New funding awards - March 2015

Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.

Sponsored research

Eric D. Peterson of Cardiology has received an award from the The Clinical Research Forum for a project entitled "CRF Programs for the National Clinical and Translational Research Enterprise." Total funding will be $249,362.

Geoffrey Pitt of Cardiology has received an award from the Simons Foundation Autism Research Initiative for a project entitled "SCN2A mouse." Total funding will be $60,000.

Gillian D. Schmidler of Cardiology has received an award (HHSA290201500004I-TO1) from the Agency for Healthcare Research and Quality for a project entitled "EPC V Admin Task TO1." Total funding will be $275,000.

Tracy Y. Wang of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "ACC Championing Care Registry." Total funding will be $229,669.

Mary E. Klotman has received an award (1P01-AI110485-01A1) from the National Institutes of Health for a project entitled "NHP Core for Development of an Integrase Defective Lentiviral Vector HIV Vaccine."

Mary E. Klotman has received an award (1P01-AI110485-01A1) from the National Institutes of Health for a project entitled "Safety and Durability of Integrase Defective Lentiviral Vector for an HIV Vaccine."

Mary E. Klotman has received an award (1P01-AI110485-01A1) from the National Institutes of Health for a project entitled "Administrative Core." Total funding will be $8,990,219.

James R. Bain of Endocrinology, Metabolism, and Nutrition has received a sub-award (2P01-DK078669-06B1) through Washington University for a project entitled "Metagenomic Studies of the Gut Microbiomes of Obese and Lean Twins." Total funding will be $224,903.

Deborah Muoio of Endocrinology, Metabolism, and Nutrition has received an award (2R01-DK089312-05) from the National Institutes of Health for a project entitled "Role of Carnitine Acetyltransferase in Mitochondrial and Metabolic Function." Total funding will be $1,990,550.

Diego Bohorquez of Gastroenterology has received an award from the American Gastroenterological Association for a project entitled "Appetite, Obesity and a Gut Neuroepithelial Circuit." Total funding will be $25,000.

Rowena J. Dolor of General Internal Medicine has received a sub-award (1U34-AR065739-01A1) through Oregon Health & Science University for a project entitled "Community-based Assessment of Skin Care, Allergies and Eczema (CASCADE)." Total funding will be $5,000.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received a sub-award (N00014-14-1-0848) through the National Marrow Donor Program for a project entitled "RITN."

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award (HHSO100201000001C-Option5) from the Department of Health and Human Services for a project entitled "Point of Care Biodosimeter." Total funding will be $10,400,000.

Rebekah W. Moehring of Infectious Diseases has received an award from the CDC Foundation for a project entitled "Patient Tools for Antibiotic Stewardship Programs." Total funding will be $407,250.

Rebekah W. Moehring of Infectious Diseases has received an award (1K08-HS023866-01) from the Agency for Healthcare Research and Quality for a project entitled "Defining Measures of Impact for Antimicrobial Stewardship Programs in Community Hospitals." Total funding will be $738,574.

Jason E. Stout of Infectious Diseases has received a sub-award (1U52-PS004698-) through the NC Department of Health and Human Services for a project entitled "Epidemiology/General Communicable Disease Control." Total funding will be $85,933.

Brent A. Hanks of Medical Oncology has received a sub-award (5U01-CA154967-05) through the Fred Hutchinson Cancer Research Center for a project entitled "A Phase II, Open-label, Multicenter, Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant Human Fit3 Ligand."

Jennifer J. Huang (Mentor: Gerard C. Blobe) of Medical Oncology has received an award (1F30-CA196162-01) from the National Institutes of Health for a project entitled "Role of Type III TGF-beta Receptor Shedding in Lung Cancer Initiation and Progression." Total funding will be $89,544.

Arif H. Kamal of Medical Oncology has received a sub-award (17845) through the American Society of Clinical Oncology for a project entitled "Integrating Palliative Care in Oncology Practice." Total funding will be $18,500.

John W. Stanifer (Mentor: Uptal Patel) of Nephrology has received an award from the American Kidney Fund for a project entitled "Health Literacy and Social Determinants among Individuals with Chronic Kidney Disease in an Underserved Community." Total funding will be $159,220.

Laura P. Svetkey of Nephrology has received a sub-award (1R01-HL122144-01A1) through the University of Pittsburgh for a project entitled "Identifying Strategies for Effective Weight Management in Diverse Interventions." Total funding will be $40,310.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (2U01-AI063594-11) through the Mount Sinai School of Medicine for a project entitled "CTOT Ancillary Studies Fund." Total funding will be $250,000.

Claude A. Piantadosi of Pulmonary, Allergy, and Critical Care Medicine has received an award (2T32-HL007538-31A1) from the National Institutes of Health for a project entitled "Interdisciplinary Training Program in Lung Disease." Total funding will be $2,157,280.

Industry-sponsored clinical trials

Christopher Granger of Cardiology has received an award from Daiichi Sankyo Inc for a project entitled "IMPACT AF Daiichi." Total funding will be $600,000.

Adrian F. Hernandez of Cardiology has received an award from Janssen Pharmaceutica, Inc. for a project entitled "ARAMIS Registry (Janssen)." Total funding will be $2,637,189.

Robert J. Mentz of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Angina Pectoris in Diabetic Patients." Total funding will be $59,433.

Robert J. Mentz of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Insights from HF-ACTION." Total funding will be $87,494.

Robert J. Noveck of Cardiology has received an award from Pfizer, Inc. for a project entitled "A3921252 Immune Cell Function Study in Healthy Volunteers." Total funding will be $375,606.

Manesh R. Patel of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Patient Reported Preferences Affecting Revascularization Decisions." Total funding will be $61,880.

Jonathan P. Piccini of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "GD-Star -- Atrial Ischemia in AF." Total funding will be $39,992.

Matthew T. Roe of Cardiology has received an award from Daiichi Sankyo Inc for a project entitled "LOI - DU-176b AF PCI Trial (Edoxaban)." Total funding will be $1,137,874.

Zainab Samad of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "Ventricular Remodeling in Transcatheter Aortic Valve Replacement versus Surgical Aortic Valve Replacement." Total funding will be $94,990.

Pierluigi Tricoci of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia Undergoing Lipid Apheresis Therapy R727-CL-1216." Total funding will be $234,763.

Thomas J. Weber of Endocrinology, Metabolism, and Nutrition has received an award from Ultragenyx Pharmaceutical for a project entitled "A Phase 2b, Open-Label, Long-Term Extension Study to Evaluate the Safety and Pharmacodynamics of KRN23 in Adult Subjects with X-Linked Hypophosphatemia (XLH)." Total funding will be $78,551.

Andrew J. Muir of Gastroenterology has received an award from AbbVie Inc. for a project entitled "AbbVie M14-868 A Randomized, Open-label multicenter study to evaluate the efficacy, safety, and pharmacokinetics of co-administration of ABT-493 and ABT-530 with and without RBV in subjects with chronic hepatitis C virus (HCV) Genotype 2 or Genotype." Total funding will be $147,180.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award from Jazz Pharmaceuticals for a project entitled "Defibrotide for the prevention of GVHD." Total funding will be $94,987.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from AbbVie Inc. for a project entitled "A Phase I Study of ABT-199 Monotherapy in R/R Multiple Myeloma." Total funding will be $386,307.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from MacroGenics, Inc. for a project entitled "A Phase 1, First-in-Human, Dose Escalation Study of MGD006, a CD 123 X CD3 Dual Affinity Re-Targeting (DART) Bi-Specific Antibody-Based Molecule, in Patients with Relapsed or Refractory Acute Myeloid Leukemia." Total funding will be $530,058.

Marilyn J. Telen of Hematology has received an award from Pfizer, Inc. for a project entitled "PFIZER B0401016." Total funding will be $334,481.

Susanna Naggie of Infectious Diseases has received an award from Institute for Medical Research, Inc. for a project entitled "PSA- Sara Hoffman- SONOT." Total funding will be $25,685.

Susanna Naggie of Infectious Diseases has received an award from the Institute for Medical Research, Inc. for a project entitled "PSA- Sara Hoffman- Valor." Total funding will be $15,441.

Lesley H. Curtis of Other Medicine has received an award from Gilead Sciences, Inc. for a project entitled "Antiarrhythmic Medications for ICM." Total funding will be $89,756.

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