New funding awards - November 2020

Sponsored Research

Elizabeth H. Weissler (Mentor: William Jones) of Cardiology has received an award (1F32-HL151181-01A1) from the National Institutes of Health for a project entitled "Addressing variability in peripheral arterial disease outcomes using machine learning techniques." Total funding will be $166,812.

William Jones of Cardiology has received a sub-award (20115 12597 221010 F) through the University of North Carolina - Asheville for a project entitled "CDRN Data Extraction for UNCA-UNC Covid project." Total funding will be $10,462.

William Jones of Cardiology has received a sub-award () through the East Carolina University for a project entitled "Subaward ECU/Mishriky Trial Data Extraction." Total funding will be $6,757.

Robert Mentz of Cardiology has received a sub-award (1R01-HL154768-01) through the Inova Health System for a project entitled "Targeted discovery longitudinal proteomics to understand the systems biology difference of furosemide vs. torsemide for patients with heart failure: An ancillary study of TRANSFORM-HF." Total funding will be $45,737.

Kristin Newby of Cardiology has received an award from the University of North Carolina - Chapel Hill for a project entitled "NC Wastewater Surveillance & MURDOCK COVID-19 Study." Total funding will be $7,962.

Ann Brown of Endocrinology has received an award from the Doris Duke Charitable Foundation for a project entitled "Fund to Retain Clinical Scientists at Duke." Total funding will be $528,000.

Jatin Roper of Gastroenterology has received a sub-award (1R01-CA244359-01A1) through the Texas A&M University for a project entitled "Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signaling." Total funding will be $100,223.

Leigh Boulware of General Internal Medicine has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Putting Patients at the Center of Kidney Care Transitions." Total funding will be $64,409.

Harvey Jay Cohen of Geriatrics has received a sub-award (1R01-AG068193-01) through the Georgetown University for a project entitled "Alzheimer's Disease and Cancer-related Cognitive Decline." Total funding will be $18,127.

Grace Lee of Hematology has received an award (1R21-AI156143-01) from the National Institutes of Health for a project entitled "Neutrophil Activation Phenotypes in Healthy Subjects and Implications for Bacterial Clearance." Total funding will be $442,750.

Deverick Anderson of Infectious Diseases has received an award (200-2016-91776I Domain 1-TO3) from the Centers for Disease Control and Prevention for a project entitled "Evaluating SARS-CoV2 vaccine effectiveness among health care personnel during early phase vaccination." Total funding will be $467,417.

Megan Reller of Infectious Diseases has received an award from the Yale University for a project entitled "Ph II randomized double blind placebo-controlled, study of LAM-002A for the preventation of progression of COVID-19." Total funding will be $254,095.

Chris Woods of Infectious Diseases has received an award from the Sergey Brin Family Foundation for a project entitled "Predictors of Severe COVID-19 Outcomes (PRESCO)." Total funding will be $800,000.

Christopher Hoimes of Medical Oncology has received a sub-award (1-R01CA253627-01) through the Case Western Reserve University for a project entitled "Targeted immuno-nanoparticles for directing antitumor immune response against breast cancer metastasis." Total funding will be $7,306.

Andrew Nixon of Medical Oncology has received an award from the NRG Oncology for a project entitled "Identification and validation of plasma-based protein biomarkers for cediranib and olaparib in GY005, phase III." Total funding will be $1.

Kevin Oeffinger of Medical Oncology has received a sub-award (1R01-CA249460-01) through the City of Hope for a project entitled "Technology-Enabled Activation of Skin Cancer Screening for Hematopoietic Cell Transplantation Survivors and their Primary Care Providers." Total funding will be $19,006.

Industry-sponsored Clinical Trials

Adrian Hernandez of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "CV Precision Medicine Research Alliance - Governance." Total funding will be $490,628.

Conrad Hodgkinson of Cardiology has received an award from Recardia Therapeutics, Inc. for a project entitled "Recardia Therapeutics SRA." Total funding will be $18,761.

Robert Mentz of Cardiology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "Exscel Biomarker Analysis and Secondary Manuscript Production." Total funding will be $418,621.

Thomas Povsic of Cardiology has received an award from XyloCor Therapeutics for a project entitled "Direct Administration of AdVEGF-All6A+ LOI." Total funding will be $37,289.

Andrew Wang of Cardiology has received an award from MyoKardia, Inc. for a project entitled "VALOR-HCM." Total funding will be $388,165.

Manal Abdelmalek of Gastroenterology has received an award from NGM Biopharmaceuticals, Inc. for a project entitled "Evaluation of Efficacy, Safety and Tolerability of NGM282 (Aldafermin) in Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (ALPINE 4)." Total funding will be $112,550.

Danielle Brander of Hematologic Malignancies and Cellular Therapy has received an award from Loxo Oncology, Inc. for a project entitled "LOXO Oncology study." Total funding will be $274,555.

Nicholas Turner of Infectious Diseases has received an award from PDI, Inc. for a project entitled "Measuring the Impact of Enhanced Strategies for Daily Disinfection in Acute Care Hospital Rooms: Sani24 vs. Routine Daily Disinfection." Total funding will be $30,832.

Carey Anders of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "A TWO-PART, PHASE 1A/B, OPEN-LABEL, MULTICENTER TRIAL EVALUATING PHARMACOKINETICS, SAFETY AND EFFICACY OF PF-07284890 (ARRY-461) IN PARTICIPANTS WITH BRAF V600-MUTANT SOLID TUMORS WITH AND WITHOUT BRAIN INVOLVEMENT." Total funding will be $277,722.

Jeffrey Crawford of Medical Oncology has received an award from AstraZeneca AB for a project entitled "A Phase III, Randomized, Multicenter, Double-blind, Placebo-controlled Study to Determine the Efficacy of Adjuvant Durvalumab in Combination with Platinum-based Chemotherapy in Completely Resected Stage II-III NSCLC (MeRmaiD-1)." Total funding will be $174,784.

Daniel George of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "Odyssey RCC." Total funding will be $2,500,000.

Brent Hanks of Medical Oncology has received an award from 4SC for a project entitled "MERKLIN-2." Total funding will be $765,043.

Brent Hanks of Medical Oncology has received an award from Exicure, Inc for a project entitled "Exicure AST-008-102." Total funding will be $272,504.

Niharika Mettu of Medical Oncology has received an award from Repare Therapeutics for a project entitled "Repare RP-3500-01." Total funding will be $233,904.

Niharika Mettu of Medical Oncology has received an award from BioMed Valley Discoveries for a project entitled "A Two-Part, Phase II, Multi-center Study of the ERK Inhibitor Ulixertinib (BVD-523) for Patients with Advanced Malignancies Harboring MEK or Atypical BRAF Alterations." Total funding will be $141,877.

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