Andrew Joseph Muir, MD

Professor of Medicine
Chief, Division of Gastroenterology in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 03137B Hosp South, Durham, NC 27710
Phone (919) 684-2052
Email address andrew.muir@duke.edu
  • Hepatitis C 
  • Primary sclerosing cholangitis
  • Cirrhosis
  • Liver Transplantation
  • Clinical Trials
  • Healthcare disparities in liver disease 
  • Outcomes Research
In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Duke University, 1998 - 2000
  • Chief Medical Resident, Medicine, Duke University, 1997 - 1998
  • Fellow in Gastroenterology, Medicine, Duke University, 1996 - 1997
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2001
  • M.D., Duke University, 1993

Publications

Mayo, MJ, Wigg, AJ, Roberts, SK, Arnold, H, Hassanein, TI, Leggett, BA, Bate, JP, Weltman, M, Carey, EJ, Muir, AJ, McCaughan, G, Bollipo, SJ, Gordon, SC, Angus, PW, Riordan, S, Shiffman, ML, Young, E, Ling, L, Luo, J, Elliott, M, Rossi, S, DePaoli, AM, and Thompson, AJ. "NGM282, A Novel Variant of FGF-19, Demonstrates Biologic Activity in Primary Biliary Cirrhosis Patients with an Incomplete Response to Ursodeoxycholic Acid: Results of a Phase 2 Multicenter, Randomized, Double Blinded, Placebo Controlled Trial." 66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). San Francisco, CA. November 13, 2015 - November 17, 2015.: WILEY-BLACKWELL, October 1, 2015.

Scholars@Duke

Mayo, MJ, Wigg, AJ, Roberts, SK, Arnold, H, Hassanein, TI, Leggett, BA, Bate, JP, Weltman, M, Carey, EJ, Muir, AJ, McCaughan, G, Bollipo, SJ, Gordon, SC, Angus, PW, Riordan, S, Shiffman, ML, Young, E, Ling, L, Luo, J, Elliott, M, Rossi, S, DePaoli, AM, and Thompson, AJ. "NGM282, A Novel Variant of FGF-19, Demonstrates Biologic Activity in Primary Biliary Cirrhosis Patients with an Incomplete Response to Ursodeoxycholic Acid: Results of a Phase 2 Multicenter, Randomized, Double Blinded, Placebo Controlled Trial." 66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). San Francisco, CA. November 13, 2015 - November 17, 2015.: WILEY-BLACKWELL, October 1, 2015.

Scholars@Duke

Reau, N, Muir, AJ, Pockros, P, Reddy, KR, Pedrosa, M, Larsen, L, Enejosa, J, and Howell, C. "High SVR Rates Among US Patients Regardless of Race or Ethnicity in HCV GT1 Patients Receiving the Label-Recommended Regimen of Ombitasvir/Paritaprevir/r plus Dasabuvir +/- Ribavirin: Integrated Safety and Efficacy Analysis." October 2015.

Scholars@Duke

Harrison, SA, Goodman, ZD, Ratziu, V, Loomba, R, Diehl, AM, Lawitz, E, Hinrichsen, H, Bambha, K, Abdelmalek, MF, Myers, RP, Schall, REA, Subramanian, M, McHutchison, JG, Afdhal, NH, and Muir, AJ. "Serum lysyl oxidase-like-2 (sLOXL2) levels correlate with fibrosis stage in patients with nonalcoholic steatohepatitis (NASH)." October 2015.

Scholars@Duke

Ratziu, V, Sanyal, AJ, Loomba, R, Caldwell, SH, Ghalib, RH, Torres, DM, McCullough, AJ, Muir, AJ, Myers, RP, Schall, REA, Subramanian, M, McHutchison, JG, Bosch, J, Harrison, SA, and Abdelmalek, MF. "Characterization of insulin resistance in patients with advanced fibrosis due to nonalcoholic steatohepatitis (NASH)." October 2015.

Scholars@Duke

Charlton, M, Everson, GT, Flamm, SL, Kumar, P, Landis, C, Brown, RS, Fried, MW, Terrault, NA, O'Leary, JG, Vargas, HE, Kuo, A, Schiff, E, Sulkowski, MS, Gilroy, R, Watt, KD, Brown, K, Kwo, P, Pungpapong, S, Korenblat, KM, Muir, AJ, Teperman, L, Fontana, RJ, Denning, J, Arterburn, S, Dvory-Sobol, H, Brandt-Sarif, T, Pang, PS, McHutchison, JG, Reddy, KR, Afdhal, N, and SOLAR-1 Investigators, . "Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease." Gastroenterology 149, no. 3 (September 2015): 649-659.

PMID
25985734
Full Text

Shuldiner, SR, Gong, L, Muir, AJ, Altman, RB, and Klein, TE. "PharmGKB summary: peginterferon-α pathway." Pharmacogenetics and Genomics 25, no. 9 (September 2015): 465-474.

PMID
26111151
Full Text

Ahmad, T, Yin, P, Saffitz, J, Pockros, PJ, Lalezari, J, Shiffman, M, Freilich, B, Zamparo, J, Brown, K, Dimitrova, D, Kumar, M, Manion, D, Heath-Chiozzi, M, Wolf, R, Hughes, E, Muir, AJ, and Hernandez, AF. "Cardiac dysfunction associated with a nucleotide polymerase inhibitor for treatment of hepatitis C." Hepatology (Baltimore, Md.) 62, no. 2 (August 2015): 409-416.

PMID
25251156
Full Text

Muir, AJ. "Understanding the Complexities of Cirrhosis." Clinical Therapeutics 37, no. 8 (August 2015): 1822-1836. (Review)

PMID
26188836
Full Text

Giannini, EG, Afdhal, NH, Sigal, SH, Muir, AJ, Reddy, KR, Vijayaraghavan, S, Elkashab, M, Romero-Gómez, M, Dusheiko, GM, Iyengar, M, Vasey, SY, Campbell, FM, and Theodore, D. "Non-cirrhotic thrombocytopenic patients with hepatitis C virus: Characteristics and outcome of antiviral therapy." Journal of Gastroenterology and Hepatology 30, no. 8 (August 2015): 1301-1308.

PMID
25777337
Full Text

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