Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
[tabs style="vertical"] [tab title="Sponsored research"]Richard C. Becker of Cardiology has received an award (1U54-HL112307-01) from the National Institutes of Health for a project entitled "TRC-THD Administrative Coordinating Center (ACC)." Total funding will be $232,299.
Gary M. Felker of Cardiology has received an award (1R01-HL105448-01A1) from the National Institutes of Health for a project entitled "GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC)." Total funding will be $13,752,121.
Sarah B. Frazier (Mentor: Christopher Kontos) of Cardiology has received an award from the American Heart Association for a project entitled "The role of Caskin2 in endothelial biology." Total funding will be $46,000.
Neil J. Freedman of Cardiology has received an award from the American Heart Association for a project entitled "Anti-atherogenic mechanisms of G protein-coupled receptor kinase-5." Total funding will be $154,000.
Patrick M. Hranitzky of Cardiology has received an award from the Duke Clinical Research Institute for a project entitled "Catheter Ablation for Ventricular Tachycardia in Patients with an Implantable Cardioverter Defibrillator (CALYPSO)." William E. Kraus of Cardiology has received a sub-award (HHSN263200700030C) through KAI Research, Inc. for a project entitled "HHS-N-263-2007-00030-C: KAI subcontract CALERIE Public Dataset Ancillary Study." Total funding will be $115,937.
Daniel B. Mark of Cardiology has received an award (1R01-HL105457-01A1) from the National Institutes of Health for a project entitled "Guiding Evidence Based Therapy Using Biomarker Intensified Treatment (EQOL)." Total funding will be $1,098,935.
Daniel B. Mark of Cardiology has received a sub-award (U01-HL092607-) through Mount Sinai Hospital for a project entitled "Economics & Quality of Life in the TACT study." Total funding will be $72,030.
Jessica L. Reinardy (Mentor: Christopher Kontos) of Cardiology has received an award from the American Heart Association for a project entitled "The role of Akt-mediated phosphorylation on Tie1 function." Total funding will be $46,000.
Matthew T. Roe of Cardiology has received an award from the American Heart Association for a project entitled "Mission Lifeline." Total funding will be $253,496.
Jonathan A. Stiber of Cardiology has received an award from the American Heart Association for a project entitled "Role of Drebrin in Vascular Smooth Muscle Remodeling." Total funding will be $154,000.
Andrew Wang of Cardiology has received an award from the American Heart Association for a project entitled "A Prospective, Multicenter Evaluation of Contemporary Treatment of Infective Endocarditis." Total funding will be $145,863.
Lisheng Zhang of Cardiology has received an award from the American Heart Association for a project entitled "Atherogenic Mechanisms of the Dual RhoGEF Kalirin." Total funding will be $154,000.
Anna Mae Diehl of Gastroenterology has received an award (2R01-DK077794-05A1) from the National Institutes of Health for a project entitled "Hedgehog Signaling and Adult Liver Regeneration." Total funding will be $1,365,900.
Hayden B. Bosworth of General Internal Medicine has received an award from NHS Direct for a project entitled "The Healthlines Study." Total funding will be $50,067.
Harvey Jay Cohen of Geriatrics has received an award from the John A. Hartford Foundation, Inc. for a project entitled "John A. Hartford Foundation's Centers of Excellence (CoE)." Total funding will be $30,000.
G. Ralph Corey of Infectious Diseases has received a sub-award (HHSN272201000043C) through the University of Florida for a project entitled "Targeted Clinical Trials to Reduce the Risk of Antimicrobial Resistance." Total funding will be $293,589.
Vance G. Fowler Jr. of Infectious Diseases has received a sub-award (7R01-AI077706-03) through the University of Texas Southwestern Medical Center for a project entitled "Immune System Biological Networks: Case Study." Total funding will be $67,673.
Daian Chen (Mentor: Thomas M. Coffman) of Nephrology has received an award from the American Heart Association for a project entitled "The Role of AT1A Receptors in the Collecting Duct in Hypertension and Blood Pressure Control." Total funding will be $82,000.
Thomas M. Coffman of Nephrology has received an award (2T32-DK007731-16A1) from the National Institutes of Health for a project entitled "Duke Training Grant in Nephrology." Total funding will be $962,000.
Maria M. Herrera of Nephrology has received an award (1K99-HL109167-01A1) from the National Institutes of Health for a project entitled "Renal Endothelin-1: Control of Sodium Excretion and Blood Pressure." Total funding will be $177,000.
Laura P. Svetkey of Nephrology has received an award (3U01-HL096720-04S1) from the National Institutes of Health for a project entitled "Cell Phone Intervention for Young Adults - Diversity Supplement." Total funding will be $83,152.
Jiandong Zhang (Mentor: Steven D. Crowley) of Nephrology has received an award from the American Heart Association for a project entitled "Macrophage AT1 Receptors Regulate Hypertensive Kidney Injury via An IL-1-dependent Pathway." Total funding will be $82,000.
Bradley J. Kolls of Neurology has received a sub-award (1R43-NS076045-01A1) through Optima Neuroscience, Inc for a project entitled "Validation of a Novel Automated Seizure Detection and EEG Trending System for Continuous Brain Monitoring in the ICU." Total funding will be $36,677.
Nicole M. Kuderer of Medical Oncology has received an award from the Baylor College of Medicine for a project entitled "A neoadjuvant study of extended lapatinib and trastuzumab with or without endocrine therapy in locally advanced HER2-overexpressing breast cancer patients."
Jeffrey Peppercorn of Medical Oncology has received an award from the American Cancer Society for a project entitled "Impact of Benefits Structure and Outreach on Screening Mammography Utilization." Total funding will be $531,010.
Victoria L. Seewaldt of Medical Oncology has received an award from the Susan G. Komen Breast Cancer Foundation for a project entitled "Community Based Breast MRI Screening." Total funding will be $72,117.[/tab] [tab title="Industry-sponsored clinical trials"]Tristram D. Bahnson of Cardiology has received an award from Sanofi-Aventis U.S. for a project entitled "Introduction to Atrial Fibrillation-MULTAQ Clinical Experience Practicum." Total funding will be $77,900.
Tristram D. Bahnson of Cardiology has received an award from CardioFocus, Inc. for a project entitled "Pivotal Clinical Study of the CardioFocus Endoschopic Ablation System - Adaptive Contact (EAS-AC) or HEARTLIGHT for the Treatment of Symptomatic Atrial Fibrillation."
Michael A. Blazing of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A randomized, double blind, placebo controlled study to assess the efficacy of LCQ908 on cardiovascular risk." Total funding will be $559,044.
Terry A. Fortin of Cardiology has received an award from the United Therapeutics Corporation for a project entitled "Retro Obser study of Pul Hypertension Patients dosed with > 216mcg/day of Tyvaso Inhale solution."
Patrick M. Hranitzky of Cardiology has received an award from Hansen Medical for a project entitled "A prospective, randomized study of the Hansen System for introducing and positioning the ThermoCool catheter in patients with atrial fibrillation."
Robert J. Noveck of Cardiology has received an award from Reata Pharmaceuticals, Inc. for a project entitled "Study of Bardoxolone Methyl in subjects with mild, moderate and Normal hepatic function." Total funding will be $29,250.
John R. Guyton of Endocrinology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "A Phase 2, Open-label Extension of Study R727-CL-1003 to Evaluate the Long-Term Safety and Efficacy of REG727 Administered Subcutaneous Injection in Patients with Heterozygous Familial Hypercholesterolemia, Protocol No. R727-CL-1032." Keyur Patel of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-334-0110 Study of GS-977 with additives on Chronic Genotype 1,4,5, or 6 HCV Infection."
Keyur Patel of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS US 334 0109 study of GS-7977 & Ribavirin on HCV." Karen E. Steinhauser of General Internal Medicine has received an award from the HealthCare Chaplaincy, Inc. for a project entitled "Caregiver Outlook: An Evidence-based Intervention for the Chaplain Toolkit." Total funding will be $246,046.
Charles B. Hicks of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "Treatment of Acute HIV Infection with the Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate [Quad FDC Tablet], A Pilot Study of Response to Therapy an HIV Pathogenesis, (PHI-4 Quad Study)."
Melissa D. Johnson of Infectious Diseases has received an award from Charles River Laboratories International, Inc. for a project entitled "Repository Collection - Charles River." Total funding will be $135,867.
Annick Desjardins of Neurology has received an award from Genentech, Inc. for a project entitled "Review of Patients with Glioblastoma Treated with Avastin-Based Therapy." Total funding will be $350,970.
Annick Desjardins of Neurology has received an award from Aldagen Inc. for a project entitled "A Pilot Safety Study of the Administration of Bone Marrow Derived Stem Cells (ALD-451) in WHO grade IV Malignant Glioma."
Bradley J. Kolls of Neurology has received an award from UCB Pharma, Inc. for a project entitled "Utility of Intravenous Lacosamide Compared with Fosphenytoin in the Treatment of Patients with Frequent Nonconvulsive Seizures."
Kimberly L. Blackwell of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Multicenter randomized db, placebo controlled, PII trial evaluating the safety & efficacy TKI258 comb w/ fulvestrant, in postmen patients w/ HER2- and HR+ breast cancer that have evidence of disease progression on or after prior endocrine therapy."
Michael R. Harrison of Medical Oncology has received an award from Exelixis, Inc for a project entitled "A Phase 3, randomized, double-blind, controlled trial of cabozantinib (XL184) vs. mitoxantrone plus prednisone in men with previously treated symptomatic castration-resistant prostate cancer."
April K. Salama of Medical Oncology has received an award from the GlaxoSmithKline for a project entitled "A phase III, randomized, open-label study comparing the combination of the BRAF inhibitor, dabrafenib and the MEK inhibitor trametinib to the BRAF inhibitor vemurafenib in subjects with unresectable (stage IIIc) or metastatic (stage IV) BRAF V600E/K."
James J. Vredenburgh of Medical Oncology has received an award from the Celldex Therapeutics, Inc. for a project entitled "A Phase II Study of Rindopepimut/GM-CSF in Patients with Relapsed EGFRvIII-Positive Glioblastoma. CDX110-06. The "ReACT" Study."
Scott M. Palmer of Pulmonary has received an award from the CSL Behring LLC for a project entitled "Hypogammaglobulinemia in Lung Transplant Recipients: Prevalence, Risk Factors, and Long-term Patient Outcomes."[/tab] [/tabs]