Crystal Cenell Tyson, MD

Assistant Professor of Medicine
Medical Instructor in the Department of Psychiatry and Behavioral Medicine
Campus mail 2727 Erwin Road, Suite 605, Durham, NC 27705
Phone (919) 660-6860
Email address crystal.simpson@duke.edu

As a board-certified nephrologist and a certified clinical hypertension specialist (ASH-SCH), I take care of patients with kidney disorders and/or high blood pressure. Patients with chronic kidney disease and high blood pressure have an increased risk for developing complications of cardiovascular disease, such as heart attacks, congestive heart failure, strokes, kidney failure requiring dialysis or a kidney transplant, and a shortened lifespan. My clinical focus is to slow the progression of chronic kidney disease and reduce complications from cardiovascular disease with lifestyle modification. I particularly enjoy treating patients with severe or difficult to control high blood pressure by focusing on finding an effective medication regimen that provides the least side effects, eliminating ineffective medications, simplifying medication schedules, and promoting healthy lifestyle behavior. I see patients 2 days per week in the Duke Nephrology Clinic and the Duke Nephrology Hypertension Clinic.

My research interests are to reduce racial and health disparities among patients with hypertension and chronic kidney disease using lifestyle modifications. My past and current research investigates the effects of diet (i.e., the DASH diet, sodium reduction), exercise, and weight loss on blood pressure and kidney function, as well as the effect of bilateral renal artery denervation on blood pressure.

Education and Training

  • Hypertension Fellowship, Department Of Medicine, Duke University School of Medicine, 2012 - 2013
  • Nephrology Fellowship, Department Of Medicine, Duke University School of Medicine, 2009 - 2012
  • Chief Resident, General Internal Medicine, St. John Hospital & Medical Center, 2008 - 2009
  • Residency, Generalinternal Medicine, St. John Hospital & Medical Center, 2005 - 2008
  • M.D., Wayne State University, School of Medicine, 2005

Publications

Bhavsar, Nrupen A., Clemontina A. Davenport, Lexie Zidanyue Yang, Sarah Peskoe, Julia J. Scialla, Rasheeda K. Hall, Crystal C. Tyson, et al. “Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.” Bmc Nephrol 22, no. 1 (November 11, 2021): 375. https://doi.org/10.1186/s12882-021-02594-6.

PMID
34763649
Full Text

Blumenthal, James A., Alan L. Hinderliter, Patrick J. Smith, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, et al. “Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.” Circulation 144, no. 15 (October 12, 2021): 1212–26. https://doi.org/10.1161/CIRCULATIONAHA.121.055329.

PMID
34565172
Full Text

Mitchell, Nia S., Bryan C. Batch, and Crystal C. Tyson. “Retrospective cohort study of changes in estimated glomerular filtration rate for patients prescribed a low carb diet.” Curr Opin Endocrinol Diabetes Obes 28, no. 5 (October 1, 2021): 480–87. https://doi.org/10.1097/MED.0000000000000673.

PMID
34392262
Full Text

Miller, Hailey N., Miriam B. Berger, Sandy Askew, Melissa C. Kay, Christina M. Hopkins, Meghana Sai Iragavarapu, Mia de Leon, et al. “The Nourish Protocol: A digital health randomized controlled trial to promote the DASH eating pattern among adults with hypertension.” Contemp Clin Trials 109 (October 2021): 106539. https://doi.org/10.1016/j.cct.2021.106539.

PMID
34400362
Full Text

Tyson, Crystal C., Alison Luciano, Jennifer L. Modliszewski, David L. Corcoran, James R. Bain, Michael Muehlbauer, Olga Ilkayeva, et al. “Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.” Am J Kidney Dis 78, no. 1 (July 2021): 38–47. https://doi.org/10.1053/j.ajkd.2020.10.015.

PMID
33810868
Full Text

Pourafshar, Shirin, Mira Nicchitta, Crystal C. Tyson, Laura P. Svetkey, David L. Corcoran, James R. Bain, Michael J. Muehlbauer, et al. “Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.” Nutrients 13, no. 6 (May 22, 2021). https://doi.org/10.3390/nu13061768.

PMID
34067295
Full Text

Tyson, Crystal C., Clemontina A. Davenport, Pao-Hwa Lin, Julia J. Scialla, Rasheeda Hall, Clarissa J. Diamantidis, Joseph Lunyera, et al. “DASH Diet and Blood Pressure Among Black Americans With and Without CKD: The Jackson Heart Study.” Am J Hypertens 32, no. 10 (September 24, 2019): 975–82. https://doi.org/10.1093/ajh/hpz090.

PMID
31187128
Full Text

Hall, Rasheeda K., Clemontina A. Davenport, Mario Sims, Cathleen Colón-Emeric, Tiffany Washington, Jennifer St Clair Russell, Jane Pendergast, et al. “Association of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study.” Bmc Nephrol 20, no. 1 (July 15, 2019): 262. https://doi.org/10.1186/s12882-019-1432-9.

PMID
31307430
Full Text

Böhm, Michael, Felix Mahfoud, Raymond R. Townsend, David E. Kandzari, Stuart Pocock, Christian Ukena, Michael A. Weber, et al. “Ambulatory heart rate reduction after catheter-based renal denervation in hypertensive patients not receiving anti-hypertensive medications: data from SPYRAL HTN-OFF MED, a randomized, sham-controlled, proof-of-concept trial.” Eur Heart J 40, no. 9 (March 1, 2019): 743–51. https://doi.org/10.1093/eurheartj/ehy871.

PMID
30608521
Full Text

Diamantidis, Clarissa J., Clemontina A. Davenport, Joseph Lunyera, Nrupen Bhavsar, Julia Scialla, Rasheeda Hall, Crystal Tyson, et al. “Low use of routine medical care among African Americans with high CKD risk: the Jackson Heart Study.” Bmc Nephrol 20, no. 1 (January 10, 2019): 11. https://doi.org/10.1186/s12882-018-1190-0.

PMID
30630437
Full Text

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