David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington School of Medicine, 1987 - 1990
  • Resident, Temple University School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin, Madison, 1983

Publications

Buse, John B., Deborah J. Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A. D’Alessio, and Melanie J. Davies. “Erratum. 2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2020;43:487-493.” Diabetes Care 43, no. 7 (July 2020): 1670. https://doi.org/10.2337/dc20-er07.

PMID
32444453
Full Text

Gray, Sarah M., Yurong Xin, Elizabeth C. Ross, Bryanna M. Chazotte, Megan E. Capozzi, Kimberley El, Berit Svendsen, et al. “Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.” J Biol Chem, June 18, 2020. https://doi.org/10.1074/jbc.RA120.014368.

PMID
32554468
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Brehm, Bonnie, Suzanne Summer, Todd Jenkins, David D’Alessio, and Thomas Inge. “Thermic effect of food and resting energy expenditure after sleeve gastrectomy for weight loss in adolescent females.” Surg Obes Relat Dis 16, no. 5 (May 2020): 599–606. https://doi.org/10.1016/j.soard.2020.01.025.

PMID
32146085
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Capozzi, Megan E., Reilly W. Coch, Jepchumba Koech, Inna I. Astapova, Jacob B. Wait, Sara E. Encisco, Jonathan D. Douros, et al. “The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition.” Diabetes 69, no. 5 (May 2020): 882–92. https://doi.org/10.2337/db19-1216.

PMID
32005706
Full Text

Aulinger, Benedikt A., Marta Perabo, Randy J. Seeley, Klaus G. Parhofer, and David A. D’Alessio. “Rapid hepatic metabolism blunts the endocrine action of portally infused GLP-1 in male rats.” Am J Physiol Endocrinol Metab 318, no. 2 (February 1, 2020): E189–97. https://doi.org/10.1152/ajpendo.00298.2019.

PMID
31743041
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Herbst, Rebecca A., Onala T. Telford, John Hunting, W Michael Bullock, Erin Manning, Beatrice D. Hong, David A. D’Alessio, and Tracy L. Setji. “THE EFFECTS OF PERIOPERATIVE DEXAMETHASONE ON GLYCEMIC CONTROL AND POSTOPERATIVE OUTCOMES.” Endocr Pract 26, no. 2 (February 2020): 218–25. https://doi.org/10.4158/EP-2019-0252.

PMID
31652101
Full Text

Buse, John B., Deborah J. Wexler, Apostolos Tsapas, Peter Rossing, Geltrude Mingrone, Chantal Mathieu, David A. D’Alessio, and Melanie J. Davies. “2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).” Diabetologia 63, no. 2 (February 2020): 221–28. https://doi.org/10.1007/s00125-019-05039-w.

PMID
31853556
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Svendsen, Berit, Megan E. Capozzi, Jingjing Nui, Sarah A. Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A. D’Alessio, and Jonathan E. Campbell. “Pharmacological antagonism of the incretin system protects against diet-induced obesity.” Mol Metab 32 (February 2020): 44–55. https://doi.org/10.1016/j.molmet.2019.11.018.

PMID
32029229
Full Text

Pettus, Jeremy H., David D’Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, and Keith B. Marschke. “Efficacy and Safety of the Glucagon Receptor Antagonist RVT-1502 in Type 2 Diabetes Uncontrolled on Metformin Monotherapy: A 12-Week Dose-Ranging Study.” Diabetes Care 43, no. 1 (January 2020): 161–68. https://doi.org/10.2337/dc19-1328.

PMID
31694861
Full Text

Pages