New funding awards - May 2017

Sponsored Research

Adrian F. Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "TO#6: Strategic Planning and Sustainability - Mod 3." Total funding will be $59,379.

Adrian F. Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet Phase II Rapid Research TO#13." Total funding will be $141,939.

Matthew T. Roe of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "ACC-NCDR Partnership with Institutional Research Center." Total funding will be $273,859.

Scott Crown (Mentor: Deborah Muoio) of Endocrinology, Metabolism, and Nutrition has received an award (1F32-HL137398-01) from the National Institutes of Health for a project entitled "13C-Metabolic Flux Analysis for Understanding Cardiac Energy Homeostasis." Total funding will be $160,639.

Matthew D. Hirschey of Endocrinology, Metabolism, and Nutrition has received an award from the Friedreich's Ataxia Research Alliance for a project entitled "Protein Biomarkers in FRDA Cardiomyopathy to Monitor Disease Progression and Therapeutic Efficacy." Total funding will be $100,000.

Andrew J. Muir of Gastroenterology has received an award (2T32-DK007568-26S1) from the National Institutes of Health for a project entitled "Duke Training Grant in Digestive Diseases and Nutrition." Total funding will be $4,549.

Leigh Boulware of General Internal Medicine has received a sub-award (3UL1-TR001064-04S1) through the Tufts University for a project entitled "Tufts CTSA SRC Pilot Study." Total funding will be $36,694.

Harvey Jay Cohen of Geriatrics has received an award (3T32-AG000029-39S1) from the National Institutes of Health for a project entitled "Behavioral and Physiology in Aging (Administrative Supplement)." Total funding will be $10,374.

Kenneth E. Schmader of Geriatrics has received an award (HHSN272201300017I-TO 19-Task D-1) from the National Institutes of Health for a project entitled "VTEU Task Order 13-0045.C1D1.0062 - Task D." Total funding will be $28,717.

Kenneth E. Schmader of Geriatrics has received an award (HHSN272201300017I-TO 19-TaskC-Base) from the National Institutes of Health for a project entitled "VTEU Task Order 13-0045.C1D1.0062 - Task C Option 1." Total funding will be $1,573,519.

Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award through Washington University in St. Louis for a project entitled "A Blinded, Prospective Non-Interventional Observational Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant." Total funding will be $10,125.

Elizabeth S. Dodds Ashley of Infectious Diseases has received a sub-award (1U54-CK000485-01) through the University of Pennsylvania for a project entitled "A Qualitative Study to Identify Meaningful Communication Strategies for Delivering Antimicrobial Stewardship Recommendations and Decisions in U.S. Hospitals." Total funding will be $29,663.

Gregory Gray of Infectious Diseases has received an award from CRDF Global for a project entitled "Duke One Health Training Program, 2017." Total funding will be $101,118.

Brent A. Hanks of Medical Oncology has received an award from the Melanoma Research Alliance for a project entitled "MDSC Recruitment as an Adaptive Resistance Mechanism to PD-1 Ab Resistance." Total funding will be $100,000.

Allison E. Ashley-Koch of Nephrology has received an award from The C&S Patient Education Foundation for a project entitled "Identification of novel MRI parameters and genetic factors for the diagnosis of "classical" Chiari malformation type I." Total funding will be $51,897.

John K. Roberts of Nephrology has received an award from the American Society of Nephrology for a project entitled "Pencast Videos to Boost Learning and Interest in Nephrology Among Internal Medicine Residents." Total funding will be $100,000.

Nathan Rudemiller (Mentor: Steven D. Crowley) of Nephrology has received an award (1F32-HL137253-01) from the National Institutes of Health for a project entitled "The role of dendritic cell-mediated T cell activation in hypertension." Total funding will be $121,632.

Virginia B. Kraus of Rheumatology and Immunology has received an award (1R01-AR071450-01) from the National Institutes of Health for a project entitled "Qualification of Prognostic and Diagnostic Biomarkers of Knee Osteoarthritis." Total funding will be $1,679,353.

Industry-sponsored Clinical Trials

Raymond J. Kim of Cardiology has received an award from Siemens Medical Solutions USA, Inc. for a project entitled "Siemens Educational Program Agreement." Total funding will be $2,450,000.

Jonathan P. Piccini of Cardiology has received an award from Boston Scientific Corporation for a project entitled "Rates of Stroke Among High Risk Medicare Patients with Atrial Fibrillation and Contraindications to Oral Anticoagulation." Total funding will be $105,884.

Sudarshan Rajagopal of Cardiology has received an award from StrideBio LLC for a project entitled "Investigation of the Effect of Expressing BMPr2, BMP10 or BMP9 in the monocrotaline rat model (MCT) and sugen-hypoxia model (SuHX) for PAH following the systemic delivery of genes using an AAV vector." Total funding will be $100,606.

Sudarshan Rajagopal of Cardiology has received an award from Actelion Pharmaceutical US, Inc for a project entitled "A Pilot Study of Transitioning from Parenteral Prostacyclins to Selexipag." Total funding will be $25,141.

Manal F. Abdelmalek of Gastroenterology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "A multi-centre, double-blind, parallel-group, randomised, placebo controlled phase II a study to investigate safety, tolerability, pharmacodynamics, and pharmacokinetics of different doses of orally administered BI 1467335." Total funding will be $265,816.

Manal F. Abdelmalek of Gastroenterology has received an award from Allergan, Inc. for a project entitled "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis." Total funding will be $805,840.

Manal F. Abdelmalek of Gastroenterology has received an award from Allergan, Inc. for a project entitled "Open-label Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis (NASH)." Total funding will be $113,690.

Lindsay King of Gastroenterology has received an award from the Target Corporation for a project entitled "TARGET-PBC A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis." Total funding will be $40,866.

Kimberly L. Blackwell of Medical Oncology has received an award from AstraZeneca AB for a project entitled "TNBC Study." Total funding will be $3,467,397.

Daniel J. George of Medical Oncology has received an award from Janssen Pharmaceutica, Inc. for a project entitled "A Phase II open-label, Multicenter study of Apalutamide, Abiraterone Acetate and Prednisone in African American and Caucasian men with metastatic castrate-resistant prostate cancer." Total funding will be $1,142,459.

Michael A. Morse of Medical Oncology has received an award from Merck for a project entitled "Phase Ib/II Study of Pembrolizumab with Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumors (PLANET)." Total funding will be $819,951.

Tian Zhang of Medical Oncology has received an award from Cantex Pharmaceuticals, Inc. for a project entitled "A Phase 1b, open label, prospective, non-randomized,single center study of conditional lethalithy to copper as a therapeutic modality in prostate cancer." Total funding will be $64,000.

Patricia Lugar of Pulmonary, Allergy, and Critical Care Medicine has received an award from CSL Behring LLC for a project entitled "CSL Behring IgPro20_4004." Total funding will be $80,546.

Omar Mohamedaly of Pulmonary, Allergy, and Critical Care Medicine has received an award from Renovion, Inc. for a project entitled "ARINA-1." Total funding will be $69,492.

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