New funding awards - October 2017

Sponsored Research

Adrian F. Hernandez of Cardiology has received an award (1U24-AT009676-01) from the National Institutes of Health for a project entitled "NIH Health Care Systems Research Collaboratory - Coordinating Center." Total funding will be $9,249,243.

Eric D. Peterson of Cardiology has received an award (1R01-HL134679-01) from the National Institutes of Health for a project entitled "The Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction (SPIRRIT-HFPEF)." Total funding will be $8,097,219.

Luigi Racioppi of Hematological Malignancies and Cellular Therapy has received a sub-award (1R01-CA218442-01) through the University of North Carolina - Chapel Hill for a project entitled "Identify chemical probes for CAMKK2 to target the tumor microenvironment and enhance anti-tumor immune response." Total funding will be $98,978.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received a sub-award (5R01-HL129472-03) through the Memorial Sloan-Kettering Cancer Center for a project entitled "Selection of Allogeneic Hematopoietic Cell Donor Based on KIR and HLA Genotypes." Total funding will be $8,506.

Gowthami Arepally of Hematology has received a sub-award (5U19-FD004994-05) through the University of North Carolina - Chapel Hill for a project entitled "Probing the heparin structural elements for high risk of heparin-induced thrombocytopenia (HIT)." Total funding will be $50,000.

Oluwatoyosi Onwuemene of Hematology has received a sub-award through the Hemophilia & Thrombosis Research Society for a project entitled "Defining the role of therapeutic plasma exchange in heparin induced thrombocytopenia." Total funding will be $81,000.

Marilyn J. Telen of Hematology has received an award from the Doris Duke Charitable Foundation for a project entitled "Genetic Pathways Affecting High Throughput Adhesion Assays." Total funding will be $54,000.

Ewa M. Wysokinska of Hematology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Comparison of Oral anticoagulants for extended VEnous Thromboembolism (COVET)."

Julia Xu (Mentor: Marilyn J. Telen) of Hematology has received an award from Cooley's Anemia Foundation for a project entitled "Thalassemia Screening in Myanmese and Lao Migrants in Thailand." Total funding will be $32,500.

Nathan M. Thielman of Infectious Diseases has received a sub-award (2D43-TW009337-07) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $24,456.

Megan E. Reller of Infectious Diseases has received an award (7R03-AI111300-03) from the National Institutes of Health for a project entitled "Rickettsial Infections In Malaysia." Total funding will be $67,565.

Nathan M. Thielman of Infectious Diseases has received a sub-award (2D43-TW009337-07) through the Vanderbilt University Medical Center for a project entitled "Fogarty Global Health Training Program." Total funding will be $14,083.

Kimberly L. Blackwell of Medical Oncology has received an award from Johns Hopkins University for a project entitled "TBCRC Aurora Us: Retrospective Tissue Collection." Total funding will be $19,000.

Andrew B. Nixon of Medical Oncology has received an award from the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Blood-based Biomarker Profiling for Lenvatinib in Advanced Rectal Adenocarcinoma." Total funding will be $50,464.

Allison E. Ashley-Koch of Nephrology has received an award through the University of Connecticut for a project entitled "Genome-wide Association Analysis in the Neurocognitive Outcomes of Depression in the Elderly (NCODE) data set." Total funding will be $81,083.

Industry-sponsored Clinical Trials

John H. Alexander of Cardiology has received an award from CSL Behring LLC for a project entitled "CSL112_STEMI." Total funding will be $105,052,336.

Renato D. Lopes of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "An Open-Label Study To Evaluate The Long-Term Safety And Efficacy Of Evinacumab In Patients With Homozygous Familial Hypercholesterolemia." Total funding will be $217,949.

Renato D. Lopes of Cardiology has received an award from Amgen, Inc. for a project entitled "AMG785-2015242." Total funding will be $246,730.

Renato D. Lopes of Cardiology has received an award from Sanofi US for a project entitled "Sanofi SOTA Outcomes 14875." Total funding will be $8,807,774.

Manal F. Abdelmalek of Gastroenterology has received an award from TARGET PharmaSolutions, Inc. for a project entitled "A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepatitis." Total funding will be $38,084.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award from DxTerity Diagnostics for a project entitled "Biodosimetry High-Throughput Test RFP-16-100-SOL-00010." Total funding will be $700,160.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Janssen Research & Development, LLC for a project entitled "Phase 2, Randomized, Open-Label Study comparing Daratumumab, Lenalidomide, Bortezomib, and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects with Newly Diagnosed Multiple Myeloma Eligible for High dose chemo." Total funding will be $350,969.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Tolero Pharmaceuticals, Inc for a project entitled "A Phase 2, Randomized, Biomarker-driven, Clinical Study in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML) with an Exploratory Arm in Patients with Newly Diagnosed High-Risk AML." Total funding will be $210,526.

Murat O. Arcasoy of Hematology has received an award from CTI Biopharma Corp. for a project entitled "An Open-Label, Randomized, Phase 2 Dose-Finding Study of Pacritinib in Patient with Thrombocytopenia and Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis Previously Treated with Essential." Total funding will be $117,518.

Ivy Altomare of Medical Oncology has received an award from Incyte Corporation for a project entitled "Prospective, Longitudinal, Non-Interventional Study Of Disease Burden And Treatment Of Patients With Low-Risk Myelofibrosis (Mf) Or High-Risk Essential Thrombocythemia (Et) Or Et Patients Receiving Et-Directed Therapy." Total funding will be $46,358.

Jeffrey Crawford of Medical Oncology has received an award from EMD Serono Inc for a project entitled "EMD Serono, Inc. Education Event." Total funding will be $74,736.

Daniel J. George of Medical Oncology has received an award from Janssen Pharmaceutica, Inc. for a project entitled "A Phase 2 Efficacy and Safety Study of Niraparib in Men with Metastatic Castration-resistant Prostate Cancer and DNA-Repair Anomalies." Total funding will be $241,607.

Michael R. Harrison of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "Phase 3b/4 Safety Trial of Nivolumab Combined with Ipilimumab in Subjects." Total funding will be $113,449.

Niharika B. Mettu of Medical Oncology has received an award from OncoMed Pharmaceuticals for a project entitled "A Phase 1a Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of OMP-313M32 Administered as a Single Agent to Subjects with Locally Advanced or Metastatic Solid Tumors." Total funding will be $315,144.

Andrew B. Nixon of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "Analysis of baseline blood samples from a clinical study evaluating TRC105 in metastatic renal cell carcinoma cancer patients." Total funding will be $133,726.

Richard F. Riedel of Medical Oncology has received an award from NanoCarrier Co., Ltd. for a project entitled "A Phase 1b/2 Dose-Escalation and Expansion Trial of NC-6300 (Nanoparticle Epirubicin) in Patients with Advanced Solid Tumors or Advanced, Metastatic, or Unresectable Soft Tissue Sarcoma." Total funding will be $297,157.

Thomas Stinchcombe of Medical Oncology has received an award from Blueprint Medicines Corporation for a project entitled "A Phase 1 Study of the Highly-selective RET Inhibitor, BLU-667, in Patients with Thyroid Cancer, Non-Small Cell Lung Cancer (NSCLC) and Other Advanced Solid Tumors." Total funding will be $209,322.

John H. Strickler of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "A Phase 1, multicenter, open-label, dose-escalation study of SNF-2FF in patients with advanced solid tumors." Total funding will be $402,097.

Tian Zhang of Medical Oncology has received an award from AbbVie Inc. for a project entitled "An Open-Label Study of Rovalpituzumab Tesirine in Subjects with Delta-Like Protein 3-Expressing Advanced Solid Tumors." Total funding will be $1,077,812.

Tian Zhang of Medical Oncology has received an award from Merrimack Pharmaceuticals for a project entitled "MM-310-01-01-01: A Phase 1 Study Evaluating the Safety, Pharmacology and Preliminary Activity of MM-310 in Patients with Solid Tumors." Total funding will be $428,416.

Robert T. Keenan of Rheumatology and Immunology has received an award from SOBI for a project entitled "Sobi ANAKIN-401." Total funding will be $150,726.

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