Telen
Principal Investigator
Wellcome Clinical Distinguished Professor of Medicine in Honor of R. Wayne Rundles, M.D.
Professor of Medicine
Associate Professor of Pathology
Member of the Duke Cancer Institute
Contact Information

Campus mail
DUMC Box 2615

Physical address
Rm 337 MSRB1
Duke University Medical Center
Durham, NC 27710

Phone
Office: 919-684-5999

Email
marilyn.telen@duke.edu

Overview

Lab Members

Marilyn Telen, MD
‚Äč
Wellcome Professor of Medicine, Division of Hematology
Associate Medical Director, Duke Hospital Transfusion Service
Director, Duke Comprehensive Sickle Cell Center

Martha Delahunty, PhD
Research Scientist

Milena Batchvarova, M.S.

Current Studies

The Erythrocye and SCD Biology Lab focuses on the behavior and interactions of red cells and other blood cells in sickle cell disease, including especially the role of adhesion molecules on red cells and how their activity is regulated by the erythrocyte. The lab also explore the mechanisms whereby non-hemoglobin gene polymorphisms affect pathophysiology and clinical outcomes in sickle cell disease.

An additional interest of the laboratory is the physiologic and pathophysiologic roles of proteins that bear erythrocyte blood group antigens, and how genetic variants do or do not affect these functions.

Blood diagram
RBC-Endothelial interactions
Sevuparin reduces in vivo SS RBC adhesion