New funding awards - May 2013

By etm18@dhe.duke.edu
Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards. [tabs style="vertical"][tab title="Sponsored research"]Chiara Melloni of Cardiology has received an award (HHSN275201000003I-TO4) from the National Institutes of Health for a project entitled "PTN Task Order #4: Hydroxyurea PK Extension." Total funding will be $190,187. Robert J. Noveck of Cardiology has received a sub-award (N66001-10-C-2134) through the University of Colorado - Denver for a project entitled "GQ2 High Altitude." Total funding will be $235,813. Chetan B. Patel of Cardiology has received a sub-award (UAB discretionary funds) through the University of Alabama at Birmingham for a project entitled "The Medical Arm of Mechanical Circulatory Support Study." Total funding will be $32,963. Howard A. Rockman of Cardiology has received an award from the North Carolina Biotechnology Center for a project entitled "Echocardiography for Sophisticated Murine Cardiac Phenotyping." Total funding will be $194,002. Eugene Z. Oddone of General Internal Medicine has received an award (HHSN275201300198P) from the National Institutes of Health for a project entitled "Develop Training in the principles, methods, and ethics of clinical research under the Clinical Research Reproductive Scientist Training (CREST)." Total funding will be $20,000. Eugene Z. Oddone of General Internal Medicine has received an award (HHSN275201300172P) from the National Institutes of Health for a project entitled "Develop Training in the principles, methods, and ethics of clinical research under the Clinical Research Reproductive Scientist Training (CREST)." Total funding will be $20,000. John P. Chute of Hematological Malignancies and Cellular Therapy has received an award (1U01-AI107333-01) from the National Institutes of Health for a project entitled "Epidermal growth factor mitigates radiation-induced hematopoietic failure." Total funding will be $2,652,541. Anthony D. Sung (Mentor: Nelson J. Chao) of Hematological Malignancies and Cellular Therapy has received an award from the American Society of Hematology for a project entitled "Memory T Cells in Allogeneic Hematopoietic Stem Cell Transplantation." Total funding will be $50,000. Grace M. Lee (Mentor: Gowthami Arepally) of Hematology has received an award (1F32-AI108118-01) from the National Institutes of Health for a project entitled "Biological Significance of Protatmine/Heparin Antibodies." Total funding will be $62,132. Elizabeth A. Reddy of Infectious Diseases has received a sub-award (CHAPNGHHIVS1) through the Clinton Health Access Initiative, Inc. for a project entitled "PNG National Viral Load Program." Total funding will be $40,000. Yutao Liu of Medical Genetics has received an award (1R01EY-023242-01) from the National Institutes of Health for a project entitled "Gene Discovery in Familial Keratoconus." Total funding will be $1,210,221. Brent A. Hanks of Medical Oncology has received an award from the Melanoma Research Alliance for a project entitled "Therapeutic Targeting of the TGF-beta Signaling Axis to Modulate the Tumor Immune Microenvironment and Enhance Melanoma Immunotherapy." Total funding will be $225,000. Melissa E. Hector-Greene (Mentor: Gerard C. Blobe) of Medical Oncology has received an award from the Triangle Community Foundation for a project entitled "2013 Gertrude B. Elion Mentored Medical Student Research Award." Total funding will be $10,000. Michael A. Morse of Medical Oncology has received an award (W81XWH-13-1-0046-BC121792) from the Department of Defense for a project entitled "Use of SMAC Mimetics to Overcome Breast Cancer Resistance to Cancer Immunotherapy." Total funding will be $345,058. Srishti L. Garvey (Mentor: Nicole Calakos) of Neurology has received an award from the Triangle Community Foundation for a project entitled "Fellowship Sponsor." Total funding will be $10,000. David M. Murdoch of Pulmonary, Allergy, and Critical Care Medicine has received an award from the North Carolina Biotechnology Center for a project entitled "Dip Pen Nanolithography." Total funding will be $150,000.[/tab][tab title="Industry-sponsored clinical trials"]John H. Alexander of Cardiology has received an award from Regado Biosciences Inc for a project entitled "Parallel Group Study To Determine the Efficacy and Safety of the REG1 Anticoagulation System aka Regulate PCI." Total funding will be $27,424,146. Richard C. Becker of Cardiology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "DCRI Learn AstraZeneca 2013." Total funding will be $157,667. Christopher Granger of Cardiology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "Regional Systems of Care Demonstration." Total funding will be $400,000. Han W. Kim of Cardiology has received a sub-award (1R44-HL117488-01) through Collagen Medical, LLC for a project entitled "CM-65. A Targeted Contrast Agent for Cardiac Magnetic Resonance Perfusion Imaging." Total funding will be $75,000. Kenneth W. Mahaffey of Cardiology has received an award from GlaxoSmithKline for a project entitled "CEC Melanoma: Indep. Adjudications for All Study Deaths Phase III." Total funding will be $209,986. Rajendra H. Mehta of Cardiology has received an award from Roche Laboratories, Inc. for a project entitled "CEC Adjudications for the Lipid Endpoint Studies." Total funding will be $87,429. Chetan B. Patel of Cardiology has received an award from Amgen, Inc. for a project entitled "COSMIC-HF 20110151." Total funding will be $127,080. Manesh R. Patel of Cardiology has received an award from Volcano Corporation for a project entitled "Volcano Cath Lab Educational Grant." Total funding will be $10,000. Andrew Wang of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Retrospective Analysis of Pulmonary Hypertension Pre- and Post-Mitral Valve Surgery and associated survival." Total funding will be $36,560. Keyur Patel of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "Gilead 342-0102." Total funding will be $83,117. Hayden B. Bosworth of General Internal Medicine has received an award from Improved Patient Outcomes, Inc. for a project entitled "Effect of a patient adherence program on statin adherence in Chinese outpatients." Total funding will be $20,736. Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award from Gamida Cell Ltd for a project entitled "Allogeneic Stem Cell Transplantation of NiCord, Umbilical Cord Blood-derived Ex Vivo Expanded Stem and Progenitor Cells, in Adult Patients with Hematological Malignancies." Total funding will be $280,270. Ara D. Metjian of Hematology has received an award from Baxter Healthcare Corporation for a project entitled "A Phase 2/3, multi-center, open label study of efficacy, safety and pharmacokinetics of PEGylated Recombinant Factor VIII (BAX 855) administered for prophylaxis and treatment of bleeding in previously treated patients with severe Hemophilia A." Total funding will be $46,907. Gary Lyman of Medical Oncology has received an award from Amgen, Inc. for a project entitled "12th Annual Southeastern Fellows Research Skills Retreat." Total funding will be $35,000. Kelly Marcom of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Novartis Breast Cancer Practicum." Total funding will be $66,780. April K. Salama of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A phase III, double-blind, placebo-controlled study of Vemurafenib vs. Vemurafenib plus GDC-0973 in previously untreated BRAF mutation positive patients with unresectable locally advanced or metastatic melanoma." Total funding will be $2,015,529. April K. Salama of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "A phase 3, randomized, double-blind study of Nivolumab monotherapy or Nivolumab combined with Ipilimumab versus Ipilimumab monotherapy in subjects with previously untreated unresctable or metastatic melanoma." Total funding will be $276,651. Hope E. Uronis of Medical Oncology has received an award from Merrimack Pharmaceuticals for a project entitled "Randomized open label phase 2 study of MM-111 and Paclitaxel with or without Trastizumab in patient with traditional and nontraditional HER2 expressing carcinomas of the distal esophagus gastroesophageal (GE) junction and stomach." Total funding will be $304,201. Deborah Boland (Mentor: Mark A. Stacy) of Neurology has received an award from Medtronic, Inc. for a project entitled "Duke Parkinson's Disease and Movement Disorders Fellowship Program." Total funding will be $25,000. Lisa D. Hobson-Webb of Neurology has received an award from Allergan, Inc. for a project entitled "2nd International Conference and Course on Neuromuscular Ultrasound with post Course Guided Chemodenervation Workshop." Total funding will be $10,000. Saurabh Sinha of Neurology has received an award from Cyberonics, Inc. for a project entitled "VNS Therapy Automatic Magnet Mode Outcomes Study in Epilepsy Patients exhibiting Ictal Tachycardia." Total funding will be $125,940. Lake D. Morrison of Pulmonary, Allergy, and Critical Care Medicine has received an award from Gilead Sciences, Inc. for a project entitled "Study to Assess the Efficacy and Safety of GS-6624 in Subjects with Idiopathic Pulmonary Fibrosis." Total funding will be $230,563. Robert T. Keenan of Rheumatology and Immunology has received an award from Savient Pharmaceuticals, Inc. for a project entitled "Savient Education Grant for the Duke School of Medicine Musculoskeletal Ultrasound Training Course." Total funding will be $5,000. Robert T. Keenan of Rheumatology and Immunology has received an award from GE Healthcare for a project entitled "GE Medical Systems Ultrasound & Primary Care Diagnostics, LLC, In-Kind Sponsorship Agreement." Total funding will be $3,348. Robert T. Keenan of Rheumatology and Immunology has received an award from Abbott Laboratories for a project entitled "AbbVie Education Grant for the Duke School of Medicine Musculoskeletal Ultrasound Training Course." Total funding will be $6,000. Robert T. Keenan of Rheumatology and Immunology has received an award from Amgen, Inc. for a project entitled "Amgen Independent Medical Education Agreement 2013 Ultrasound." Total funding will be $10,000.[/tab] [/tabs]

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