New Funding Awards May 2025

Congratulations to the following faculty members for receiving these sponsored research awards:

Sponsored Research

Conrad Hodgkinson of Cardiology has received an award (1R01-HL178582-01) from the National Institutes of Health for a project entitled "Novel approaches for cardiac reprogramming: Exosome delivery of reprogramming miRNAs and repressor targeting siRNAs." Total funding will be $1,998,278.

Kevin Thomas of Cardiology has received an award from the Burroughs Wellcome Fund for a project entitled "BOOST Ad Hoc Support for 2025-2026." Total funding will be $9,800.

Thomas Leblanc of Cell Therapy has received a sub-award (1R37-CA288557-01) through the Brigham and Women's Hospital for a project entitled "Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors." Total funding will be $211,485.

Thomas Leblanc of Cell Therapy has received a sub-award (1R01-CA288550-01) through the Massachusetts General Hospital for a project entitled "Multi-Site Randomized Controlled Trial of a Novel Digital Application (DREAMLAND) to Improve Outcomes for Patients with Acute Myeloid Leukemia." Total funding will be $180,806.

Richard Lee of Endocrinology has received a sub-award (OFP-2022C3-30386) through the University of Alabama at Birmingham for a project entitled "RESTORE." Total funding will be $4,500.

Zachary S. Lorsch (Mentor: Diego Bohorquez) of Gastroenterology has received an award (1F32-DK142208-01A1) from the National Institutes of Health for a project entitled "A substrate for durable gut-brain signaling." Total funding will be $111,306.

Susan Hastings of General Internal Medicine has received a sub-award () through the New York University for a project entitled "Growing the Geriatric Emergency care Applied Research (GEAR 1.1) network: Expanding and sustaining an emergency care aging study infrastructure.." Total funding will be $12,099.

Michael Pignone of General Internal Medicine has received a sub-award () through the University of Texas at Austin for a project entitled "Substance Use/Screening Brief Intervention Referral to Treatment (SBIRT) Services." Total funding will be $27,599.

Jonathan Huggins of Infectious Diseases has received a sub-award () through the University of Alabama at Birmingham for a project entitled "Clinical and Applied Research Strategies for the Prevention and Control of Fungal Diseases." Total funding will be $40,504.

Loretta Que of Pulmonary has received a sub-award (979426) through the Icahn School of Medicine at Mount Sinai for a project entitled "Influence of omega-3 status on asthma health during pregnancy." Total funding will be $25,941.



Industry Sponsored Clinical Trials

Melissa Daubert of Cardiology has received an award from Corteria Pharmaceuticals SAS for a project entitled "COR1167-201 study." Total funding will be $486,359.

Adam Devore of Cardiology has received an award from Cytokinetics, Inc. for a project entitled "A MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL TO ASSESS EFFICACY AND SAFETY OF OMECAMTIV MECARBIL IN PATIENTS WITH SYMPTOMATIC HEART FAILURE WITH SEVERELY REDUCED EJECTION FRACTION." Total funding will be $393,615.

Marat Fudim of Cardiology has received an award from scPharmaceuticals for a project entitled "Home-based subcutaneous furosemide for decompensated heart failure." Total funding will be $60,000.

Conrad Hodgkinson of Cardiology has received an award from CRISPR Therapeutics for a project entitled "CTX340 AGT In vivo Gene Editing Collaboration." Total funding will be $20,223.

Michel Khouri of Cardiology has received an award from Eidos Therapeutics for a project entitled "A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial)." Total funding will be $1,404,402.

Zak Loring of Cardiology has received an award from Inova Health Care Services for a project entitled "Score Validation." Total funding will be $1.

Manesh Patel of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "FXI Program." Total funding will be $8,306,949.

Jennifer Rymer of Cardiology has received an award from American College of Cardiology for a project entitled "Cath-PCI Registry." Total funding will be $55,212.

Jennifer Rymer of Cardiology has received an award from St. Jude Medical Business Services Inc. for a project entitled "The Variation in Patient-Reported Outcomes Measures in CLI Patients by Treatment Modality: Insights from the BEST-CLI Registry Patient." Total funding will be $4,995.

Sreekanth Vemulapalli of Cardiology has received an award from American College of Cardiology for a project entitled "TVT Registry 2025." Total funding will be $1,121,394.

Danielle Brander of Cell Therapy has received an award from Carna Biosciences, Inc. for a project entitled "A Phase 1b Study of Oral AS-1763 in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma." Total funding will be $393,294.

Sanghee Hong of Cell Therapy has received an award from Gamida Cell Inc. for a project entitled "Abatacept for Omidubicel Transplant." Total funding will be $297,623.

Yubin Kang of Cell Therapy has received an award from Karyopharm Therapeutics for a project entitled "A phase II safety and efficacy study of Selinexor in combination with bispecific antibody in patients with relapsed/refractory multiple myeloma." Total funding will be $605,255.

David Leiman of Gastroenterology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "Dupixent Registry R668-EE-2328 EDESIA Pro00117064." Total funding will be $43,094.

William Yancy of General Internal Medicine has received an award from Cleerly, Inc for a project entitled "TRANSFORM." Total funding will be $1,643,404.

Andrew Armstrong of Oncology has received an award from Amgen, Inc. for a project entitled "Amgen AMG509 mCRPC - A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Subjects With Metastatic Castration-Resistant Prostate Cancer Previously Treated With Chemotherapy." Total funding will be $1,704,258.

Jeffrey Clarke of Oncology has received an award from Amgen, Inc. for a project entitled "A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects with Small Cell Lung Cancer (SCLC)(DeLLphi-309)." Total funding will be $3,037,329.

Jeffrey Clarke of Oncology has received an award from Lilly USA, LLC for a project entitled "SUNRAY-01, A Global Pivotal Study in Participants with KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First-Line Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in those with PD-L1 express." Total funding will be $245,526.

Daniel George of Oncology has received an award from Convergent Therapeutics, Inc. for a project entitled "A Phase 2, Open-label Study Evaluating Dosimetry, Randomized Dose Optimization, Dose Escalation and Efficacy of Ac-225 Rosopatamab Tetraxetan in Participants with PSMA PET-Positive Castration-Resistant Prostate Cancer." Total funding will be $310,067.

Michael Harrison of Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase 1b/2 Study of Immune and Targeted Combination Therapies in Participants with RCC (KEYMAKER-U03): Substudy 03C in Participants With Recurrent Disease During or After Anti-PD-(L)1 Adjuvant Therapy." Total funding will be $722,834.

Christopher Hoimes of Oncology has received an award from Amgen, Inc. for a project entitled "A Phase 1 First-in-Human Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 355 as Monotherapy and in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors." Total funding will be $1,439,084.

Niharika Mettu of Oncology has received an award from Pheast Therapeutics, Inc. for a project entitled "An open-label, Phase 1a/1b, dose escalation and dose expansion study investigating the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of PHST001 in adult patients with advanced relapsed and/or refractory solid tumors." Total funding will be $332,720.

Niharika Mettu of Oncology has received an award from Boundless Bio, Inc. for a project entitled "An Open-Label, Multicenter, First-in-Human, Dose-Escalation and Dose-Expansion, Phase 1/2 Study of BBI-355 and BBI-355 in Combination with Select Targeted Therapies in Subjects with Locally Advanced or Metastatic Solid Tumors with Oncogene Amplificat." Total funding will be $272,360.

Cameron Oswalt of Oncology has received an award from AstraZeneca AB for a project entitled "A Phase III, Randomised, Open-label, Global Study of Adjuvant Datopotamab Deruxtecan (Dato-DXd) in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants Wi." Total funding will be $1,463,111.

Richard Riedel of Oncology has received an award from Kura Oncology, Inc. for a project entitled "A Phase 1a/1b Study of the Safety, Pharmacokinetics, and Antitumor Activity of the Oral Menin Inhibitor Ziftomenib in Combination with Imatinib in Patients with Advanced Gastrointestinal Stromal Tumors (GIST) After Imatinib Failure." Total funding will be $466,524.

April Salama of Oncology has received an award from Linnaeus Therapeutics, Inc. for a project entitled "A Multicenter, Open-Label, Randomized, Controlled Study to Assess the Antitumor Activity of LNS8801 With and Without Pembrolizumab in Patients With Treatment-Refractory, Unresectable Melanoma." Total funding will be $1,330,226.

John Strickler of Oncology has received an award from Quanta Therapeutics, Inc. for a project entitled "QTX3544-201 A Phase 1 Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of QTX3544 in Patients with Advanced Solid Tumors with KRASG12V Mutations." Total funding will be $1,214,047.

John Strickler of Oncology has received an award from Accent Therapeutics, Inc. for a project entitled "A Phase 1/2 Study of ATX-559, an Oral Inhibitor of the Helicase DHX9 in Patients with Locally Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers." Total funding will be $3,000.

Patricia Lugar of Pulmonary has received an award from Shanghai Argo Biopharmaceutical Co., Ltd for a project entitled "Argo BW-20805-2001." Total funding will be $342,721.

Kamran Mahmood of Pulmonary has received an award from Galvanize Therapeutic Inc. for a project entitled "Galvanize PROPEL Registry study - An observational, retrospective and prospective, single-arm, consecutive enrollment, multi-center registry. This registry will be conducted at up to 25 sites in the US.." Total funding will be $47,700.

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