Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

Researchers in the Duke Division of Pulmonary, Allergy, and Critical Care Medicine are actively engaged in clinical trials that examine effective treatment options for chronic obstructive pulmonary disease (COPD).

Current Clinical Trials

Select a trial to read more details on the Web site:


Historically Relevant Clinical Trials

Select a trial to read the full description on the Web site.

Effectiveness of Long-term Oxygen Therapy in Treating People With Chronic Obstructive Pulmonary Disease (The Long-term Oxygen Treatment Trial [LOTT])
This study will evaluate the effectiveness of supplemental oxygen therapy in treating people with COPD who have moderately low blood oxygen levels at rest or who have normal blood oxygen levels at rest, but have low or very low blood oxygen levels during exercise.

Principal Investigator: Neil MacIntyre, MD

Examining the Genetic Factors That May Cause Chronic Obstructive Pulmonary Disease (COPD) (COPDGene)
Chronic obstructive pulmonary disease (COPD) is a long-term lung disease that is often caused by cigarette smoking. The purpose of this study is to evaluate whether certain genetic factors predispose some smokers to develop COPD more than others.

Principal Investigator: Neil MacIntyre, MD

Validation of PROMIS Banks With COPD Exacerbations
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and demographic characteristics. 

Principal Investigator: Neil MacIntyre, MD

Enroll in a Pulmonary Clinical Trial at Duke

Researchers in our division are investigating a variety of treatments and therapies to respond to lung disease. Click here for a list of current clinical trials.