New funding awards - December 2013

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Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards. [tabs style="vertical"][tab title="Sponsored research"]Melvin R. Echols of Cardiology has received an award (5UO1-HL054904-07) from the National Institutes of Health for a project entitled "Functional Impact of GLP-1 for Heart Failure Treatment - Lumberton." Adrian F. Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research." Total funding will be $2,023,093. Mitchell W. Krucoff of Cardiology has received an award (1U01-FD004964-01) from the Food and Drug Administration for a project entitled "Advancing Medical Device Postmarket Surveillance Infrastructure and Epidemiologic Methodologies through Multi-stakeholder Partnership (U01)." Total funding will be $3,840,851. Gillian D. Schmidler of Cardiology has received a sub-award (PCORI ESG) through the Patient-Centered Outcomes Research Institute for a project entitled "PCORI_Triage and FR Prioritization - Amendment #3." Total funding will be $169,411. Chris Woods of Infectious Diseases has received an award from the National University of Singapore for a project entitled "An Innovative Model for Detecting Interspecies Disease Transmission and Novel Pathogen Detection at Lola Ya Bonobo Sanctuary, Democratic Republic of Congo." Total funding will be $100,000. Andrew Armstrong of Medical Oncology has received an award from the Memorial Sloan-Kettering Cancer Center for a project entitled "TAX 3503, A prospective registry -A Randomized, Open label, Muiticenter, Phase III, 2 Arm Study of Androgen Deprivation with Leuprilode +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Subjects with a Rising PSA Following D. local therapy." Total funding will be $17,200. Kimberly L. Blackwell of Medical Oncology has received an award through Washington University for a project entitled "A Phase II Study of Neratinib in Metastatic HER2 Non-amplified by HER2 Mutant Breast Cancer." Total funding will be $34,000. Gerard C. Blobe of Medical Oncology has received an award from Alex's Lemonade Stand for a project entitled "Stroma Biology Identifies Heparin as a Differentiating Agent in Neuroblastoma." Total funding will be $250,000. Michael R. Harrison of Medical Oncology has received an award from the Memorial Sloan-Kettering Cancer Center for a project entitled "A Phase 2, Randomized, 3-Arm Study of Abiraterone Acetate alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix alone for Patients with Prostate Cancer with a Rise PSA or a Rising PSA and Nodal Disease Following Definitive." Total funding will be $278,292. Lesley H. Curtis of Other Medicine has received a sub-award (N01-HC-25195) through Boston University for a project entitled "Framingham Study - 06 Contract Year." Total funding will be $3,676.[/tab][tab title="Industry-sponsored clinical trials"]Gary M. Felker of Cardiology has received an award from Medtronic, Inc. for a project entitled "Promotion of Renal Sodium Excretion by Renal Sympathetic Denervation in Congestive Heart Failure." Adrian F. Hernandez of Cardiology has received an award from Merck for a project entitled "Merck GWTG CAD." Total funding will be $182,194. William E. Kraus of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Effects of Ranolazine plus Exercise on Stable Angina and Daily Physical Activity." Total funding will be $457,402. Renato D. Lopes of Cardiology has received an award from GlaxoSmithKline for a project entitled "Clinical Events Classification for Bupropion Program." Total funding will be $225,905. Robert J. Noveck of Cardiology has received an award from Acorda Therapeutics, Inc for a project entitled "A Double-Blind Pharacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients with Heart Failure." Total funding will be $194,570. Sreekanth Vemulapalli of Cardiology has received an award from Boston Scientific Corporation for a project entitled "Resistant Hypertension and Stage A/B Heart Failure: Prevalance and Outcomes." Total funding will be $75,000. Andrew J. Muir of Gastroenterology has received an award from Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "BMS AI443-102-0016 A Phase 3 Evaluation." Total funding will be $89,812. Andrew J. Muir of Gastroenterology has received an award from Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "BMS Muir, AI443-113." Total funding will be $89,812. Hans L. Tillmann of Gastroenterology has received an award from Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "Pilot Study to Assess Changes in Immuneregulation with Phase of Chronic HBV Infection and Antiviral Therapy." Total funding will be $37,279. Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "Phase 3 Open-Label Stdy to Eval Switch Opt Stable Antiretro Reg Cont Darunavir to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) plus Darunavir (DRV) in Treatment Experienced HIV-1 Positive Adults." Total funding will be $115,301. Cameron R. Wolfe of Infectious Diseases has received an award through Social & Scientific Systems, Inc. for a project entitled "Task Order CRB-SSS-S-13-003314 - Protocol IRC 003." Total funding will be $105,668. Cameron R. Wolfe of Infectious Diseases has received an award through Social & Scientific Systems, Inc. for a project entitled "Task Order CRB-SSS-S-13-003283 - Protocol IRC004." Total funding will be $63,458. Chris Woods of Infectious Diseases has received an award from Roche Molecular Systems for a project entitled "COB-MRSA-279." Total funding will be $197,669. Frank R. Dunphy II of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A multicenter, open-label, randomized phase II study to evaluate the efficacy of AUY922 vs pemetrexed or docetaxel in NSCLC patients with EGFR mutations who have progressed on prior EGFR TKI treatment." Total funding will be $532,070. Bradford R. Hirsch of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "BMS Visualization Proposal involving BRIDGE Data." Total funding will be $73,200. Michael J. Kelley of Medical Oncology has received an award from the Institute for Medical Research, Inc. for a project entitled "Deborah Iden PSA." Total funding will be $42,685. Fatima A. Rangwala of Medical Oncology has received an award from Onyx Pharmaceuticals, Inc for a project entitled "An Open label single arm phase I study of the pahramcokinetics and safety of Carfilzomib in subjects with advanced malignancies and varing degrees of hepatic impairment." Total funding will be $364,781. Fatima A. Rangwala of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "A randomized double blinded placebo controlled phase III study of adjuvant Regorafenib versus placebo for patient with stage IV coloractal cancer after curative treatment of liver metastases." Total funding will be $687,238. Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Gilead Sciences, Inc. for a project entitled "AZLI in lung transplant recipients." Total funding will be $46,188.[/tab] [/tabs]

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