New funding awards - February 2020

Sponsored Research

Michael Gunn of Cardiology has received an award (1R21-AI144749-01A1) from the National Institutes of Health for a project entitled "Generation of antibodies specific for optimal non-HRP2 malaria diagnostic antigens." Total funding will be $434,948.

Adrian Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet Phase II TO#17- DCRI Leadership." Total funding will be $1,703,678.

Manesh Patel of Cardiology has received an award from the VIVA Physicians Inc. for a project entitled "BEST-VIVA Registry (vCLI)." Total funding will be $500,000.

Nelson E. Airewele (Mentor: Lindsay King) of Gastroenterology has received an award from the St Marys Hospital for a project entitled "Advanced/Transplant Hepatology Fellowship." Total funding will be $120,263.

Patrick Sullivan of Geriatrics has received a sub-award (1R-56NS112166-01) through the Roskamp Institute for a project entitled "Influence of APOE Genotype on the neurodegenerative sequelae of repetitive mild TBI in an hTau mouse model." Total funding will be $93,003.

Gregory Taylor of Geriatrics has received an award (1R01-AI148243-01) from the National Institutes of Health for a project entitled "IRGM proteins as regulators of inflammation." Total funding will be $2,374,830.

Oluwatoyosi Onwuemene of Hematology has received an award from the Robert Wood Johnson Foundation for a project entitled "Developing apheresis-specific outcomes to facilitate a multi-center study of therapeutic plasma exchange in heparin-induced thrombocytopenia." Total funding will be $420,000.

Brice Weinberg of Hematology has received an award (5R01-HL130763-04S1) from the National Institutes of Health for a project entitled "Nitric Oxide and Microvascular Dysfunction in Severe Malaria." Total funding will be $59,999.

Jason Stout of Infectious Diseases has received a sub-award () through the NC DHHS for a project entitled "Epidemiology/General Communicable Disease Control." Total funding will be $88,722.

Nathan Thielman of Infectious Diseases has received a sub-award (D43-TW009337-) through the Vanderbilt University Medical Center for a project entitled "Prevalence of hypertension among postpartum women with pre-eclampsia in Kenya." Total funding will be $84,381.

Nathan Thielman of Infectious Diseases has received a sub-award (D43TW009337) through the Vanderbilt University Medical Center for a project entitled "Evaluation of Chronic Hypoxemia from Cardiopulmonary Disease Among Patients in Western Kenya and Perspectives on Oxygen Therapy." Total funding will be $25,920.

Scott Antonia of Medical Oncology has received a sub-award () through the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Tumor Infiltrating lymphocyte adoptive T cell therapy for NSCLC." Total funding will be $221,094.

William St Clair of Rheumatology has received a sub-award (5UM1-AI109565-06) through the Benaroya Research Institute at Virginia Mason for a project entitled "Subaward Agreement - Benaroya to Duke - Immune Tolerance Network FY19ITN355 - Protocol Chair - Year 1." Total funding will be $12,745.

Industry-sponsored Clinical Trials

Islam Othman of Cardiology has received an award from Boston Scientific Corporation for a project entitled "A U.S. Post-Approval Study of the SYNERGY 4.50/5.0 mm Everolimus-Eluting Platinum Chromium Coronary Stent System  EVOLVE 4.5/5.0." Total funding will be $43,674.

Mark Herman of Endocrinology has received an award from Eli Lilly and Company for a project entitled "The Role of KHK and ChREBP in Fructose-Induced Cardiorenal Disease." Total funding will be $125,000.

Hans-Ewald Hohmeier of Endocrinology has received an award from Eli Lilly and Company for a project entitled "Pilot Study: Testing of Comprehensive Mitochondrial Profiling Platform in Islet cells." Total funding will be $50,000.

Ranee Chatterjee Montgomery of General Internal Medicine has received an award from Bristol-Myers Squibb Company for a project entitled "GUARD-AF." Total funding will be $2,709,197.

Danielle Brander of Hematologic Malignancies and Cellular Therapy has received an award from Verastem Oncology for a project entitled "A Multi-Center, Phase 2, Open-label Parallel Cohort Study of Efficacy and Safety of Duvelisib in Patients with Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)." Total funding will be $212,180.

Taewoong Choi of Hematologic Malignancies and Cellular Therapy has received an award from Nektar Therapeutics for a project entitled "A Phase I, Open-Label, Multi-Center, Dose Escalation and Dose Expansion Study of NKTR-255 as a single agent in relapsed or refractory hematological malignancies and in combgination with Daratumumab as a Salvage Regimen for Multiple Myeloma." Total funding will be $324,795.

Carlos Decastro of Hematologic Malignancies and Cellular Therapy has received an award from Apellis Pharmaceuticals, Inc for a project entitled "Apellis AP2-307--Extension PNH." Total funding will be $125,551.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Forty Seven, Inc. for a project entitled "Ph1b in patients with Hem Malignancies." Total funding will be $598,473.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A phase Ib, multi-arm, open-label, study of HDM201 in combination with MBG453 or venetoclax in adult subjects with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS)." Total funding will be $231,378.

Ahmed Galal of Hematologic Malignancies and Cellular Therapy has received a sub-award (14926) through Sarah Cannon Research Institute for a project entitled "A Phase I Study of Microtransplantation in Combination with Nivolumab for Relapsed or Refractory B Cell Non-Hodgkin Lymphomas." Total funding will be $50,000.

Sarah Sammons of Medical Oncology has received an award from Eli Lilly and Company for a project entitled "Evaluation of the effects of endocrine therapy and abemaciclib on host and tumor immune cell repertoire/function in advanced ER+/HER2- breast cancer." Total funding will be $1,248,124.

John Strickler of Medical Oncology has received an award from Amgen, Inc. for a project entitled "A Phase 1b, Master Protocol Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 510 in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation." Total funding will be $392,789.

Momen Wahidi of Pulmonary has received an award from Spiration, Inc. for a project entitled "Spiration Valve System (SVS) Post Market Registry Study for Severe Emphysema P180007/PAS002." Total funding will be $158,521.

Megan Clowse of Rheumatology has received an award from UCB Pharma, Inc. for a project entitled "STUDY "A MULTICENTER, LONGITUDINAL, PROSPECTIVE, PHARMACOKINETIC, PHASE 1B STUDY IN WOMEN WITH CHRONIC INFLAMMATORY DISEASES TREATED WITH CIMZIA® (CERTOLIZUMAB PEGOL) DURING PREGNANCY"." Total funding will be $82,998.

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