Sponsored research
Dennis M. Abraham of Cardiology has received an award (1K08-HL125905-01) from the National Institutes of Health for a project entitled "TREK-1 in fibroblast differentiation and cardiac fibrosis development." Total funding will be $638,335.
William E. Kraus of Cardiology has received an award (EP-15-W-000055) from the Environmental Protection Agency for a project entitled "CATHGEN Clinical Data Project." Total funding will be $50,000.
William E. Kraus of Cardiology has received an award (1U24-AG047121-01A1) from the National Institutes of Health for a project entitled "Biomarkers of Caloric Restriction in Humans: the CALERIE Biorepository." Total funding will be $2,781,046.
Robert J. Lefkowitz of Cardiology has received an award (2R01-HL016037-43) from the National Institutes of Health for a project entitled "Molecular Regulation of Cardiovascular 7 TM Receptors." Total funding will be $1,791,407.
Lan Mao of Cardiology has received an award (2P01-HL075443-11) from the National Institutes of Health for a project entitled "Core B - Comprehensive Mouse Physiology & Phenotyping", a part of Howard A. Rockman's project entitled "Novel Mechanisms and Therapies in Heart Failure."
Manesh R. Patel of Cardiology has received a sub-award (ME-1402-10638) through Emory University for a project entitled "Patient-Centered Approaches to Research Enrollment Decisions in Acute Cardiovascular Disease." Total funding will be $3,000.
Eric D. Peterson of Cardiology has received an award from the Food and Drug Administration for a project entitled "IPA with the FDA for Jonathan D. McCall." Total funding will be $73,326.
Eric D. Peterson of Cardiology has received an award from the Food and Drug Administration for a project entitled "IPA with the FDA for Jean Bolte." Total funding will be $503,531.
Howard A. Rockman of Cardiology has received an award (2R01-HL056687-18) from the National Institutes of Health for a project entitled "Mechanisms of Maladaptation in Heart Failure." Total funding will be $1,590,000.
Howard A. Rockman of Cardiology has received an award (2P01-HL075443-11) from the National Institutes of Health for a project entitled "Core A - Administrative Core."
Howard A. Rockman of Cardiology has received an award (2P01-HL075443-11) from the National Institutes of Health for a project entitled "Beta Arrestin Biased Mechanosensitive Angiotensin Receptor Signaling."
Jialu Wang (Mentor: Howard A. Rockman) of Cardiology has received an award from the American Heart Association for a project entitled "Carvedilol Stimulated Gi-beta-Arrestin Biased Beta1-Adrenergic Receptor Signaling." Total funding will be $50,000.
Kunhong Xiao of Cardiology has received an award (2P01-HL075443-11) from the National Institutes of Health for a project entitled "Core C - Proteomics Core", a part of Howard A. Rockman's project entitled "Novel Mechanisms and Therapies in Heart Failure."
Jenny Tong of Endocrinology, Metabolism, and Nutrition has received an award (7R01-DK097550-03) from the National Institutes of Health for a project entitled "The Role of Ghrelin to Regulate Insulin Secretion in Health and Diabetes." Total funding will be $515,163.
Cynthia A. Moylan of Gastroenterology has received an award from the American College of Gastroenterology for a project entitled "Epigenetics and the Development of Nonalcoholic Fatty Liver Disease." Total funding will be $300,000.
Corrine I. Voils of General Internal Medicine has received an award (1R34-HL125669-01A1) from the National Institutes of Health for a project entitled "Incentivizing Behavior Change Skills to Promote Weight Loss." Total funding will be $715,500.
Harvey Jay Cohen of Geriatrics has received an award from the John A. Hartford Foundation, Inc. for a project entitled "John A. Hartford Foundation's Centers of Excellence (CoE)." Total funding will be $81,000.
Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award through the University of Texas Health Science Center at Houston for a project entitled "Phase III RECRUIT Study CTN 1505." Total funding will be $5,000.
Marilyn J. Telen of Hematology has received an award from the Doris Duke Charitable Foundation for a project entitled "High-throughput Metabolite Profiling and Genetic Analyses to Identify Novel Predictive Biomarkers of SCD-related Complications." Total funding will be $456,000.
Marilyn J. Telen of Hematology has received an award (1R21-DK106509-01) from the National Institutes of Health for a project entitled "Factor XIII and Fibrinogen: Mechanisms of Genetic Risk in SCD-Related Priapism." Total funding will be $445,000.
Mehri McKellar of Infectious Diseases has received an award from the NC DHHS for a project entitled "Substance Abuse Center-5 (SAC-5): Counseling, Testing and Referral in Durham, Caswell, Orange, Person and Wake." Total funding will be $75,000.
Mehri McKellar of Infectious Diseases has received an award from the NC DHHS for a project entitled "Housing Opportunities for Persons with AIDS- Region Six." Total funding will be $206,180.
John Perfect of Infectious Diseases has received an award (1P01-AI104533-01A1) from the National Institutes of Health for a project entitled "Administrative Core C." Total funding will be $475,208.
Nathan M. Thielman of Infectious Diseases has received an award (T32-AI007392-26) from the National Institutes of Health for a project entitled "Interdisciplinary Research Training Program in AIDS." Total funding will be $2,113,320.
Chris Woods of Infectious Diseases has received an award through the National University of Singapore for a project entitled "An Innovative Model for Detecting Interspecies Disease Transmission and Novel Pathogen Detection at Lola Ya Bonobo Sanctuary, Democratic Republic of Congo." Total funding will be $100,000.
Gerard C. Blobe of Medical Oncology has received an award (1R21-CA198365-01) from the National Institutes of Health for a project entitled "Dissecting ALK4 Function in Cancer Progression." Total funding will be $207,495.
Kathryn Ware (Mentor: Andrew Armstrong) of Medical Oncology has received an award (1F32-CA192630-01A1) from the National Institutes of Health for a project entitled "AR variant regulation during EMT and disease progression." Total funding will be $168,198.
Lesley H. Curtis of Other Medicine has received a sub-award (HHSF22320091006I) through the Harvard Pilgrim Health Care, Inc. for a project entitled "Blood-SCAN Feasibility Evaluation, Phase 3 - Amendment." Total funding will be $33,603.
Shelby Reed of Other Medicine has received a sub-award (327333) through the University of Pennsylvania for a project entitled "Pediatric Crohn's Disease Patient and Provider Risk-Benefit Preferences for Monotherapy versus Combination Therapy." Total funding will be $37,490.
David S. Pisetsky of Rheumatology and Immunology has received an award from the Lupus Research Institute for a project entitled "Determinants of ANA Expression in Patients with SLE." Total funding will be $119,340.
Industry-sponsored clinical trials
James P. Daubert of Cardiology has received an award from Boston Scientific Corporation for a project entitled "BD Star (Daubert)." Total funding will be $60,000.
John K. Harrison of Cardiology has received an award from St. Jude Medical Inc. for a project entitled "ASO 522." Total funding will be $86,300.
Adrian F. Hernandez of Cardiology has received an award from Bayer HealthCare AG for a project entitled "Vericiguat VICTORIA." Total funding will be $1,863,135.
Martin A. Moseley III of Cardiology has received an award from Qualyst Transporter Solutions, LLC for a project entitled "Proteomics and Metabolomics Shared Resource - Qualyst SRA." Total funding will be $21,211.
Robert J. Noveck of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "An open label, single-dose, multi-center, parallel-group, two-staged study to evaluate the pharmacokinetics of the oral cMET inhibitor INC280 in non-cancer subjects with impaired hepatic function and non-cancer subjects with normal hepatic function." Total funding will be $122,719.
Manesh R. Patel of Cardiology has received an award from Medtronic, Inc. for a project entitled "SPYRAL OFF MEDS." Total funding will be $397,475.
Manesh R. Patel of Cardiology has received an award from Medtronic, Inc. for a project entitled "SPYRAL-HTN-ON MED." Total funding will be $376,026.
Matthew T. Roe of Cardiology has received an award from Amgen, Inc. for a project entitled "DMC Think Tank Meeting." Total funding will be $20,000.
Svati H. Shah of Cardiology has received an award from the Bristol-Myers Squibb Company for a project entitled "Heart Failure with Preserved Ejection Fraction (HFPEF): A Systems Biology Approach." Total funding will be $377,069.
Thomas J. Weber of Endocrinology, Metabolism, and Nutrition has received an award from Ultragenyx Pharmaceutical for a project entitled "A Phase 2 Open-Label Trial to Assess the Efficacy and Safety of KRN23, an Antibody to FGF23, in Subjects with Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)." Total funding will be $51,395.
Manal F. Abdelmalek of Gastroenterology has received an award from Galmed Pharmaceuticals Ltd. for a project entitled "A Phase IIb, double blind randomized, controlled clinical trial, to evaluate the efficacy and safety of two aramchol doses versus placebo in patients with Non-Alcoholic Steatohepatitis (NASH)." Total funding will be $241,600.
Manal F. Abdelmalek of Gastroenterology has received an award from Arisaph Pharmaceuticals, Inc. for a project entitled "Ari-3037mo-006 A Randomized, Double-Blind, Exploratory Phase 2 Study To Assess The Effects Of Ariї3037mo On Hepatic Fat Metabolism In Patients With Dysglycemia And Evidence Of Hepatic Steatosis With Nonalcoholic Fatty Liver Disease Or Nonalcoholic St." Total funding will be $115,650.
Anna Mae Diehl of Gastroenterology has received an award from Taiwan J Pharmaceuticals Co. Ltd for a project entitled “A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Phase II trial of JKB-121 for the Treatment of Nonalcoholic Steatohepatitis (NASH).” Total funding will be $250,606.
Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Karyopharm Therapeutics for a project entitled "A Multi-center, phase 1/2 open label study of Selinexor (KPT-330), Lenalidomide, and Dexamethasone in patients with R/R MM." Total funding will be $78,717.
Susanna Naggie of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "A phase3, Open-Label Study to Investigate the Efficacy and Safety of Sofosbuvir/GS-5816 Fixed-Dose Combination for 12 weeks in Subjects with Chronic Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV)-1 Coinfection." Total funding will be $93,445.
Kimberly L. Blackwell of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A Phase III randomized, double-blind, placebo-controlled study of LEE011 or placebo in combination with tamoxifen and goserelin or a non-steroidal aromatase inhibitor (NSAI) and goserelin for the treatment of premenopausal women with hormone receptor." Total funding will be $211,786.
Brent A. Hanks of Medical Oncology has received an award from Merck for a project entitled "Merck Sharp & Dohme Corp. Study Agreement." Total funding will be $478,521.
Neal E. Ready of Medical Oncology has received an award from Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "BMS CA 209-331-001 An Open label, Randomized Phase 3 Study of Nivolumab or Chemo." Total funding will be $160,875.
Richard F. Riedel of Medical Oncology has received an award from Daiichi Pharmaceutical Corporation for a project entitled "A Double-Blind, Randomized, Placebo-Controlled Phase 3 Study of Orally administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath." Total funding will be $130,403.
Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from Genentech, Inc. for a project entitled "Assessing the Impact of a Patient-Clinician Engagement Tool on Patient Reported Outcomes." Total funding will be $125,000.
Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "TRALO - D2210C00007." Total funding will be $197,482.