David Isaias Ortiz-Melo, MD

Assistant Professor of Medicine
Campus mail DUMC 103015, Durham, NC 27710
Email address david.ortiz-melo@duke.edu

I enjoy practicing nephrology and taking care of patient with kidney disorders. As a clinician-educator in the Division of Nephrology, my clinical practice mainly focuses on the management of uncontrolled high blood pressure, chronic kidney disease, acute kidney injury and fluid and electrolyte disorders. I have particular interest in the evaluation and management of kidney disease affecting patients with cancer (onco-nephrology). In the inpatient setting, my clinical activities are focused on consultative nephrology and maintenance dialysis.  In the outpatient setting, I see patients two days weekly through the Private Diagnostic Clinic. In addition, I am a rounding nephrologist at three outpatient dialysis units.

Education and Training

  • Chief Medical Resident, Wayne State University School of Medicine, 2009 - 2010
  • Resident, Wayne State University School of Medicine, 2007 - 2009
  • Intern, Wayne State University School of Medicine, 2006 - 2007
  • M.D., Instituto Tecnologico de Santo Domingo (Dominican Republic), 2004

Publications

Ortiz-Melo, DI, and Kovalik, EC. "Methods of Hemodialysis Anticoagulation." In Handbook of Dialysis Therapy: Fifth Edition, 191-204.e1. November 8, 2016.

Full Text

Ortiz-Melo, DI, and Gurley, SB. "Angiotensin converting enzyme 2 and the kidney." Current opinion in nephrology and hypertension 25, no. 1 (January 2016): 59-66. (Review)

PMID
26575394
Full Text

Ortiz-Melo, DI, and Spurney, RF. "Special deLIVERy: podocyte injury promotes renal angiotensin II generation from liver-derived angiotensinogen." Kidney International 85, no. 5 (May 2014): 1009-1011.

PMID
24786873
Full Text

Wysocki, J, Ortiz-Melo, DI, Mattocks, NK, Xu, K, Prescott, J, Evora, K, Ye, M, Sparks, MA, Haque, SK, Batlle, D, and Gurley, SB. "ACE2 deficiency increases NADPH-mediated oxidative stress in the kidney." Physiological Reports 2, no. 3 (March 2014).

PMID
24760518
Full Text

Lehrich, RW, Ortiz-Melo, DI, Patel, MB, and Greenberg, A. "Role of vaptans in the management of hyponatremia." Am J Kidney Dis 62, no. 2 (August 2013): 364-376. (Review)

PMID
23725974
Full Text

Ortiz-Melo, D, and Coffman, TM. "A trip to inner space: insights into salt balance from cosmonauts." Cell Metab 17, no. 1 (January 8, 2013): 1-2.

PMID
23312276
Full Text

Lehrich, RW, Ortiz-Melo, DI, Patel, MB, and Greenberg, A. "Role of vaptans in the management of hyponatremia." American Journal of Kidney Diseases 62, no. 2 (2013): 364-376.

Full Text

Corsino, L, Rocha-Goldberg, MP, Batch, BC, Ortiz-Melo, DI, Bosworth, HB, and Svetkey, LP. "The Latino Health Project: pilot testing a culturally adapted behavioral weight loss intervention in obese and overweight Latino adults." Ethnicity & Disease 22, no. 1 (January 2012): 51-57.

PMID
22774309
Scholars@Duke