New funding awards - January 2019

Sponsored Research

Christopher Kontos of Cardiology has received an award from the American Heart Association for a project entitled "A Novel Molecular Regulator of Vascular Homeostasis." Total funding will be $77,000.

Daniel Mark of Cardiology has received an award (2T32-HL069749-16) from the National Institutes of Health for a project entitled "Postdoctoral Training in Cardiovascular Clinical Research." Total funding will be $2,610,280.

Kishan Parikh of Cardiology has received an award (2037894) from the National Institutes of Health for a project entitled "Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction." Total funding will be $0.

Kathleen Cooney of Chair's Office has received a sub-award (W81XWH-17-1-0114) through the Wayne State University for a project entitled "The Contribution of Rare Variants in Familial Clustering of Prostate and Breast Cancer in African Americans." Total funding will be $32,973.

Jatin Roper of Gastroenterology has received an award from the American Gastroenterological Association for a project entitled "Mechanisms of niche cell function in colorectal cancer." Total funding will be $30,000.

Rowena Dolor of General Internal Medicine has received a sub-award () through the Weill Medical College of Cornell University for a project entitled "The CAPTURE Study: Validatiing a unique COPD screening tool in primary care." Total funding will be $1.

Nia Mitchell of General Internal Medicine has received an award (1R01-AG058725-01A1) from the National Institutes of Health for a project entitled "Changes in Weight and Physical Function for Older African American Women in National, Peer-Led, Community-Based Weight Loss Program." Total funding will be $2,589,644.

Heather Whitson of Geriatrics has received a sub-award (5 R24 AG045050-04) through the University of Massachusetts Medical School for a project entitled "Advancing Geriatrics Infrastructure and Network Growth (AGING) Initiative." Total funding will be $29,877.

Oluwatoyosi Onwuemene of Hematology has received an award from the American Society for Apheresis for a project entitled "American Society for Apheresis (ASFA) Heparin Induced Thrombocytopenia Registry." Total funding will be $8,000.

Thomas Ortel of Hematology has received a sub-award (6NU38-OT18-000280-01-01) through the Association of University Centers on Disabilities for a project entitled "Evaluation, analysis, and dissemination of population-based cancer-associated venous thromboembolism (VTE) data." Total funding will be $175,000.

Thomas Ortel of Hematology has received a sub-award (1R01-HL142647-01) through the Case Western Reserve University for a project entitled "APLA Grant." Total funding will be $29,259.

Hannah E. Brown (Mentor: Andrew Alspaugh) of Infectious Diseases has received an award (F31-AI140427-01A1) from the National Institutes of Health for a project entitled "Defining pH-Sensing in Fungal Virulence." Total funding will be $117,561.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "One Health Training Program Duke University 2018-2019: Pakistan." Total funding will be $351,307.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "One Health Training Program Duke University 2018-2019: MENA." Total funding will be $345,000.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal interface in Morocco." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal interface in Lebanon." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal interface in Yemen." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal interface in Turkey." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Environmental Surveillance of Pathogens at the Human-Animal Interface in Morocco." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Environmental Surveillance of Pathogens at the Human-Animal Interface in Lebanon." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Environmental Surveillance of Pathogens at the Human-Animal Interface in Yemen." Total funding will be $0.

Gregory Gray of Infectious Diseases has received an award (SISNCT19CA0002) from the US Department of State for a project entitled "Environmental Surveillance of Pathogens at the Human-Animal Interface in Turkey." Total funding will be $0.

John Perfect of Infectious Diseases has received an award from the University of Alabama at Birmingham for a project entitled "MSG-15." Total funding will be $41,720.

Steven Patierno of Medical Oncology has received an award from the Prostate Cancer Foundation for a project entitled "Targeting RNA splicing in race-related aggressive and lethal prostate cancer." Total funding will be $1,000,000.

Xiaohan Lu (Mentor: Steven Crowley) of Nephrology has received an award from the American Heart Association for a project entitled "Dendritic cells activate pro-hypertensive T cells to drive sodium reaborption in kidney." Total funding will be $51,844.

Jens Titze of Nephrology has received a sub-award (5R01-HL133860-03) through the Vanderbilt University Medical Center for a project entitled "Tissue, Sodium, Inflammation, and Blood Pressure in MESA." Total funding will be $30,118.

Jens Titze of Nephrology has received a sub-award (R01-HL140145-01) through the Vanderbilt University Medical Center for a project entitled "Salt, Blood Pressure, and Inflammation." Total funding will be $13,616.

Christina Wyatt of Nephrology has received a sub-award (R01-HD089843-02) through the University of Washington for a project entitled "Impact of Concurrent Initiation of DMPA and Tenofovir PrEP on Bone Loss in Young Women." Total funding will be $12,699.

Christina Wyatt of Nephrology has received a sub-award (R01-DK108438-04) through the University of Alabama at Birmingham for a project entitled "Effect of Pitavastatin on Kidney Function in HIV-infected Persons." Total funding will be $10,160.

Christina Wyatt of Nephrology has received a sub-award (R01-DK117675-01) through the University of Alabama at Birmingham for a project entitled "Genetic, environmental, and histologic basis for kidney disease among persons living with HIV." Total funding will be $6,788.

Scott Palmer of Pulmonary has received an award from the Cystic Fibrosis Foundation for a project entitled "Genetics of Acute Rejection and Chronic Lung Allograft Dysfunction." Total funding will be $355,316.

Scott Palmer of Pulmonary has received a sub-award (5U01-AI063594-15) through the Mount Sinai School of Medicine for a project entitled "Do changes in bronchoalveolar fluid cells correlate with immune polarization, acute rejection, lung injury, or chronic lung allograft dysfunction (CLAD) after lung transplantation? CTOT." Total funding will be $19,912.

Robert Tighe of Pulmonary has received a sub-award (1R01-ES028829-01A1) through the East Carolina University for a project entitled "Novel role for CD163 in ozone induced alterations of pulmonary immunity." Total funding will be $156,488.

Megan Clowse of Rheumatology has received a sub-award (PPRND-1507-32163) through the University of Alabama at Birmingham for a project entitled "Harnessing PCORnet to Study Comparative Effectiveness and Safety of Biologic Treatments." Total funding will be $34,511.

Virginia Kraus of Rheumatology has received an award from the Foundation for the National Institutes of Health for a project entitled "Osteoarthritis Biomarkers Qualification Project (OABQP)." Total funding will be $34,973.

Rebecca Sadun of Rheumatology has received a sub-award (OISE-9531011) through the CRDF Global for a project entitled "High-throughput analysis of human memory B cells and antibodies against flavivirus E protein in Asia-Pacific regions.." Total funding will be $12,500.

Industry-sponsored Clinical Trials

William Herzog of Cardiology has received an award from Amgen, Inc. for a project entitled "Galactic-HF." Total funding will be $331,406.

Martin Moseley III of Cardiology has received an award from UCB Biopharm SPRL for a project entitled "UCB Biopharm SPRL." Total funding will be $10,400.

Ann Navar of Cardiology has received an award from Amgen, Inc. for a project entitled "EHR Great Registry." Total funding will be $178,007.

Jonathan Piccini of Cardiology has received an award from American Heart Association for a project entitled "Get With The Guidelines AHA Measure Reliability Testing SOW #18." Total funding will be $16,511.

Andrew Wang of Cardiology has received an award from MyoKardia, Inc. for a project entitled "MAVA-EXTENSION (MYK-461-007)." Total funding will be $348,189.

Jonathan Campbell of Endocrinology has received an award from Eli Lilly and Company for a project entitled "Eli Lilly SRA." Total funding will be $318,758.

Mark Feinglos of Endocrinology has received an award from Merck for a project entitled "MK-0431-082-0006 Reopen." Total funding will be $6,750.

Karen Chachu of Gastroenterology has received an award from Janssen Research & Development, LLC for a project entitled "Protocol CNTO1275CRD3007." Total funding will be $145,246.

Carlos Decastro of Hematologic Malignancies and Cellular Therapy has received an award from Apellis Pharmaceuticals, Inc for a project entitled "A Phase III, Randomized, Multi-Center, Open-Label, Active-Comparator Controlled Study To Evaluate the Efficacy and Safety of APL-2 in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)." Total funding will be $283,810.

Matthew McKinney of Hematologic Malignancies and Cellular Therapy has received an award from Molecular Templates, Inc. for a project entitled "A Phase 2a Open-label Study to Investigate Safety and Tolerability (including the MTD), Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of MT-3724 in Combination with Gemcitabine and Oxaliplatin in Subjects with Relapsed or Refractor." Total funding will be $273,837.

Ara Metjian of Hematology has received an award from Genentech, Inc. for a project entitled "Phase IV open label study of Emicizumab Prophylaxis in Hemophila A patients undergoing minor surgery." Total funding will be $56,054.

Jeffrey Clarke of Medical Oncology has received an award from Adaptimmune Limited for a project entitled "Adaptimmune MAGE A-4." Total funding will be $843,723.

Brent Hanks of Medical Oncology has received an award from Sanofi US for a project entitled "A Phase 1/1b first-in-human dose escalation and expansion study for theevaluation of safety, pharmacokinetics, pharmacodynamics and anti-tumor activity of SAR439459 administered intravenously as monotherapy and in combination with REGN2810 in adult." Total funding will be $576,351.

Michael Harrison of Medical Oncology has received an award from Clovis Oncology, Inc. for a project entitled "ATLAS: A Phase 2, Open-label Study of Rucaparib in Patients with Locally Advanced or Metastatic Urothelial Carcinoma." Total funding will be $138,325.

Sundhar Ramalingam of Medical Oncology has received an award from Exelixis, Inc for a project entitled "Development of a cabozantinib (Cabometyx)symptom management application for use in patients with renal cancer"; XL184-IST50." Total funding will be $147,427.

John Strickler of Medical Oncology has received an award from Amgen, Inc. for a project entitled "A Phase 1, First-in-Human, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 510 in Subjects With Advanced Solid Tumors With a Specific KRAS Mutation." Total funding will be $645,797.

Kamran Mahmood of Pulmonary has received an award from Boston Scientific Corporation for a project entitled "IP Fellowship for Luke Seaburg." Total funding will be $30,067.

Ankoor Shah of Rheumatology has received a sub-award (1R43-AI138631-01) through Affinergy, LLC for a project entitled "Affinergy Scleroderma Antibody study." Total funding will be $5,465.

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