Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
[tabs style="vertical"][tab title="Sponsored research"]Robert M. Califf of Cardiology has received an award (3U54-AT007748-02S2) from the National Institutes of Health for a project entitled "Health Care Systems Research Collaboratory -Empirical Ethics Supplement." Total funding will be $1,999,999.
Geoffrey S. Ginsburg of Cardiology has received an award (3U01-HG007282-01S1) from the National Institutes of Health for a project entitled "Implementation, Adoption, and Utility of Family History in Diverse Care Settings." Total funding will be $130,000.
Paul B. Rosenberg of Cardiology has received an award (3R01-HL093470-05S1) from the National Institutes of Health for a project entitled "The role of STIM1 in cardiac and skeletal muscle function." Total funding will be $157,000.
Galen S. Wagner of Cardiology has received an award from the Oak Ridge Institute for Science and Education for a project entitled "Research Participation Program ORISE/FDA." Total funding will be $19,464.
Wei Chen of Gastroenterology has received an award (BC123280P1) from the Department of Defense for a project entitled "Targeting the WNT/beta-catenin pathway in triple negative breast cancer." Total funding will be $294,375.
Deborah A. Fisher of Gastroenterology has received an award (1R21-DK095790-01-A1) from the National Institutes of Health for a project entitled "Understanding recommendations for screening colonoscopy intervals." Total funding will be $431,750.
Katherine Garman of Gastroenterology has received a sub-award (5P30-DK034987-28 REV) through the University of North Carolina - Chapel Hill for a project entitled "Development of a Porcine Model of Esophageal Injury and Repair." Total funding will be $30,000.
Nancy M. McGreal of Gastroenterology has received a sub-award (1U01-DK092239-02) through the University of North Carolina - Chapel Hill for a project entitled "Randomized, double blind, prospective trial investigating the efficacy of Methotrexate in induction and maintenance of steroid free remission in ulcerative colitis (MEthotrexate Response In Treatment of UC - MERIT-UC)." Total funding will be $14,117.
Stewart C. Alexander of General Internal Medicine has received a sub-award (RSG-13-239-01-PCSM) through the University of Rochester for a project entitled "Prognosis Communication and Race in Advanced Cancer Care." Total funding will be $8,454.
Soko Setoguchi-Iwata of General Internal Medicine has received an award (1R21-AG044294-01A) from the National Institutes of Health for a project entitled "Heat Waves, Medication Use, and Adverse Health Outcomes Among Older Adults." Total funding will be $431,750.
Danielle M. Brander of Hematological Malignancies and Cellular Therapy has received an award (W81XWH-13-1-0358 CA120064) from the Department of Defense for a project entitled "Understanding Drug Resistance to Targeted Therapeutics in Malignant B-Cell Lymphoproliferative Disorders (CA120064)." Total funding will be $308,400.
Murat O. Arcasoy of Hematology has received an award through the Mount Sinai School of Medicine for a project entitled "Pegylated Interferon Alfa-2a vs Hydroxyurea Therapy." Total funding will be $19,200.
Marilyn J. Telen of Hematology has received an award from the Doris Duke Charitable Foundation for a project entitled "Extension of Hematologic & Clinical Genotype-Phenotype Associations in SCD Using Exome Chip & Metabolomic Analysis." Total funding will be $54,000.
Deverick J. Anderson of Infectious Diseases has received a sub-award (3U54-CK000172-03S1) through Harvard University for a project entitled "Wake-up and Breathe sVAP Collaborative." Total funding will be $64,825.
John A. Bartlett of Infectious Diseases has received a sub-award (ryan white funds) through the Wake County Human Services for a project entitled "HIV Adult ID Services through Wake County, Year 5." Total funding will be $143,998.
Gary M. Cox of Infectious Diseases has received a sub-award (5U19-AI096113-03) through the University of North Carolina - Chapel Hill for a project entitled "UNC Margolis Training Agreement - Sung." Total funding will be $11,747.
Amy P. Abernethy of Medical Oncology has received an award through the University of South Florida for a project entitled "Patient Reported Outcomes in Breast Cancer Surgery." Total funding will be $32,750.
Amy P. Abernethy of Medical Oncology has received a sub-award (IRG-86-004-26) through the Medical College of Wisconsin for a project entitled "ACS Pilot QOL Study: ePRO Data for Patients Receiving Chemotherapy for GI Cancer." Total funding will be $20,000.
Amy P. Abernethy of Medical Oncology has received an award (1R18-HS022763-01) from the Agency for Healthcare Research and Quality for a project entitled "Implementing best practice in palliative care." Total funding will be $2,492,207.
Michael A. Morse of Medical Oncology has received an award (BC123280) from the Department of Defense for a project entitled "Targeting the WNT/beta-catenin Pathway in Triple Negative Breast Cancer." Total funding will be $295,021.
Laura P. Svetkey of Nephrology has received an award (3U01-HL096720-05S1) from the National Institutes of Health for a project entitled "Cell Phone Intervention for Young Adults - Diversity Supplement." Total funding will be $63,214.
Michael Merson of Other Medicine has received a sub-award through the University of Indiana for a project entitled "Indiana University/Duke University Eldoret Kenya Project." Total funding will be $50,010.[/tab][tab title="Industry-sponsored clinical trials"]
John H. Alexander of Cardiology has received an award from Bristol-Myers Squibb for a project entitled "LOI: Apixaban AF/ACS Study." Total funding will be $127,238.
Pamela S. Douglas of Cardiology has received an award from Abiomed for a project entitled "IMPELLA RECOVER RIGHT Clinical Trial." Total funding will be $258,173.
William E. Kraus of Cardiology has received an award from Valencell, INC for a project entitled "Multiwavelength Optical Emitter for Biomedical Diagnostics." Total funding will be $15,429.
Manesh R. Patel of Cardiology has received an award from Medtronic, Inc. for a project entitled "Renal Denervation in Patients with Uncontrolled Hypertension -SYMPLICITY HTN-4." Total funding will be $667,279.
Katherine Garman of Gastroenterology has received an award through SAIC-Frederick, Inc. for a project entitled "Duke Upper GI Cancer Repository for the Cancer Genome Atlas." Total funding will be $53,775.
Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "A Phase 2, Multicenter, Open-Label Study to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir." Total funding will be $304,487.
Andrew J. Muir of Gastroenterology has received an award from Pharmaceutical Specialties, Inc. for a project entitled "Pharmaceutical Specialties Commercial Support CME." Total funding will be $1,500.
Jane E. Onken of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-326-0101." Total funding will be $377,672.
David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Epizyme, Inc for a project entitled "Phase I involving EPZ-5676 in Leukemia Patients with MLL gene or Advanced Hematologic Malignancies." Total funding will be $338,480.
Ara D. Metjian of Hematology has received an award from GlaxoSmithKline for a project entitled "A randomized, blinded, placebo-controlled, dose finding study to assess the safety and efficacy of the oral thrombopoietin receptor agonist, eltrombopag, administered to subjects with acute myelogenous leukaemia (AML) receiving induction chemotherapy." Total funding will be $78,528.
Nirmish R. Shah of Hematology has received an award from Bristol-Myers Squibb for a project entitled "Impact of Daily Prophylaxis Dose Anticoagulation with a Factor Xa Inhibitor (Apixaban) in Patients with Sickle Cell Disease." Total funding will be $193,071.
Susanna Naggie of Infectious Diseases has received an award from Bristol-Myers Squibb for a project entitled "BMS-AI-452032." Total funding will be $805,358.
Michael A. Morse of Medical Oncology has received an award from Advanced Accelerator Applications SA for a project entitled "A multicentre, stratified open randomized comparator-contrlled parallel group phase III study comparing treatment with Lu-DOTA-Tyr3-Octreotate to Octreotide LAR in patients with inoperable, progressive, somatostatin receptor positive midgut." Total funding will be $421,941.
Michael A. Morse of Medical Oncology has received an award from AlphaVax, Inc. for a project entitled "A pilot study of active immunotherapy with CEA (6D) VRP vaccine (AVX701) in patients with stage III colon cancer." Total funding will be $212,843.
Michael A. Morse of Medical Oncology has received an award from Precision Biologic for a project entitled "A Multicenter Phase I/IIB study of NPC-1C in combination with gemcitabine in patients with metastatic or locally advanced pancreatic cancer previously treated with FOLFIRINOX." Total funding will be $97,158.
Fatima A. Rangwala of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "A Phase I open-label Multicenter 3-period fixed sequence study to investigate in the effect of Vemurafenib on the pharmacokinetics of a singke dos ot Tizanidine (A cyp1a2 substrate) in patients with BRAF v600 mutation-positive metastatic malignancy." Total funding will be $124,201.
Fatima A. Rangwala of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "A Phase IV postmarketing open label extension (Rollover) study of Vemurafinib in patients with BRAF v600 mutation positive malignancies previously enrolled in an antecedent Vemurafinib protocol." Total funding will be $197,673.
April K. Salama of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "Phase 2, Single-arm study of Nivolumab (BMS-936558) in combination with Ipilimumab in subjects with previously untreated." Total funding will be $140,672.[/tab]
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