Barbara Dudley Alexander, MD

Professor of Medicine
Professor of Pathology
Campus mail 315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
Phone (919) 668-0789
Email address alexa011@mc.duke.edu

Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease.

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1998
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., East Carolina University, 1993

Publications

Healey, KR, Zhao, Y, Perez, WB, Lockhart, SR, Sobel, JD, Farmakiotis, D, Kontoyiannis, DP, Sanglard, D, Taj-Aldeen, SJ, Alexander, BD, Jimenez-Ortigosa, C, Shor, E, and Perlin, DS. "Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance." Nature communications 7 (March 29, 2016): 11128-.

PMID
27020939
Full Text

Husain, S, Sole, A, Alexander, BD, Aslam, S, Avery, R, Benden, C, Billaud, EM, Chambers, D, Danziger-Isakov, L, Fedson, S, Gould, K, Gregson, A, Grossi, P, Hadjiliadis, D, Hopkins, P, Luong, M-L, Marriott, DJE, Monforte, V, Muñoz, P, Pasqualotto, AC, Roman, A, Silveira, FP, Teuteberg, J, Weigt, S, Zaas, AK, Zuckerman, A, and Morrissey, O. "The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary." The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 35, no. 3 (March 2016): 261-282.

PMID
26970469
Full Text

Swamydas, M, Gao, J-L, Break, TJ, Johnson, MD, Jaeger, M, Rodriguez, CA, Lim, JK, Green, NM, Collar, AL, Fischer, BG, Lee, C-CR, Perfect, JR, Alexander, BD, Kullberg, B-J, Netea, MG, Murphy, PM, and Lionakis, MS. "CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival." Science translational medicine 8, no. 322 (January 2016): 322ra10-.

PMID
26791948
Full Text

Lamoth, F, and Alexander, BD. "Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds." Journal of clinical microbiology 53, no. 10 (October 2015): 3176-3181.

PMID
26202113
Full Text

Lamoth, F, and Alexander, BD. "Antifungal Susceptibility Testing to Predict Appropriate Initial Antifungal Therapy and Outcome in non-Aspergillus Invasive Mold Infections." October 2015.

Scholars@Duke

Lamoth, F, and Alexander, BD. "Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates." Antimicrobial agents and chemotherapy 59, no. 7 (July 2015): 4308-4311.

PMID
25896696
Full Text

McCarty, TP, Baddley, JW, Walsh, TJ, Alexander, BD, Kontoyiannis, DP, Perl, TM, Walker, R, Patterson, TF, Schuster, MG, Lyon, GM, Wingard, JR, Andes, DR, Park, BJ, Brandt, ME, Pappas, PG, and TRANSNET Investigators, . "Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET)." Medical mycology 53, no. 5 (June 2015): 440-446.

PMID
25908651
Full Text

Lamoth, F, Alexander, BD, Juvvadi, PR, and Steinbach, WJ. "Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species." The Journal of antimicrobial chemotherapy 70, no. 5 (May 2015): 1408-1411.

PMID
25558076
Full Text

Sun, H-Y, Alexander, BD, Huprikar, S, Forrest, GN, Bruno, D, Lyon, GM, Wray, D, Johnson, LB, Sifri, CD, Razonable, RR, Morris, MI, Stoser, V, Wagener, MM, and Singh, N. "Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 60, no. 1 (January 2015): 36-44.

PMID
25210020
Full Text

Brasier, AR, Zhao, Y, Spratt, HM, Wiktorowicz, JE, Ju, H, Wheat, LJ, Baden, L, Stafford, S, Wu, Z, Issa, N, Caliendo, AM, Denning, DW, Soman, K, Clancy, CJ, Nguyen, MH, Sugrue, MW, Alexander, BD, and Wingard, JR. "Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens." PloS one 10, no. 11 (January 2015): e0143165-.

PMID
26581097
Full Text

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