New funding awards - January 2012

By ajz6@dhe.duke.edu
Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards. [tabs style="vertical"] [tab title="Sponsored research"]Allison Ashley-Koch of Medical Genetics has received a sub-award (2P42-ES005948-18A1) through the University of North Carolina - Chapel Hill for a project entitled "Elucidating Outcome and Risk from Improved Exposure Assessment and Mechanistic Studies." Total funding will be $70,820. Gerard Blobe of Medical Oncology has received a sub-award (1R33-CA155618-01A1) through the University of North Carolina - Chapel Hill for a project entitled "Array Microscope Assay for Cancer Cell Mechanics." Total funding will be $40,785. Gary Felker of Cardiology has received an award (1U10-HL110312-01) from the National Institutes of Health for a project entitled "Heart Failure Clinical Research Network Regional Clinical Center (U10)." Total funding will be $506,123. Gary Felker of Cardiology has received an award (1U10-HL110312-01) from the National Institutes of Health for a project entitled "Heart Failure Network - RCC." Total funding will be $360,706. Larry Goldstein of Neurology has received a sub-award (3R01-NS043322-04S1) through the Yale University for a project entitled "THE STROKE HOSPITALIZATION IN THE ELDERLY WITH MEDICARE FEE-FOR-SERVICE." Total funding will be $142,816. Virginia Kraus of Rheumatology has received an award from the Arthritis Foundation for a project entitled "Post-translationally Modified Proteins as Biomarkers of OA." Total funding will be $100,000. William Kraus of Cardiology has received an award (1F32-HL112575-01) from the National Institutes of Health for a project entitled "Attenuated Functional Capacity in Combined Heart Failure & Type 2 Diabetes: ...." Total funding will be $47,636. P. Kelly Marcom of Medical Oncology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Novartis Breast Cancer Practicum - Breast Oncology Training Practicum." Total funding will be $59,740. Christopher O'Connor of Cardiology has received an award (1U10-HL110312-01) from the National Institutes of Health for a project entitled "Heart Failure Network: Clinical Research Services Development Core." Total funding will be $145,417. Scott Palmer of Pulmonary, Allergy & Critical Care Medicine has received an award (1U01-HL110967-01) from the National Institutes of Health for a project entitled "Lung Repair and Regeneration Consortium Administrative Coordinating Center." Total funding will be $935,250. Adam Perlman of General Medicine has received an award (7R01-AT004623-04) from the National Institutes of Health for a project entitled "Multisite RCT Investigating the Efficacy of Massage in Osteoarthritis." Total funding will be $697,136. Wiley Schell of Infectious Disease has received a sub-award (2R44-HG005186-02) through the Advanced Liquid Logic for a project entitled "Miniaturized DNA Sequencer for Identification of Microbial Pathogens." Total funding will be $54,859. John Sundy of Pulmonary, Allergy & Critical Care Medicine has received an award from the Peking University for a project entitled "Student education / fellowship program." Total funding will be $10,000. Qun Zhao of Neurology has received a sub-award (5R01-AG037619-02) through the Cognosci, Inc. for a project entitled "Small Molecule Screen for Apolipoprotein-E/Alzheimer's Disease." Total funding will be $118,358.[/tab] [tab title="Industry-sponsored clinical trials"]Kimberly L. Blackwell of Medical Oncology has received an award from the Genentech, Inc. for a project entitled " A Randomized, Phase II, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating The Safety and Efficacy of METMAB and/or Bevacizumab In Combination With Paclitaxel In Patients With metastatic, Triple-Negative Breast Cancer." Total funding will be $274,904. James Burke of Neurology has received an award from the Merck Sharp & Dohme for a project entitled "Investigation of Biomarkers of Disease State in Alzheimer's Disease and non-AD dementias." Total funding will be $294,799. Cristina Gasparetto of Cell Therapy has received an award from the Core Science Solutions for a project entitled "A Multi Center Phase I, Open Label, Dose Finding Pilot Study of the Combination of Carfilzomib and Pomalidomide with Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma." Total funding will be $117,361. Daniel George of Medical Oncology has received an award from the Genentech, Inc. for a project entitled "A Phase II, Open Label, Randomized Study of GDC-0980 Versus Everolimus in Patients with Metastatic Renal Cell Carcinoma Who Have Progressed On Or Following VEGF-Targeted Therapy." Total funding will be $188,716. Michael Harrison of Medical Oncology has received an award from the Bristol-Myers Squibb for a project entitled "An Exploratory Study to Investigate the Immunomodulatory Activity of Various Dose Levels of Anti Programmed-Death-1 (PD-1) Antibody (BMS-936558) in Subjects with Metastatic Clear Cell Renal Cell Carcinoma (RCC).." Total funding will be $260,833. Bradley Kolls of Neurology has received an award from the BrainScope Company, Inc. for a project entitled "Assessment of head Injury in the Emergency Department: Clinical Validation of the Brainscope Ahead Technology (B-AHEAD II Trial)." Total funding will be $44,044. John Middleton of Nephrology has received an award from the Otsuka Pharmaceutical Co., Ltd. for a project entitled "Overture PKD 291 (AKPKD)." Total funding will be $39,250. Lake Morrison of Pulmonary, Allergy & Critical Care Medicine has received an award from the Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Effect of Oral BIBF 1120 on Forced Vital Capacity decline in IPF." Total funding will be $53,450. Andrew Muir of Gastroenterology has received an award from the Vertex Pharmaceuticals Inc. for a project entitled "Phase 4 Study of Telaprevir, Peginterferon Alfa-2a,Ribavirin in Treatment-Experienced African American w/ Genotype1 Chronic Hepatitis C vs Historical Data of Non African American with no Sustained Viral Response With Prior Course Interferon Based Therapy." Total funding will be $29,949. Andrew Muir of Gastroenterology has received an award from the Intercept Pharmaceuticals, Inc for a project entitled "Clinical Trial Protocol 747-301 Obeticholic Acid (OCA)." Total funding will be $53,738. Andrew Muir of Gastroenterology has received an award from the Pharmasset Inc for a project entitled "The QUANTUM Study: An Study to Investigate Safety, Tolerability, PK and PD following Administration of Regimens Containing PSI-352938, PSI-7977, and RBV in Patients with Chronic HCV Infection Protocol #: P2938-0721." Total funding will be $26,656. Susanna Naggie of Infectious Disease has received an award from the Vertex Pharmaceuticals Inc. for a project entitled "Phase 3 Telaprvir with Peginterferon and Ribavirin on coinfected Hep C and HIV." Total funding will be $40,000. Jane Onken of Gastroenterology has received an award from the Centocor for a project entitled "A Phase 3, Randomized, Double-blind, Placebo controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Ustekinumab Maintenance Therapy in Subjects with Moderately to Severely Active Crohns Disease (IMUNITI) -CNTO1275CRD3003." Total funding will be $24,210. Jane Onken of Gastroenterology has received an award from the Centocor for a project entitled "A Phase 3, Randomized, Double-blind, ... Study to Evaluate the Safety & Efficacy of Ustekinumab Induction Therapy in Subjects with Crohns Disease Who Have Failed or Are Intolerant to TNF Antagonist Therapy (UNITI-1)." Total funding will be $23,980. April Salama of Medical Oncology has received an award from the Morphotek, Inc for a project entitled "A Study of the Efficacy and PK/PD Relationship of Monotherapy MORAb-004 in Subjects with Metastatic Melanoma." Total funding will be $341,477. John Strickler of Medical Oncology has received an award from the Abbott Laboratories for a project entitled "A Multicenter, phase I/Ib, Open-label, Dose-Escalation Study of ABT-700, a monoclonal antibody, in subjects with advanced solid tumors." Total funding will be $200,922. John Strickler of Medical Oncology has received an award from the Eisai, Inc. for a project entitled "An open-label, multicenter, randomized Phase IB/II study of E7050 in combination with Cisplatin and Capcitabine alone in patients with advanced or metastatic solid tumors and previously untreated gastric cancer." Total funding will be $329,840. Cameron Wolfe of Infectious Disease has received an award from the Genentech, Inc. for a project entitled "Roche Tamiflu Protocol NV20234, A double-blind, randomized, stratified, multi-center trial evaluating conventional and high dose oseltamivir in the treatment of immunocompromised patients with influenza." Total funding will be $61,774.[/tab] [/tabs]

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