Endocrinology, Metabolism, and Nutrition

David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin at Madison, 1983

Grants

Publications

Capozzi, ME, Svendsen, B, Encisco, SE, Lewandowski, SL, Martin, MD, Lin, H, Jaffe, JL, Coch, RW, Haldeman, JM, MacDonald, PE, Merrins, MJ, D'Alessio, DA, and Campbell, JE. "β Cell tone is defined by proglucagon peptides through cAMP signaling." Jci Insight 4, no. 5 (March 7, 2019).

PMID
30720465
Full Text

Salehi, M, Gastaldelli, A, and D'Alessio, DA. "Role of vagal activation in postprandial glucose metabolism after gastric bypass in individuals with and without hypoglycaemia." Diabetes, Obesity & Metabolism (February 20, 2019).

PMID
30785669
Full Text

Salehi, M, Gastaldelli, A, and D'Alessio, DA. "Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery." Gut (February 16, 2019).

PMID
30772836
Full Text

Shariff, AI, Syed, S, Shelby, RA, Force, J, Clarke, JM, D'Alessio, D, and Corsino, L. "Novel cancer therapies and their association with diabetes." Journal of Molecular Endocrinology 62, no. 2 (February 2019): R187-R199. (Review)

PMID
30532995
Full Text

Coskun, T, Sloop, KW, Loghin, C, Alsina-Fernandez, J, Urva, S, Bokvist, KB, Cui, X, Briere, DA, Cabrera, O, Roell, WC, Kuchibhotla, U, Moyers, JS, Benson, CT, Gimeno, RE, D'Alessio, DA, and Haupt, A. "LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept." Molecular Metabolism 18 (December 2018): 3-14.

PMID
30473097
Full Text

Davies, MJ, D'Alessio, DA, Fradkin, J, Kernan, WN, Mathieu, C, Mingrone, G, Rossing, P, Tsapas, A, Wexler, DJ, and Buse, JB. "Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)." Diabetes Care 41, no. 12 (December 2018): 2669-2701.

PMID
30291106
Full Text

Rivero-Gutierrez, B, Haller, A, Holland, J, Yates, E, Khrisna, R, Habegger, K, Dimarchi, R, D'Alessio, D, and Perez-Tilve, D. "Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia." Molecular Metabolism 17 (November 2018): 28-38.

PMID
30170980
Full Text

Page, LC, Gastaldelli, A, Gray, SM, D'Alessio, DA, and Tong, J. "Interaction of GLP-1 and Ghrelin on Glucose Tolerance in Healthy Humans." Diabetes 67, no. 10 (October 2018): 1976-1985.

PMID
30065032
Full Text

Douros, JD, Lewis, AG, Smith, EP, Niu, J, Capozzi, M, Wittmann, A, Campbell, J, Tong, J, Wagner, C, Mahbod, P, Seeley, R, and D'Alessio, DA. "Enhanced Glucose Control Following Vertical Sleeve Gastrectomy Does Not Require a β-Cell Glucagon-Like Peptide 1 Receptor." Diabetes 67, no. 8 (August 2018): 1504-1511.

PMID
29759973
Full Text

Buse, JB, D'Alessio, DA, and Riddle, MC. "Can We RISE to the Challenge of Youth-Onset Type 2 Diabetes?." Diabetes Care 41, no. 8 (August 2018): 1560-1562.

PMID
29941499
Full Text

Pages