New funding awards - May 2016

Sponsored Research

Minjung Choi (Mentor: Robert J. Lefkowitz) of Cardiology has received an award from the American Heart Association for a project entitled "Biophysical Analysis of Я2-Adrenergic Receptor and Я-arrestin1 complex." Total funding will be $51,900.

Adrian F. Hernandez of Cardiology has received a sub-award (16MCPRP27260221) through Massachusetts General Hospital for a project entitled "Mapping the Stroke Transfer Network in the Northeast for Identification of System-level factors Associated with the Quality of Acute Stroke Care Delivery." Total funding will be $20,954.

Eric D. Peterson of Cardiology has received an award from the Society of Thoracic Surgeons for a project entitled "Data Warehousing Center for the Adult Cardiac Surgery, Congenital and Thoracic Databases: 2014 STS Amendments." Total funding will be $226,439.

Geoffrey Pitt of Cardiology has received an award (2T32-HL007101-41) from the National Institutes of Health for a project entitled "Multidisciplinary Heart and Vascular Diseases." Total funding will be $2,886,333.

Reilly W. Coch (Mentor: David D'Alessio) of Endocrinology, Metabolism, and Nutrition has received an award from the Endocrine Fellows Foundation for a project entitled "The Role of Glucagon in Diabetic Ketoacidosis." Total funding will be $7,500.

Matthew D. Hirschey of Endocrinology, Metabolism, and Nutrition has received an award from the Friedreich's Ataxia Research Alliance for a project entitled "Mitochondrial Protein Acetylation and Heart Failure in Friedreich's Ataxia." Total funding will be $100,000.

Santanu K. Datta of General Internal Medicine has received a sub-award through the Portland VA Research Foundation for a project entitled "Lung Cancer Screening Implementation: Evaluation of Patient-Centered Care." Total funding will be $67,853.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award (1R01-CA203950-01) from the National Institutes of Health for a project entitled "Patient-centered home-based hematopoietic stem cell transplantation." Total funding will be $3,159,862.

Luigi Racioppi of Hematological Malignancies and Cellular Therapy has received a sub-award (2U19-AI067773-11) through Columbia University for a project entitled "Determining the mechanism of the protective of action of STO-609, a CaMKK2 inhibitor, in acute radiation syndrome." Total funding will be $53,000.

Marilyn J. Telen of Hematology has received an award (2T32-HL007057-41) from the National Institutes of Health for a project entitled "Transfusion Medicine and Hematology." Total funding will be $2,644,809.

Susanna Naggie of Infectious Diseases has received an award from Brigham and Women's Hospital for a project entitled "ACTG, Aids Clinical Trials Group." Total funding will be $23,424.

Steve Taylor of Infectious Diseases has received an award (1R01-HL134211-01) from the National Institutes of Health for a project entitled "Malaria chemoprevention in children with sickle cell anemia in Western Kenya." Total funding will be $2,867,299.

Jeffrey Crawford of Medical Oncology has received a sub-award (UG1-CA189823) through the Mayo Clinic for a project entitled "Alliance NCI Community Oncology Research Program Agreement (NCORP)."

Loretta Que of Pulmonary, Allergy, and Critical Care Medicine has received an award from the American Lung Association for a project entitled "American Lung Association Airways Clinical Research Centers Network." Total funding will be $100,000.

Craig R. Rackley of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Chest Foundation for a project entitled "PREP - Idiopathic Pulmonary Fibrosis." Total funding will be $36,200.

Industry-sponsored Clinical Trials

Christopher Granger of Cardiology has received an award from Janssen Pharmaceutical, Inc. for a project entitled "Afib Think Tank." Total funding will be $20,000.

David F. Kong of Cardiology has received an award from Terumo BCT, Inc. for a project entitled "SAFE STEMI in Seniors." Total funding will be $749,533.

Martin A. Moseley III of Cardiology has received an award from Kineta, Inc for a project entitled "Proteomics Shared Resource - Kineta SRA 2016." Total funding will be $13,674.

Chetan B. Patel of Cardiology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "Finesse." Total funding will be $3,500.

Manesh R. Patel of Cardiology has received an award from HeartFlow, Inc. for a project entitled "AVANCE Registry." Total funding will be $381,227.

Sudarshan Rajagopal of Cardiology has received an award from Pacesetter, Inc. for a project entitled "CardioMEMS." Total funding will be $196,913.

Hans-Ewald Hohmeier of Endocrinology, Metabolism, and Nutrition has received an award from Johnson & Johnson for a project entitled "A Combinatorial Approach for Stimulating Human Islet Cell Replication." Total funding will be $913,733.

Andrew J. Muir of Gastroenterology has received an award from AbbVie Inc. for a project entitled "Abbvie M13-596: A Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients with Chronic Hepatitis C Virus Genotype 1 - 6 Infection (MAGELLAN-2)." Total funding will be $150,962.

Andrew J. Muir of Gastroenterology has received an award from NGM Biopharmaceuticals, Inc. for a project entitled "A Phase 2, Randomized, Double Blind, Placebo Controlled, Parallel Group, Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of NGM282, Administered for 12 Weeks in Patients with Primary Sclerosing Cholangitis (PSC)." Total funding will be $164,630.

Susanne B. Haga of General Internal Medicine has received an award from Interleukin Genetics, Inc. for a project entitled "Interleukin Engagement Study." Total funding will be $174,999.

Connie Bales of Geriatrics has received an award from the National Pork Board for a project entitled "Does Meal-based Enhancement of Protein Intake Augment Long-term Responses to Sarcopenic Obesity Reduction?" Total funding will be $67,667.

Stefanie Sarantopoulos of Hematological Malignancies and Cellular Therapy has received an award from Gilead Sciences, Inc. for a project entitled "The Effects of Syk Blockade with GS-9973 on Immunity in a Murine Model of GVHD." Total funding will be $174,906.

Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-380-1490." Total funding will be $118,462.

Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-380-1489." Total funding will be $147,318.

Jeffrey Crawford of Medical Oncology has received an award from AstraZeneca LP for a project entitled "REVOLUTION Registry." Total funding will be $26,795,165.

Stephanie Gaillard of Medical Oncology has received an award from Merck for a project entitled "A Pilot Study Investigating the Effect of Pembrolizumab on the Tumoral Immunoprofile of Cancers of Mьllerian Origin." Total funding will be $255,711.

Herbert I. Hurwitz of Medical Oncology has received an award from Incyte Corporation for a project entitled "A platform study exploring the safety tolerability effects on the tumor microenvironment and efficacy of Pembroliumab (MK-3475) + INCB combination." Total funding will be $241,543.

Michael A. Morse of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase III study of pemborlizumab (MK-3475) vs chemotherapy in microstatellite instablility - High (MSI-H) or mismatch repair deficienct (dMMR) stage IV colorectal carcinoma (Keynote - 177)." Total funding will be $153,028.

Michael A. Morse of Medical Oncology has received an award from Aduro BioTech for a project entitled "Long term follow up of subject who participated in aduro sponsored protocols." Total funding will be $87,656.

Andrew B. Nixon of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "Analysis of blood samples from multiple clinical studies evaluating TRC105 in cancer patients." Total funding will be $279,641.

Andrew B. Nixon of Medical Oncology has received an award from NRG Oncology for a project entitled "A Randomized Phase II/III study of the combination of Cediranib and Olaparib compared to Cediranib or Olaparib alone, or Standard of care chemotherapy in women with recurrent platinum-resistant or refractory ovarian, fallopian tube, or primary perito." Total funding will be $358,750.

Andrew B. Nixon of Medical Oncology has received an award from NRG Oncology for a project entitled "Nrg-Gy004, Phase Iii Study Comparing Single-Agent Olaparib Or The Combination Of Cediranib And Olaparib To Standard Platinum-Based Chemotherapy In Women With Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, Or Primary Peritoneal Cancer." Total funding will be $743,750.

Neal E. Ready of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A Randomized, Multicenter, Double- Blind, Phase 3 Study of Nivolumab, Nivolumab in Combination with Ipilimumab, or Placebo as Maintenance Therapy in Subjects with Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC) after Completion of Platinum." Total funding will be $184,559.

Richard F. Riedel of Medical Oncology has received an award from Immune Design Corp. for a project entitled "A Randomized, Open-Label, Phase 2 Trial of CMB305 (Sequentially Administered LV305 and G305) and Atezolizumab in Patients with Locally Advanced, Relapsed, or Metastatic Sarcoma Expressing NY-ESO-1." Total funding will be $146,003.

Hope E. Uronis of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A Multicenter randomized open label study in patients with esophageal cancer refractory or intorlerant to combination therapy with fluoropyrimidine." Total funding will be $153,974.

Tian Zhang of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "A Phase 1 Study To Evaluate The Safety, Pharmacokinetics And Pharmacodynamics Of Escalating Doses Of A Vaccine-Based Immunotherapy Regimen (Vbir) For Prostate Cancer (PF-06753512)." Total funding will be $1,358,767.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Boehringer Ingelheim Corporation for a project entitled "The relationship between the GOLD assessment of COPD and clinical outcomes in a community-based COPD cohort (MURDOCK Observational Study)." Total funding will be $5,262,150.

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