Andrew Joseph Muir, MD

Professor of Medicine
Chief, Division of Gastroenterology in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 03137B Hosp South, Durham, NC 27710
Phone (919) 684-2052
Email address
  • Hepatitis C 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver disease 
  • Outcomes Research
In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 1998 - 2000
  • Chief Medical Resident, Medicine, Duke University, 1997 - 1998
  • Fellow in Gastroenterology, Medicine, Duke University, 1996 - 1997
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., Duke University, 1993


Wilder, J, Saraswathula, A, Hasselblad, V, and Muir, A. "A Systematic Review of Race and Ethnicity in Hepatitis C Clinical Trial Enrollment." Journal of the National Medical Association 108, no. 1 (February 2016): 24-29.

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Sulkowski, MS, Vargas, HE, Di Bisceglie, AM, Kuo, A, Reddy, KR, Lim, JK, Morelli, G, Darling, JM, Feld, JJ, Brown, RS, Frazier, LM, Stewart, TG, Fried, MW, Nelson, DR, Jacobson, IM, and HCV-TARGET Study Group, . "Effectiveness of Simeprevir Plus Sofosbuvir, With or Without Ribavirin, in Real-World Patients With HCV Genotype 1 Infection." Gastroenterology 150, no. 2 (February 2016): 419-429.

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Oloruntoba, O, and Muir, AJ. "Integrating daclatasvir into hepatitis c therapy." Clinical Liver Disease 7, no. 1 (January 2016): 1-4.

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Curry, MP, O'Leary, JG, Bzowej, N, Muir, AJ, Korenblat, KM, Fenkel, JM, Reddy, KR, Lawitz, E, Flamm, SL, Schiano, T, Teperman, L, Fontana, R, Schiff, E, Fried, M, Doehle, B, An, D, McNally, J, Osinusi, A, Brainard, DM, McHutchison, JG, Brown, RS, Charlton, M, and ASTRAL-4 Investigators, . "Sofosbuvir and Velpatasvir for HCV in Patients with Decompensated Cirrhosis." The New England journal of medicine 373, no. 27 (December 2015): 2618-2628.

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Charlton, MR, O'Leary, JG, Bzowej, NH, Muir, AJ, Korenblat, KM, Fenkel, JM, Reddy, KR, Lawitz, E, Schiano, TD, Teperman, LW, Fontana, RJ, Schiff, ER, Fried, MW, Doehle, B, An, D, McNally, J, Osinusi, A, Brainard, DM, McHutchison, JG, Brown, RS, and Curry, MP. "Sofosbuvir/Velpatasvir Fixed Dose Combination For The Treatment Of HCV In Patients With Decompensated liver Disease: The Phase 3 ASTRAL-4 Study." December 2015.


Muir, AJ, and Naggie, S. "Hepatitis C Virus Treatment: Is It Possible To Cure All Hepatitis C Virus Patients?." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 13, no. 12 (November 2015): 2166-2172. (Review)

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Wilder, JM, and Muir, AJ. "Strategies for treating chronic HCV infection in patients with cirrhosis: latest evidence and clinical outcomes." Therapeutic advances in chronic disease 6, no. 6 (November 2015): 314-327. (Review)

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French, D, Goodman, ZD, Huntzicker, EG, Newstrom, D, Karnik, S, Smith, V, Schall, REA, Kanwar, B, Subramanian, M, McHutchison, JG, Muir, AJ, and Myers, RP. "Expression of matrix metalloproteinase 9 (MMP9) and the apoptosis signal-regulating kinase 1 (ASK1) pathway activation marker, phospho-P38 (p-P38), in primary sclerosing cholangitis (PSC)." October 2015.


Muir, AJ, Charlton, MR, Pang, PS, Stamm, LM, Brainard, DM, McHutchison, JG, Afdhal, NH, and Watkins, PB. "Detecting Drug-Induced Liver Injury in Patients with Decompensated Chronic Hepatitis C: A Review of the SOLAR-1 and SOLAR-2 Studies." October 2015.


Reau, N, Muir, AJ, Pockros, P, Reddy, KR, Pedrosa, M, Larsen, L, Enejosa, J, and Howell, C. "High SVR Rates Among US Patients Regardless of Race or Ethnicity in HCV GT1 Patients Receiving the Label-Recommended Regimen of Ombitasvir/Paritaprevir/r plus Dasabuvir +/- Ribavirin: Integrated Safety and Efficacy Analysis." October 2015.