extension- Year 7." Total funding will be $345,120.

Michael Pignone of General Internal Medicine has received a sub-award (CSDG-21-042-01-CPHPS) through the University of Texas at Austin for a project entitled "Optimizing Care Delivery and Health Equity in Patients With Melanoma." Total funding will be $19,801.

Grace Lee of Hematology has received an award (1R01-HL174452-01) from the National Institutes of Health for a project entitled "RBC Effects on Neutrophil Activation and Phenotypes in Sickle Cell Disease." Total funding will be $3,145,459.

Oluwatoyosi Onwuemene of Hematology has received an award (1R21-TR004694-01A1) from the National Institutes of Health for a project entitled "A Clinical Trial Readiness Study of Patient Reported Outcome Measures in Thrombotic Thrombocytopenic Purpura (TTP)." Total funding will be $456,348.

Thuy Le of Infectious Diseases has received an award (1R01-AI181764-01A1) from the National Institutes of Health for a project entitled "Liposomal Amphotericin B and Flucytosine Antifungal Strategies for Talaromycosis (LAmB-FAST) - R01." Total funding will be $6,322,062.

Nicholas DeVito of Oncology has received an award from the Gateway for Cancer Research for a project entitled "Botensilimab and Balstilimab Optimization in Colorectal cancer (BBOpCo)." Total funding will be $279,936.

Christopher Cox of Pulmonary has received an award (1R01-AG084572-01A1) from the National Institutes of Health for a project entitled "Improving needs among older adults: the ICUconnect 2 primary palliative care RCT." Total funding will be $3,327,150.

Brian Andonian of Rheumatology has received an award (1K23-AG080066-01A1) from the National Institutes of Health for a project entitled "The Effect of Exercise on T Cell Aging in Rheumatoid Arthritis." Total funding will be $800,254.



Industry Sponsored Clinical Trials

James Daubert of Cardiology has received an award from Rocket Pharmaceuticals, Ltd for a project entitled "PKP2 Dose Escalation Trial of RP-A601." Total funding will be $955,551.

Melissa Daubert of Cardiology has received an award from VisCardia, Inc. for a project entitled "RECOVER-HF." Total funding will be $387,903.

Stephen Greene of Cardiology has received an award from Novo Nordisk, Inc. for a project entitled "NOVN - NovoInfBmkrs_DS - Industry." Total funding will be $51,984.

Michel Khouri of Cardiology has received an award from Alexion Pharmaceuticals, Inc. for a project entitled "DepleTTR-CM." Total funding will be $1,664,074.

Jonathan Piccini of Cardiology has received an award from American Heart Association for a project entitled "GWTG Inpatient Data Analysis Center." Total funding will be $1,640,880.

Jonathan Piccini of Cardiology has received an award from Boston Scientific Corporation for a project entitled "A Prospective Randomized Multicenter Global Study Comparing Pulsed Field Ablation versus Anti-Arrhythmic Drug Therapy as a First Line Treatment for Persistent Atrial Fibrillation." Total funding will be $190,293.

Jennifer Rymer of Cardiology has received an award from American College of Cardiology for a project entitled "Cath-PCI Registry." Total funding will be $440,847.

Nishant Shah of Cardiology has received an award from Amgen, Inc. for a project entitled "Test to Treat: A Randomized Implementation Trial to Improve LDL-C Management after Hospitalization for ASCVD." Total funding will be $184,742.

Sanghee Hong of Cell Therapy has received an award from Cullinan Florentine Corporation for a project entitled "A Phase 1, Open-label, Preliminary Pharmacokinetics (PK) and Safety Study of CLN-049 (An fms-like tyrosine kinase 3 [FLT3] x cluster of differentiation 3 [CD3] bispecific T cell engager) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (A." Total funding will be $484,085.

Yubin Kang of Cell Therapy has received an award from Janssen Research & Development, LLC for a project entitled "A Phase 2, Open-label, Randomized Study to Evaluate Prophylactic Interventions on Talquetamab-related Oral Toxicity." Total funding will be $478,520.

Thomas Leblanc of Cell Therapy has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "Early Stage Lung Cancer Patient Identification, Time to Treatment Initiation, and Potential Patient Distress." Total funding will be $240,413.

Lindsay Rein of Cell Therapy has received an award from Karyopharm Therapeutics for a project entitled "A Phase 2 study to evaluate the efficacy and safety of selinexor monotherapy in subjects with JAK inhibitor-naive myelofibrosis and moderate thrombocytopenia." Total funding will be $394,044.

William Yancy of General Internal Medicine has received an award from Shionogi Inc. for a project entitled "A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of S-217622 in the prevention of symptomatic SARS-C0V-2 infection in household contacts of an individual with symptomatic COVID-19." Total funding will be $25,701.

Barbara Alexander of Infectious Diseases has received an award from F2G Ltd for a project entitled "A Multi-center, Retrospective Review of Invasive Aspergillosis Cases." Total funding will be $246,807.

Andrew Armstrong of Oncology has received a sub-award (5R44-CA278187-02) through Syntrix Biosystems, Inc. for a project entitled "SX-682 + Enzalutamide in Abiraterone-Resistant mCRPC." Total funding TBD.

Rani Bansal of Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase III, Open-label, Randomised Study of Neoadjuvant Datopotamab Deruxtecan (Dato-DXd) Plus Durvalumab Followed by Adjuvant Durvalumab With or Without Chemotherapy Versus Neoadjuvant Pembrolizumab Plus Chemotherapy Followed by Adjuvant Pembroliz." Total funding will be $719,743.

Nicholas DeVito of Oncology has received an award from Xilio Development Inc. for a project entitled "A First-in-Human, Multicenter, Phase 1/2, Open-Label Study of Vilastobart (XTX101) Monotherapy and Vilastobart (XTX101) and Atezolizumab Combination Therapy in Patients with Advanced Solid Tumors." Total funding will be $422,307.

Niharika Mettu of Oncology has received an award from Numab Therapeutics AG for a project entitled "A Phase 1 Study of NM32-2668 (Anti-ROR1/Anti-CD3/Anti-HSA Tri-Specific Antibody) in Adult Patients with Selected Advanced Solid Tumors." Total funding will be $971,180.

Neal Ready of Oncology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "Safety, Efficacy, and Tumor Immune Microenvironment Changes with Neoadjuvant Chemotherapy and Cemiplimab with or without Alirocumab in Stage 1B-3A Non-Small Cell Lung Cancer." Total funding will be $2,567,451.

Richard Riedel of Oncology has received an award from Servier Bio-Innovation, LLC for a project entitled "A Phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib in participants ?18 years of age with locally advanced or metastatic conventional chondrosarcoma with an IDH1 mutation, untreated or previously treated with 1." Total funding will be $331,770.

Matthew Foster of Pulmonary has received an award from Ten63 Therapeutics Inc. for a project entitled "Ten63 Therapeutics SRA." Total funding will be $60,522.

Aparna Swaminathan of Pulmonary has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "SEVERE COUGH A Phase IIa/IIb, randomized, double blind, placebo-controlled, parallel-group dose-finding study to examine the efficacy and safety of BI 1839100 administered orally over a 12-week treatment period in patients with idiopathic pulmonary f." Total funding will be $163,107.
 

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