David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin at Madison, 1983

Publications

Aulinger, Benedikt A., Marta Perabo, Randy J. Seeley, Klaus G. Parhofer, and David A. D’Alessio. “Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats.” Am J Physiol Endocrinol Metab 318, no. 2 (February 1, 2020): E189–97. https://doi.org/10.1152/ajpendo.00298.2019.

PMID
31743041
Full Text

Herbst, Rebecca A., Onala T. Telford, John Hunting, W Michael Bullock, Erin Manning, Beatrice D. Hong, David A. D’Alessio, and Tracy L. Setji. “THE EFFECTS OF PERIOPERATIVE DEXAMETHASONE ON GLYCEMIC CONTROL AND POSTOPERATIVE OUTCOMES.” Endocr Pract 26, no. 2 (February 2020): 218–25. https://doi.org/10.4158/EP-2019-0252.

PMID
31652101
Full Text

Buse, John B., Deborah J. Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A. D’Alessio, and Melanie J. Davies. “2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).” Diabetologia 63, no. 2 (February 2020): 221–28. https://doi.org/10.1007/s00125-019-05039-w.

PMID
31853556
Full Text

Svendsen, Berit, Megan E. Capozzi, Jingjing Nui, Sarah A. Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A. D’Alessio, and Jonathan E. Campbell. “Pharmacological antagonism of the incretin system protects against diet-induced obesity.” Mol Metab 32 (February 2020): 44–55. https://doi.org/10.1016/j.molmet.2019.11.018.

PMID
32029229
Full Text

Capozzi, Megan E., Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, et al. “The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition.” Diabetes, January 31, 2020. https://doi.org/10.2337/db19-1216.

PMID
32005706
Full Text

Brehm, B., S. Summer, T. Jenkins, D. D’Alessio, and T. Inge. “Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females.” Surgery for Obesity and Related Diseases, January 1, 2020. https://doi.org/10.1016/j.soard.2020.01.025.

Full Text

Pettus, Jeremy H., David D’Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, and Keith B. Marschke. “Efficacy and Safety of the Glucagon Receptor Antagonist RVT-1502 in Type 2 Diabetes Uncontrolled on Metformin Monotherapy: A 12-Week Dose-Ranging Study.” Diabetes Care 43, no. 1 (January 2020): 161–68. https://doi.org/10.2337/dc19-1328.

PMID
31694861
Full Text

Douros, Jonathan D., Jenny Tong, and David A. D’Alessio. “The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control.” Endocr Rev 40, no. 5 (October 1, 2019): 1394–1423. https://doi.org/10.1210/er.2018-00183.

PMID
31241742
Full Text

Herman, Mark A., Jonathan E. Campbell, and David A. D’Alessio. “One small step for mice, one giant leap for GWAS?” J Clin Invest 129, no. 10 (October 1, 2019): 4083–85. https://doi.org/10.1172/JCI131650.

PMID
31498152
Full Text

Pages