David A D'Alessio, MD

Professor of Medicine
Chief, Division of Endocrinology and Metabolism
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-4005
Email address david.d'alessio@duke.edu

Education and Training

  • Research Fellowship, Metabolism, Endocrinology And Nutrition, University of Washington, School of Medicine, 1987 - 1990
  • Resident, Temple University, School of Medicine, 1983 - 1986
  • M.D., University of Wisconsin - Madison, 1983

Publications

Pettus, Jeremy H., David D’Alessio, Juan P. Frias, Eric G. Vajda, James D. Pipkin, Julio Rosenstock, Gretchen Williamson, Miriam A. Zangmeister, Lin Zhi, and Keith B. Marschke. “Efficacy and Safety of the Glucagon Receptor Antagonist RVT-1502 in Type 2 Diabetes Uncontrolled on Metformin Monotherapy: A 12-Week Dose-Ranging Study.” Diabetes Care 43, no. 1 (January 2020): 161–68. https://doi.org/10.2337/dc19-1328.

PMID
31694861
Full Text

Douros, Jonathan D., Jenny Tong, and David A. D’Alessio. “The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control.” Endocr Rev 40, no. 5 (October 1, 2019): 1394–1423. https://doi.org/10.1210/er.2018-00183.

PMID
31241742
Full Text

Herman, Mark A., Jonathan E. Campbell, and David A. D’Alessio. “One small step for mice, one giant leap for GWAS?” J Clin Invest 129, no. 10 (October 1, 2019): 4083–85. https://doi.org/10.1172/JCI131650.

PMID
31498152
Full Text

Angellotti, Edith, David D’Alessio, Bess Dawson-Hughes, Yan Chu, Jason Nelson, Peter Hu, Robert M. Cohen, and Anastassios G. Pittas. “Effect of vitamin D supplementation on cardiovascular risk in type 2 diabetes.” Clin Nutr 38, no. 5 (October 2019): 2449–53. https://doi.org/10.1016/j.clnu.2018.10.003.

PMID
30352748
Full Text

Salehi, Marzieh, Amalia Gastaldelli, and David A. D’Alessio. “Beta-cell sensitivity to insulinotropic gut hormones is reduced after gastric bypass surgery.” Gut 68, no. 10 (October 2019): 1838–45. https://doi.org/10.1136/gutjnl-2018-317760.

PMID
30772836
Full Text

Douros, Jonathan D., Jingjing Niu, Sophia Sdao, Trillian Gregg, Matthew J. Merrins, Jonathan Campbell, Jenny Tong, and David D’Alessio. “Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control.” Mol Metab 28 (October 2019): 144–50. https://doi.org/10.1016/j.molmet.2019.07.003.

PMID
31326351
Full Text

Capozzi, Megan E., Jacob B. Wait, Jepchumba Koech, Andrew N. Gordon, Reilly W. Coch, Berit Svendsen, Brian Finan, David A. D’Alessio, and Jonathan E. Campbell. “Glucagon lowers glycemia when β-cells are active.” Jci Insight 5 (July 23, 2019). https://doi.org/10.1172/jci.insight.129954.

PMID
31335319
Full Text

GILROY, CASLIN A., M. E. G. A. N. CAPOZZI, JONATHAN C. SU, J. E. N. N. Y. TONG, DAVID A. D’ALESSIO, J. O. N. A. T. H. A. N. CAMPBELL, and A. S. H. U. T. O. S. H. CHILKOTI. “1016-P: A Novel GLP-1 and FGF-21 Dual Agonist Drug Protects Mice from Obesity and Hyperglycemia.” In Diabetes, Vol. 68. American Diabetes Association, 2019. https://doi.org/10.2337/db19-1016-p.

Full Text

Salehi, Marzieh, Amalia Gastaldelli, and David A. D’Alessio. “Role of vagal activation in postprandial glucose metabolism after gastric bypass in individuals with and without hypoglycaemia.” Diabetes Obes Metab 21, no. 6 (June 2019): 1513–17. https://doi.org/10.1111/dom.13676.

PMID
30785669
Full Text

Pages