New funding awards - March 2018

Sponsored Research

Elizabeth Finch of Cardiology has received an award (R21-AG058214-01A1) from the National Institutes of Health for a project entitled "Better than Drugs: Neuroprotection By Exercise in a Mouse Model of Menopause in Alzheimer's Disease." Total funding will be $239,625.

Robert J. Mentz of Cardiology has received an award (5U10-HL084904-11) from the National Institutes of Health for a project entitled "Subcutaneous Furosemide in Acute Decompensated Heart Failure."

Eric D. Peterson of Cardiology has received an award from the American Heart Association for a project entitled "Get With the Guidelines Registry." Total funding will be $1,272,071.

Matthew Kappus of Gastroenterology has received a sub-award through the University of California - San Francisco for a project entitled "Development of a multi-center research infrastructure for the Strength Training Intervention (STRIVE) for liver transplant candidates." Total funding will be $22,000.

Omobonike O. Oloruntoba of Gastroenterology has received an award through the University of Texas - Southwestern for a project entitled "DAA-HCC - UT Southwestern." Total funding will be $20,111.

Rowena J. Dolor of General Internal Medicine has received a sub-award (1R01-HL136682-01) through the Weill Medical College of Cornell University for a project entitled "The CAPTURE Study: Validatiing a unique COPD screening tool in primary care." Total funding will be $111,300.

Christopher B. Bowling of Geriatrics has received an award (7R01-HL133618-02) from the National Institutes of Health for a project entitled "Sustained blood pressure control and progression of multimorbidity." Total funding will be $1,953,754.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award through the National Marrow Donor Program for a project entitled "RITN2018." Total funding will be $8,000.

Sandeep Dave of Hematological Malignancies and Cellular Therapy has received an award from the Lymphoma Research Foundation of America for a project entitled "Genomic Predictors of Response in Mantle Cell Lymphoma." Total funding will be $125,000.

Jennifer R. Shingleton (Mentor: Sandeep Dave) of Hematological Malignancies and Cellular Therapy has received an award from the Lymphoma Research Foundation of America for a project entitled "The Tumor Suppressive Role of ID3 in Burkitt Lymphoma." Total funding will be $50,000.

Jennifer R. Shingleton (Mentor: Sandeep Dave) of Hematological Malignancies and Cellular Therapy has received an award from the Lymphoma Research Foundation of America for a project entitled "Roles of SETD2 in non-Hodgkin lymphomas."

Anthony D. Sung of Hematological Malignancies and Cellular Therapy has received an award from the Damon Runyon Cancer Research Foundation for a project entitled "Personalized Prebiotics to Optimize Microbiota Metabolism and Improve Transplant Outcomes." Total funding will be $150,000.

John Strouse of Hematology has received a sub-award (1U1-EMC31108-01-00) through the Carolinas HealthCare System for a project entitled "Education and Mentoring to BRing Access to CarE SCD - EMBRACE SCD." Total funding will be $84,834.

Ewa M. Wysokinska of Hematology has received a sub-award through the Academic and Community Cancer Research United for a project entitled "Phase III of two doses of Apixaban for secondary preventation of cancer related VT." Total funding will be $130,750.

Vance G. Fowler Jr. of Infectious Diseases has received an award (5UM1-AI104681-03) from the National Institutes of Health for a project entitled "ARLG Administrative Supplement." Total funding will be $1,286,280.

Myaing M. Nyunt of Infectious Diseases has received an award (7U19-AI129386-02) from the National Institutes of Health for a project entitled "RP3", a part of Christopher V. Plowe's project entitled "International Centers of Excellence for Malaria Research." Total funding will be $794,771.

Myaing M. Nyunt of Infectious Diseases has received an award (7U19-AI129386-02) from the National Institutes of Health for a project entitled "Mapping Core", a part of Christopher V. Plowe's project entitled "International Centers of Excellence for Malaria Research." Total funding will be $237,081.

Myaing M. Nyunt of Infectious Diseases has received an award (7U19-AI129386-02) from the National Institutes of Health for a project entitled "RP1", a part of Christopher V. Plowe's project entitled "International Centers of Excellence for Malaria Research." Total funding will be $625,083.

Myaing M. Nyunt of Infectious Diseases has received a sub-award through Population Services International for a project entitled "Malaria elimination effort among mobile migrant plantation workers in Cambodia and Myanmar." Total funding will be $53,181.

Christopher V. Plowe of Infectious Diseases has received an award (7U19-AI129386-02) from the National Institutes of Health for a project entitled "Admin Core." Total funding will be $4,246,888.

Christopher V. Plowe of Infectious Diseases has received an award (7U19-AI129386-02) from the National Institutes of Health for a project entitled "RP2." Total funding will be $577,034.

Megan E. Reller of Infectious Diseases has received a sub-award through the University of North Carolina - Chapel Hill for a project entitled "Zika Diagnostics Development: Diagnosing recent and remote Zika infections." Total funding will be $90,000.

Thomas Stinchcombe of Medical Oncology has received an award from Molecular Partners AG for a project entitled "A Phase 1b/2, single-arm, open-label, multi-center study of MP0250 in combination with osimertinib in patients with EGFR-mutated non-squamous non-small cell lung cancer (NSCLC) pretreated with osimertinib." Total funding will be $166,308.

Allison E. Ashley-Koch of Nephrology has received a sub-award through the University of Connecticut for a project entitled "Genome-wide Association Analysis in the Neurocognitive Outcomes of Depression in the Elderly (NCODE) data set." Total funding will be $79,214.

Timothy Scialla of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (PCS-1504-30430) through the University of Illinois at Chicago for a project entitled "RofLumilast or Azithromycin to preveNt COPD Exacerbations (RELIANCE)." Total funding will be $7,000.

Ankoor Shah of Rheumatology and Immunology has received a sub-award (5UM1-AI109565-05) through the Benaroya Research Institute at Virginia Mason for a project entitled "Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis: A Phase I/II Multicenter, Randomized, Double-Blinded Safety Study." Total funding will be $52,410.

Industry-sponsored Clinical Trials

Karen P. Alexander of Cardiology has received an award from Sanofi US for a project entitled "EFPEG Non-Outcomes Studies." Total funding will be $1,168,011.

Gary M. Felker of Cardiology has received an award from Cytokinetics, Inc. for a project entitled "Cytokinetics Phase III." Total funding will be $163,357.

Ravi Karra of Cardiology has received an award from MyoKardia, Inc. for a project entitled "Oral Doses of MYK-491 in Patients with Stable Heart Failure." Total funding will be $387,050.

Renato D. Lopes of Cardiology has received an award from Sanofi US for a project entitled "Sanofi SOTA Outcomes EFC15156." Total funding will be $3,686,877.

Martin A. Moseley III of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Analysis of Hepatic Tissues using Tandem Mass Spectrometry and the Biocrates p180 Kit." Total funding will be $10,351.

Jonathan P. Piccini of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "Multiple Cardiac Sensors for Management of Heart Failure." Total funding will be $140,869.

Sudarshan Rajagopal of Cardiology has received an award from the United Therapeutics Corporation for a project entitled "Restrospective Study of Outcomes of Patients with WHO Groups 1 and 3 Pulmonary Hypertension Treated with High-Dose Inhaled Treprostinil." Total funding will be $93,536.

Matthew T. Roe of Cardiology has received an award from Sanofi US for a project entitled "Odyssey Outcomes Legacy." Total funding will be $6,100,335.

Christopher R. Walters of Cardiology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Care OptimizatioN through PatieNt and hospital Engagement Clinical Trial for Heart Failure." Total funding will be $44,353.

Deborah A. Fisher of Gastroenterology has received an award from Eli Lilly and Company for a project entitled "H9X-MC-GBGL." Total funding will be $300,160.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "Clinical Presentation, Treatment, and Outcomes of Grade 2-4 Acute Graft Versus Host Disease (GVHD) Patients after Allogeneic Hematopoietic Stem Cell Transplants (HSCT): A Multi-Center Chart Audit Study." Total funding will be $91,400.

Matthew S. McKinney of Hematological Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "A Phase 2, Open-Label, 2-Cohort, Multicenter Study of INCB050465, a PI13K Inhibitor, in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a BTK Inhibitor (CITADEL-205)." Total funding will be $258,814.

Anthony D. Sung of Hematological Malignancies and Cellular Therapy has received an award from Enterome, Inc for a project entitled "Evaluation of the effect of EB8018 on an acute murine model of GvHD." Total funding will be $17,500.

Nirmish R. Shah of Hematology has received an award from Pfizer, Inc. for a project entitled "Open Label study to evaluate the safety and Pharmacokinetics of PF-06412528 in children 7-17 for treatment of moderate to severe pain." Total funding will be $105,359.

Nirmish R. Shah of Hematology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Phase II study to assess SEG101 in Sickle Cell Patients." Total funding will be $899,109.

Gregory Gray of Infectious Diseases has received an award from Kirkland Biosciences LLC for a project entitled "Detection of Dengue, Chikungunya and Zika Viruses by a New Multiplexing Platform among Patients in Sarawak, Malaysia." Total funding will be $20,000.

Michael A. Morse of Medical Oncology has received an award from Halozyme, Inc. for a project entitled "A Phase 1b, Randomized, Open-Label Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) in Combination With Cisplatin Plus Gemcitabine and PEGPH20 in Combination With Atezolizumab and Cisplatin Plus Gemcitabine Compared With Cisplatin Plus Ge." Total funding will be $475,316.

Neal E. Ready of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "A Multicenter, Open-Label, Phase 1b/2 Study To Evaluate Safety And Efficacy Of Avelumab Msb0010718c) In Combination With Chemotherapy With Or Without Other Anti-Cancer Immunotherapies As First-Line Treatment In Patients With Advanced Malignancies." Total funding will be $443,282.

Richard F. Riedel of Medical Oncology has received an award from Oncternal Therapeutics, Inc. for a project entitled "A Phase 1, Dose Escalation Study of Intravenous TK216 in Patients with Relapsed or Refractory Ewing Sarcoma." Total funding will be $377,911.

Tian Zhang of Medical Oncology has received an award from Janssen Pharmaceutical, Inc. for a project entitled "A Salvage Trial of AR Inhibition with ADT and Apalutamide with Docetaxel followed by Radiation Therapy in Men with PSA Recurrent Prostate Cancer after Radical Prostatectomy (їSTARTARї)." Total funding will be $543,567.

Patricia Lugar of Pulmonary, Allergy, and Critical Care Medicine has received an award from Biocryst Corporation for a project entitled "BCX7353-302:Phase 3 randomized doubleblind placebo controlled parallel group study evaluate efficacy&safety of 2-dose levels BCS7353 as oral treatment for prevention of attacks w/hereditary angioedema." Total funding will be $103,846.

Neil R. MacIntyre of Pulmonary, Allergy, and Critical Care Medicine has received an award from Teleflex, Inc. for a project entitled "Effects of Teleflex Catheter on Ventilator Mechanics." Total funding will be $48,972.

Kamran Mahmood of Pulmonary, Allergy, and Critical Care Medicine has received an award from Olympus Corporation for a project entitled "Current Trends in Pleural Disease Management -- 2018." Total funding will be $4,000.

Megan E. Clowse of Rheumatology and Immunology has received an award from GlaxoSmithKline for a project entitled "Get on Board: Enabling open and honest conversations about pregnancy planning and lupus." Total funding will be $405,611.

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