Endocrinology, Metabolism, and Nutrition

David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington, School of Medicine, 1987 - 1990
  • Resident, Temple University, School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin - Madison, 1983

Grants

Publications

Kumar, Nitya, and David A. D’Alessio. “Slow and steady wins the race: 25 years developing the GLP-1 receptor as an effective target for weight loss.” J Clin Endocrinol Metab, May 10, 2022. https://doi.org/10.1210/clinem/dgac276.

PMID
35536590
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Campbell, Jonathan E., Jacqueline L. Beaudry, Berit Svendsen, Laurie L. Baggio, Andrew N. Gordon, John R. Ussher, Chi Kin Wong, et al. “GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue.” Diabetes 71, no. 5 (May 1, 2022): 1115–27. https://doi.org/10.2337/db21-1166.

PMID
35192688
Full Text

D’Alessio, David, and Cris Slentz. “Data from: GLP-1 receptor blockade reduces stimulated insulin secretion in fasted subjects with low circulating GLP-1,” January 26, 2022. https://doi.org/10.7924/r47s7t64c.

Full Text

Ozer, Imran, Anna Slezak, Jeffrey Everitt, Xinghai Li, Nikita Zakharov, Joel Collier, Jonathan Campbell, David D’Alessio, and Ashutosh Chilkoti. “Injectable non-immunogenic PEG-like conjugate that forms a subcutaneous depot and enables sustained delivery of a peptide drug,” July 28, 2021. https://doi.org/10.21203/rs.3.rs-737658/v1.

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GRAY, SARAH M., G. U. O. -. F. A. N. G. ZHANG, W. I. L. L. I. A. M. BENNETT, J. E. N. N. Y. TONG, J. O. N. A. T. H. A. N. CAMPBELL, and DAVID A. D’ALESSIO. “198-OR: The Stimulatory Effect of Glucagon on Insulin Secretion Is Glucose Dependent in Healthy Human Subjects.” In Diabetes, Vol. 70. American Diabetes Association, 2021. https://doi.org/10.2337/db21-198-or.

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ILAIWY, A. M. R. O., A. D. A. M. MINCEY, JAMES R. BAIN, M. I. C. H. A. E. L. MUEHLBAUER, J. O. N. A. T. H. A. N. CAMPBELL, and DAVID A. D’ALESSIO. “781-P: Beyond Glucosuria: Urine Metabolome Signature Associated with Dapagliflozin in Wild-Type Mice.” In Diabetes, Vol. 70. American Diabetes Association, 2021. https://doi.org/10.2337/db21-781-p.

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Schaffer, Anna E., David A. D’Alessio, and John R. Guyton. “Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets.” J Clin Lipidol 15, no. 3 (May 2021): 525–26. https://doi.org/10.1016/j.jacl.2021.04.010.

PMID
34030981
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El, K., S. M. Gray, M. E. Capozzi, E. R. Knuth, E. Jin, B. Svendsen, A. Clifford, et al. “GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells.” Sci Adv 7, no. 11 (March 2021). https://doi.org/10.1126/sciadv.abf1948.

PMID
33712466
Full Text

Alonge, Kimberly M., David A. D’Alessio, and Michael W. Schwartz. “Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes.” Diabetologia 64, no. 1 (January 2021): 5–14. https://doi.org/10.1007/s00125-020-05293-3.

PMID
33043401
Full Text

Alonge, Kimberly M., David A. D’Alessio, and Michael W. Schwartz. “Correction to: Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes.” Diabetologia 64, no. 1 (January 2021): 259. https://doi.org/10.1007/s00125-020-05321-2.

PMID
33175179
Full Text

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