New funding awards - December 2017

Sponsored Research

Michael D. Gunn of Cardiology has received an award from the Burroughs Wellcome Fund for a project entitled "Physician-Scientist Institutional Award: Increasing Opportunities for the M.D. Interested in a Research Career." Total funding will be $30,000.

Tracy Y. Wang of Cardiology has received an award from the AstraZeneca Healthcare Foundation for a project entitled "AZ_CLiPPeR: Association of Net Worth with Cardiovascular Outcomes and Medication Adherence in Patients with Acute Myocardial Infarction." Total funding will be $40,000.

Matthew D. Hirschey of Endocrinology, Metabolism, and Nutrition has received an award (1R56-AG052568-01) from the National Institutes of Health for a project entitled "Novel SIRT4 Enzymatic Activity Influence Cellular Mechanisms of Aging." Total funding will be $397,500.

Deborah Muoio of Endocrinology, Metabolism, and Nutrition has received a sub-award (7R01-HL128349-03) through the University of Pennsylvania for a project entitled "Probing the Role of Mitochondrial Short-Chain Carbon Homeostasis in the Hypertrophied and Failing Heart." Total funding will be $251,112.

Richard T. Premont of Gastroenterology has received a sub-award (1R01-DK113159-01A1) through the Medical University of South Carolina for a project entitled "A Molecular Approach to the Pathogenesis of Portal Hypertension." Total funding will be $10,009.

Cathleen S. Colon-Emeric and Heather Whitson of Geriatrics have received an award (1UH2-AG056925-01) from the National Institutes of Health for a project entitled "Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative)." Total funding will be $2,022,779.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received a sub-award (1T32-CA211056-01A1) through the University of North Carolina - Chapel Hill for a project entitled "UNC - Duke Immunotherapy Training Program." Total funding will be $135,690.

Lindsay A. Rein of Hematological Malignancies and Cellular Therapy has received an award from the American Society of Hematology for a project entitled "Targeting Beta-arrestins in myeloid malignancies." Total funding will be $50,000.

Mehri McKellar of Infectious Diseases has received a sub-award (NCH17-F999) through the NC Dept of Health and Human Services for a project entitled "Housing Opportunities for Persons with AIDS- Region Six." Total funding will be $94,878.

Mehri McKellar of Infectious Diseases has received a sub-award (NCH17-F999) through the NC Department of Health and Human Services for a project entitled "Housing Opportunities for Persons with AIDS- Region Seven." Total funding will be $188,581.

Rebekah W. Moehring of Infectious Diseases has received an award (200-2018-96423) from the Centers for Disease Control and Prevention for a project entitled "Predictors of Antimicrobial Exposure for application in the Standardized Antimicrobial Administration Ratio Risk Adjustment Strategy." Total funding will be $356,850.

Myaing M. Nyunt of Infectious Diseases has received an award from the Bill and Melinda Gates Foundation for a project entitled "Operations." Total funding will be $4,410,555.

Myaing M. Nyunt of Infectious Diseases has received an award from the Bill and Melinda Gates Foundation for a project entitled "Objective 3." Total funding will be $280,764.

Myaing M. Nyunt of Infectious Diseases has received an award from the Bill and Melinda Gates Foundation for a project entitled "Objective 2." Total funding will be $1,960,762.

Myaing M. Nyunt of Infectious Diseases has received an award from the Bill and Melinda Gates Foundation for a project entitled "Objective 1.1." Total funding will be $1,259,464.

Ephraim L. Tsalik of Infectious Diseases has received an award (1 PC1 AI 134343-01) from the National Institutes of Health for a project entitled "AMR Challenge Award." Total funding will be $50,000.

Syed Y. Zafar of Medical Oncology has received an award from the American Cancer Society Cancer Action Network for a project entitled "Using AACT - to answer Oncology landscape portfolio of open trials." Total funding will be $12,202.

Christopher Cox of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (5U01-HL123009-04) through the Vanderbilt University for a project entitled "Reevaluation of Systemic Early neuromuscular blockade."

Robert M. Tighe of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R01-ES027574-01A1) from the National Institutes of Health for a project entitled "CXCL10/CXCR3 regulation of ozone-induced epithelial permeability." Total funding will be $3,073,325.

Industry-sponsored Clinical Trials

John K. Harrison of Cardiology has received an award from Medtronic, Inc. for a project entitled "Transcatheter Mitral Valve Replacement with the Medtronic Intrepidї TMVR System in patients with severe sympotmatic mitral regurgitation." Total funding will be $309,959.

William S. Jones of Cardiology has received an award from Cardiovascular Systems Inc. for a project entitled "CSI Educational Program Agreement VIII." Total funding will be $17,700.

Robert J. Mentz of Cardiology has received an award from Akros Medical for a project entitled "JTT-251_HF Trial." Total funding will be $4,054,891.

Manal F. Abdelmalek of Gastroenterology has received an award from Cirius Therapeutics for a project entitled "Cirius EMMINENCE." Total funding will be $154,778.

Andrew J. Muir of Gastroenterology has received an award from Proteus Digital Health, Inc. for a project entitled "The purpose of this study is to evaluate the use of passive, wirelessly observed therapy (WOT) using Proteus Discoverї for maintaining HCV treatment adherence and achieving viral titer suppression in HCV-infected patients." Total funding will be $57,954.

James Davis of General Internal Medicine has received an award from Axsome Therapeutics Inc. for a project entitled "A Randomized, Double-Blind Study to Evaluate the Impact of AXS-05 on Smoking Behavior." Total funding will be $386,660.

Matthew S. McKinney of Hematological Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "A Phase 2, Open-Label, 2-C Cohort Study of INCB050465, A P13K @ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma With or Without Prior Exposure to a BTK Inhibitor (CITADEL-204)." Total funding will be $255,656.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from MEI Pharma, Inc. for a project entitled "A Two-Stage, Open-Label Followed by Placebo-Controlled Phase 2 Study of Pracinostat and Azacitidine in Patients with IPSS-R High and Very High Risk Myelodysplastic Syndromes Previously Untreated with Hypomethylating Agents." Total funding will be $77,499.

Nirmish R. Shah of Hematology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Adherence to iron chelation therapy pediatric patients with SCD - retrospective study." Total funding will be $3,000.

April K. Salama of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A Phase 3, Randomized Study of Adjuvant Immunotherapy with Nivolumab Combined with Ipilimumab versus Nivolumab Monotherapy after Complete Resection of Stage IIIb/c/d or Stage IV Melanoma." Total funding will be $360,784.

April K. Salama of Medical Oncology has received an award from Immunocore Limited for a project entitled "A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared with Investigator's Choice in HLA-A*0201 Positive Patients with Previously Untreated Advanced Uveal Melanoma." Total funding will be $578,917.

Coral X. Giovacchini (Mentor: Kamran Mahmood) of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Boston Scientific Corporation for a project entitled "IP Fellowship." Total funding will be $30,010.

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