Barbara Dudley Alexander, MD

Professor of Medicine
Professor of Pathology
Campus mail 315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
Phone (919) 668-0789
Email address alexa011@mc.duke.edu

Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease.

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1998
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., East Carolina University, 1993

Publications

Sun, H-Y, Alexander, BD, Lortholary, O, Dromer, F, Forrest, GN, Lyon, GM, Somani, J, Gupta, KL, del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, John, GT, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Munoz, P, Kalil, AC, Garcia-Diaz, J, Orloff, S, House, AA, Houston, S, Wray, D, Huprikar, S, Johnson, LB, Humar, A, Razonable, RR, Husain, S, and Singh, N. "Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis." Clin Infect Dis 49, no. 11 (December 1, 2009): 1721-1728.

PMID
19886800
Full Text

Radack, KP, and Alexander, BD. "Prophylaxis of invasive mycoses in solid organ transplantation." Curr Infect Dis Rep 11, no. 6 (November 2009): 427-434.

PMID
19857381
Scholars@Duke

Pfaller, MA, Diekema, DJ, Ghannoum, MA, Rex, JH, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Espinel-Ingroff, A, Fowler, CL, Johnson, EM, Knapp, CC, Motyl, MR, Ostrosky-Zeichner, L, Sheehan, DJ, Walsh, TJ, and Clinical and Laboratory Standards Institute Antifungal Testing Subcommittee, . "Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods." J Clin Microbiol 47, no. 10 (October 2009): 3142-3146.

PMID
19692559
Full Text

Balajee, SA, Kano, R, Baddley, JW, Moser, SA, Marr, KA, Alexander, BD, Andes, D, Kontoyiannis, DP, Perrone, G, Peterson, S, Brandt, ME, Pappas, PG, and Chiller, T. "Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network." J Clin Microbiol 47, no. 10 (October 2009): 3138-3141.

PMID
19675215
Full Text

Pal, JD, Alexander, BD, Lodge, AJ, Blue, L, and Milano, CA. "Successful Management of Pump Pocket Infections in Patients with Implanted Left Ventricular Assist Devices." February 2009.

Scholars@Duke

Shi, S, Ashley, ESD, Alexander, BD, and Hickey, AJ. "Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles." AAPS PharmSciTech 10, no. 1 (2009): 129-137.

PMID
19189220
Full Text

Ostrosky-Zeichner, L, Rex, JH, Pfaller, MA, Diekema, DJ, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Ghannoum, MA, Knapp, CC, Sheehan, DJ, and Walsh, TJ. "Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method." Antimicrob Agents Chemother 52, no. 11 (November 2008): 4175-4177.

PMID
18809944
Full Text

Alexander, BD, Perfect, JR, Daly, JS, Restrepo, A, Tobón, AM, Patino, H, Hardalo, CJ, and Graybill, JR. "Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant." Transplantation 86, no. 6 (September 27, 2008): 791-796.

PMID
18813103
Full Text

Singh, N, Lortholary, O, Dromer, F, Alexander, BD, Gupta, KL, John, GT, del Busto, R, Klintmalm, GB, Somani, J, Lyon, GM, Pursell, K, Stosor, V, Munoz, P, Limaye, AP, Kalil, AC, Pruett, TL, Garcia-Diaz, J, Humar, A, Houston, S, House, AA, Wray, D, Orloff, S, Dowdy, LA, Fisher, RA, Heitman, J, Wagener, MM, Husain, S, and Cryptococcal Collaborative Transplant Study Group, . "Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings." Transplantation 86, no. 5 (September 15, 2008): 647-651.

PMID
18791444
Full Text

Pfaller, MA, Diekema, DJ, Ostrosky-Zeichner, L, Rex, JH, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Ghannoum, MA, Knapp, CC, Sheehan, DJ, and Walsh, TJ. "Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints." J Clin Microbiol 46, no. 8 (August 2008): 2620-2629.

PMID
18579718
Full Text

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