New funding awards - December 2015

Sponsored Research

Pamela S. Douglas of Cardiology has received a sub-award (1R01-AI123001-01) through the Massachusetts General Hospital for a project entitled "Cardiovascular Disease Risk in HIV-infected Women: Sex-Specific Mechanisms of Risk and Risk Reduction among REPRIEVE Trial Participants." Total funding will be $1,833.

Paul B. Rosenberg of Cardiology has received an award from the National Ataxia Foundation for a project entitled "Contribution of store-operated calcium entry to calcium dysregulation in spinocerebellar ataxias." Total funding will be $30,000.

Ann J. Brown of Endocrinology, Metabolism, and Nutrition has received an award from the Doris Duke Charitable Foundation for a project entitled "Fund to Retain Clinical Scientists at Duke." Total funding will be $58,609.

Diego Bohorquez of Gastroenterology has received a sub-award (P30-DK034987-) through the Center for Gastrointestinal Biology and Disease for a project entitled "Pilot Grant for Gastrointestinal Biology Research." Total funding will be $30,000.

Leigh Boulware of General Internal Medicine has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Engaging patients, community, and health system stakeholders to establish PCOR priorities." Total funding will be $249,957.

Leigh Boulware of General Internal Medicine has received a sub-award (R01-DK102134-) through the University of Washington for a project entitled "CKD-Targeted Analyses of the Jackson Heart Study." Total funding will be $17,873.

Ara D. Metjian of Hematology has received a sub-award (U54-HL112303-) through the Washington University School of Medicine for a project entitled "ART Study (Rituximab as adjunct therapy with plasma exchange in TTP patients)." Total funding will be $2,500.

J. Brice Weinberg of Hematology has received an award (1R01-HL130763-01) from the National Institutes of Health for a project entitled "Nitric Oxide and Microvascular Dysfunction in Severe Malaria." Total funding will be $1,406,273.

Michael A. Hauser of Medical Genetics has received a sub-award (R01-EY022305-) through Harvard University for a project entitled "NEIGHBORHOOD Consortium for POAG Genomics." Total funding will be $31,800.

Brent A. Hanks of Medical Oncology has received a sub-award (U01-CA154967-) through the Fred Hutchinson Cancer Research Center for a project entitled "A Phase II, Open-label, Multicenter, Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with Malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant." Total funding will be $42,000.

Brent A. Hanks of Medical Oncology has received a sub-award (U01-CA154967-) through the Fred Hutchinson Cancer Research Center for a project entitled "Phase II Pilot Trial of an Indoleamine 2, 3,diosygenase -1 ( IDO1) Inhibitor (INCBO24360) Plus a Multipeptide Melanoma Vaccine ( MELTAC 12.1 ) in Patients with Advanced Melanoma." Total funding will be $28,000.

Hongyu Tian of Medical Oncology has received an award from the Susan G. Komen Breast Cancer Foundation for a project entitled "Fibulin-3 as a Novel Biomarker and Target in the Breast Tumor Microenvironment." Total funding will be $450,000.

Industry-sponsored Clinical Trials

Karen P. Alexander of Cardiology has received an award from Sanofi-Aventis U.S. for a project entitled "Independent Physician Study." Total funding will be $206,063.

Geoffrey S. Ginsburg of Cardiology has received an award from Singulex for a project entitled "CAD-associated biomarker evaluation." Total funding will be $278,250.

Igor Klem of Cardiology has received an award from Medtronic, Inc. for a project entitled "Multicenter Cardiac MRI Registry for SCD Risk Stratification in Non-Ischemic Cardiomyopathy." Total funding will be $95,000.

Renato D. Lopes of Cardiology has received an award from Amgen, Inc. for a project entitled "Amgen 785 Treatment in Postmenopausal Women." Total funding will be $847,767.

Martin A. Moseley III of Cardiology has received an award from BioResource International, Inc. for a project entitled "Proteomics Shared Resource-BioResource International SRA." Total funding will be $1,500.

L. Kristin Newby of Cardiology has received an award from Sentilus for a project entitled "POC 2-D Diffusion Assay for self-monitoring of BNP." Total funding will be $46,821.

Robert J. Noveck of Cardiology has received an award from MedImmune, Inc. for a project entitled "A Phase 1, Combined Single-and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MED14166 in Subjects with Type 2 Diabetes Mellitus." Total funding will be $109,495.

Jonathan P. Piccini of Cardiology has received an award from Spectranetics for a project entitled "Extraction Vs Capping Pacing and Defibrillator Leads." Total funding will be $149,881.

Eric Velazquez of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "LCZ696." Total funding will be $1,397,479.

Thomas J. Weber of Endocrinology, Metabolism, and Nutrition has received an award from Ultragenyx Pharmaceutical for a project entitled "An Open-Label, Single-Arm, Phase 3 Study to Evaluate the Effects of KRN23 on Osteomalacia in Adults with X-Linked Hypophosphatemia (XLH)." Total funding will be $41,518.

Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GT3 Study - HCV RNA Monitoring." Total funding will be $344,134.

Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GT12456 Study - HCV RNA Monitoring." Total funding will be $427,139.

Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "Gilead GS-US-334-0107 LOI." Total funding will be $25,000.

Jane E. Onken of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-326-1100 Dr. Onken Study." Total funding will be $163,168.

Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award from Adienne SA for a project entitled "Prospective, Phase I/II, randomized clinical study to compare BEGEDINA versus conventional treatment for treating steroid resistant acute GvHD." Total funding will be $92,706.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Astex Therapeutics Ltd. for a project entitled "A Phase 3, Multicenter, Open-label, Randomized Study of SGI-110 versus Treatment Choice (TC) in Adults with Previously Untreateed Acute Myeloid Leukemia (AML) Who Are Not Considered Candidates for Intensive Remission Induction Chemotherapy." Total funding will be $193,079.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from ADC Therapeutics Sarl for a project entitled "Phase I study of ADCT-301 in CD25+ AML." Total funding will be $186,416.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Astellas Pharma Global Development, Inc for a project entitled "Phase III study of ASP2215 vs Salvage Chemo in pts with R/R AML with FLT3 mutation." Total funding will be $198,538.

Thomas L. Ortel of Hematology has received an award from Daiichi Sankyo Inc for a project entitled "DU176b-A-U157/ A Phase 1, Open-Label, Single-Dose Non-Randomized Study To Evaluate Pharmacokinetics And Pharmacodynamics of Edoxaban In Pediatric Patients." Total funding will be $69,522.

Marilyn J. Telen of Hematology has received an award from Pfizer, Inc. for a project entitled "CSA - Pfizer 212511 B5201002 Phase 3 Randomized Multicenter Trial." Total funding will be $1,165,110.

Micah T. McClain of Infectious Diseases has received an award from GlaxoSmithKline for a project entitled "Analysis of bacterial viral signatures in GSK study cohort." Total funding will be $248,897.

Richard F. Riedel of Medical Oncology has received an award from Eli Lilly and Company for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin plus Olaratumab versus Doxorubicin plus Placebo in Patients with Advanced or Metastatic Soft Tissue Sarcoma." Total funding will be $616,897.

Richard F. Riedel of Medical Oncology has received an award from AADi LLC for a project entitled "A Phase 2 Multi-Center Investigation of Efficacy of ABI-009 (nab-rapamycin) in Patients with Advanced Malignant Perivascular Epithelioid Tumors (PEComa)." Total funding will be $148,031.

Gordana Vlahovic of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "AVeRT: Anti-PD-1 monoclonal antibody (nivolumab) in combination with DC Vaccines for the treatment of recurrent Grade III and Grade IV brain tumors."

Patricia Lugar of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Dyax Corporation for a project entitled "The HELP Study." Total funding will be $263,726.

Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from AstraZeneca AB for a project entitled "A multicentre, randomized, parallel group, Phase 3 safety extension study to evaluate the safety and tolerability of benralizumab (MEDI-563) in asthmatic adults and adolescents on inhaled corticosteroid plus long-acting Я2 agonist (BORA)." Total funding will be $166,860.

Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from VentureWell for a project entitled "Physao E-Team Proposal, Stage 1." Total funding will be $5,000.

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