New funding awards - July 2016

Sponsored Research

Gerald S. Bloomfield of Cardiology has received an award from the The Trustees of Indiana University for a project entitled "Indiana University Intramural Grant - Echocardiographic Image Analysis." Total funding will be $6,267.

Gary M. Felker of Cardiology has received an award from the American Heart Association for a project entitled "Duke Center for the Study of Heart Failure and Diabetes." Total funding will be $1,468,258.

Gary M. Felker of Cardiology has received an award from the American Heart Association for a project entitled "Duke Center for the Study of Heart Failure and Diabetes - Center." Total funding will be $678,309.

Geoffrey S. Ginsburg of Cardiology has received an award (3U01-HG007282-04S1) from the National Institutes of Health for a project entitled "IGNITE Administrative Coordinating Center." Total funding will be $453,438.

Adrian F. Hernandez of Cardiology has received an award (3U10-HL084904-10S1) from the National Institutes of Health for a project entitled "HFN / HIV Supplement." Total funding will be $5,585,098.

Adrian F. Hernandez of Cardiology has received an award from the American Heart Association for a project entitled "Duke Center for the Study of Heart Failure and Diabetes", a part of Gary M. Felker's project entitled "Duke Center for the Study of Heart Failure and Diabetes." Total funding will be $677,923.

Christopher Holley of Cardiology has received an award (7K08-HL114889-05) from the National Institutes of Health for a project entitled "Snornas Are Essential Mediators of Ros Signaling in Cardiovascular Cells." Total funding will be $161,374.

Michel Khouri of Cardiology has received a sub-award (R01-HL119153) through the New York University School of Medicine for a project entitled "International Study of Comparative Health Effectiveness with Medical and Invasive Approaches."

Francis Miller of Cardiology has received an award (1R01-HL130039-01) from the National Institutes of Health for a project entitled "Integrated MiRNA regulation of Nox4 and cellular redox in vascular disease." Total funding will be $1,206,625.

Robert J. Noveck of Cardiology has received an award from the Foundation for the National Institutes of Health for a project entitled "Phase I Study that will Evaluate the Dose Response of a New Preparation of Escherichia coli (E. coli group O 113:H10:K negative) Endotoxin in Healthy Human Volunteers." Total funding will be $235,904.

Eric D. Peterson of Cardiology has received an award from the Society of Thoracic Surgeons for a project entitled "Data Warehousing Center for the Adult Cardiac Surgery, Congenital and Thoracic Databases." Total funding will be $9,023,940.

Svati H. Shah of Cardiology has received an award from the American Heart Association for a project entitled "Duke Center for the Study of Heart Failure and Diabetes", a part of Gary M. Felker's project entitled "Duke Center for the Study of Heart Failure and Diabetes." Total funding will be $559,497.

Andrew J. Muir of Gastroenterology has received a sub-award (HPC-1503-27891) through the University of Florida for a project entitled "The Prioritize Study: A Pragmatic, Randomized Study of Oral Regiments for Hepatitis C: Transforming Decision-Making for Patients, Providers, and Stakeholders." Total funding will be $144,200.

Leigh Boulware of General Internal Medicine has received an award (3UL1-TR001117-04S1) from the National Institutes of Health for a project entitled "Duke CTSA (UL1): Statistical methods for complex data in CV disease research." Total funding will be $423,726.

Susanne B. Haga of General Internal Medicine has received an award (2R01-GM081416-08A1) from the National Institutes of Health for a project entitled "Pharmacogenetic Testing: Challenges of Clinical Integration." Total funding will be $1,482,554.

Shenglan Tang of General Internal Medicine has received an award from the Bill and Melinda Gates Foundation for a project entitled "Supporting the National Scale-up of an Innovative Program to improve TB Control in China." Total funding will be $1,199,997.

James A. Tulsky of General Internal Medicine has received an award through the Mount Sinai School of Medicine for a project entitled "A Research Agenda for Communication in Serious Illness." Total funding will be $19,972.

John Williams of General Internal Medicine has received a sub-award through Oregon Health & Science University for a project entitled "Peer Review of PCORI's Funded Research." Total funding will be $31,808.

J. Brice Weinberg of Hematology has received an award from the Burroughs Wellcome Fund for a project entitled "Burroughs Wellcome Travel Fund-Assessment of endothelial glycocalyz in normal children in a malaria endemic area of Africa." Total funding will be $8,000.

John A. Bartlett of Infectious Diseases has received a sub-award (D43TW010138) through the Kilimanjaro Christian Medical Centre for a project entitled "MEPI Tanzania." Total funding will be $369,842.

Mehri McKellar of Infectious Diseases has received an award from Alliance Behavioral Healthcare for a project entitled "HIV Early Intervention Testing." Total funding will be $119,850.

Matthew P. Rubach of Infectious Diseases has received an award (1K23-AI116869-01A1) from the National Institutes of Health for a project entitled "Viral Zoonoses and Severe Febrile Illness in Northern Tanzania." Total funding will be $743,000.

Michael A. Hauser of Medical Genetics has received an award from Cohen Veterans Bioscience for a project entitled "PTSD GWAS." Total funding will be $31,164.

Megan A. McNamara of Medical Oncology has received an award from the V Foundation for Cancer Research for a project entitled "An IND-enabling Trial to Determine the Number and Volume of Injections Necessary for Adequate Distribution throughout Cancer Metastases and to Validate Poliovirus Receptor (CD155) Expression in Prostate Cancer." Total funding will be $200,000.

Lesley H. Curtis of Other Medicine has received a sub-award (1U01-HL130114-01) through the University of Washington for a project entitled "CHS." Total funding will be $63,280.

Kevin A. Schulman of Other Medicine has received an award from the Private Sector Health Alliance of Nigeria for a project entitled "Education Program for PHN." Total funding will be $17,655.

Megan E. Clowse of Rheumatology and Immunology has received an award through the University of California - San Francisco for a project entitled "An Investigator-Initiated, Phase II, Randomized, Withdrawal Study of Mycophenolate Mofetil (MMF) in Patients with Stable, Quiescent Systemic Lupus Erythematosus (SLE)." Total funding will be $30,943.

Donghai Wang of Rheumatology and Immunology has received an award (7R01-AI110695-02) from the National Institutes of Health for a project entitled "Censoring Inflammation by Protein Geranylgeranylation." Total funding will be $1,684,046.

Industry-sponsored Clinical Trials

Raymond J. Kim of Cardiology has received an award from Chiltern International Inc. for a project entitled "A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Effects of Multiple Subcutaneous Injections of Elamipretide on Left Ventricular Function in Subjects with Stable Heart Failure with Reduced Ejection Fraction." Total funding will be $347,059.

L. Kristin Newby of Cardiology has received an award from the Baseline Study LLC for a project entitled "Baseline Study." Total funding will be $24,910,523.

Eric Velazquez of Cardiology has received an award from Bay Labs, Inc. for a project entitled "Deep Learning in Echocardiography." Total funding will be $25,858.

Andrew Wang of Cardiology has received an award from MyoKardia, Inc. for a project entitled "MyoKardia HCM App." Total funding will be $175,607.

Manal F. Abdelmalek of Gastroenterology has received an award from GENFIT for a project entitled "Genfit GFT505-315-1 NASH - A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy adn Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis." Total funding will be $290,604.

Deborah A. Fisher of Gastroenterology has received an award from Eli Lilly and Company for a project entitled "A Phase 4 Study of Efficacy and Safety of Dulaglutide When Added to Insulin Treatment With or Without Oral Antidiabetic Medication in Patients With Type 2 Diabetes: Protocol # H9X-JE-GBGF." Total funding will be $184,347.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from AbbVie Inc. for a project entitled "Phase III double blind study of Bortezomib and Dex in combination with Venetoclax or Placebo in R/R MM." Total funding will be $993,528.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Randomized Phase II trial study of lenalidomide, bortezomib and dexamethsone (RVD) with or without Panobinostat in new MM pts." Total funding will be $387,720.

Thomas L. Ortel of Hematology has received an award from Stago for a project entitled "Precision Performance of STA®-COAG Control (N + Abn) Plus On Sta -Satellite®." Total funding will be $21,800.

Vance G. Fowler of Infectious Diseases has received an award from Karius, Inc. for a project entitled "Diagnosis of Bacteremia/Septicemia by the Karius sequencing-based Infectious disease diagnostic assay." Total funding will be $112,487.

Cameron R. Wolfe of Infectious Diseases has received a sub-award (HHSN261200800001E) through Social & Scientific Systems, Inc. for a project entitled "CRB-SSS-S-16-004809 - Protocol IRC 003- TO#Q7." Total funding will be $7,500.

Kimberly L. Blackwell of Medical Oncology has received an award from Genentech, Inc. for a project entitled "Genentech Breast Cancer Practicum." Total funding will be $80,000.

Jeffrey Crawford of Medical Oncology has received an award from Bayer HealthCare AG for a project entitled "Phase II anetumab ravtansine as 2nd line treatment for malignant pleural mesothelioma." Total funding will be $231,057.

Herbert I. Hurwitz of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "An open label multicenter dose escalation and expansion phase IB study to evaluste the safety pharmacokinetics and therapeutic activity." Total funding will be $833,039.

Andrew B. Nixon of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "The role of Claudin-2 in metastatic colorectal cancer." Total funding will be $180,666.

Hope E. Uronis of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A Randomized multicenter double blind Phase III study of Nivolumab or placebo in subjects with resected esophageal junction cancer." Total funding will be $276,065.

Gordana Vlahovic of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A randomized phase 3 Open label study of Nivolumab vs Temozolomide each in combination with radiation therapy in newly diagnosed adult subjects with unmethylated MGMT glioblastoma (CA209-498)." Total funding will be $198,811.

Gordana Vlahovic of Medical Oncology has received an award from Eli Lilly and Company for a project entitled "A Phase 1b/2 Dose Escalation and Cohort Expansion Study of the Safety, Tolerability and Efficacy of a Novel Transforming Growth Factor-beta Receptor I Kinase Inhibitor Administered with Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumours." Total funding will be $403,216.

Alice L. Gray of Pulmonary, Allergy, and Critical Care Medicine has received an award from PTC Therapeutics, Inc for a project entitled "A phase 3 extension study of ataluren (PTC124) in patients with nonsense mutation cystic fibrosis." Total funding will be $80,309.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Nintedanib for the Prevention and Treatment of Bronchiolitis Obliterans (BO)." Total funding will be $219,102.

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