David William Butterly, MD

Associate Professor of Medicine
Campus mail 2424 Erwin Road - Suite 605, Durham, NC 27705
Phone (919) 660-6865
Email address butte001@mc.duke.edu

As a Clinician and Clinical Researcher in the Division of Nephrology my practice is mainly focussed on patients with end stage renal disease. I am co-Director of a maintenance hemodialysis unit which cares for approximately 110 patients on maintenance hemodialysis. In addition, I see patients three days weekly through the Private Diagnostic Clinic. We see a variety of consultative nephrology problems, but our major focus remains Aend stage renal disease and renal transplantation@. In the Renal Transplant Clinic, we see patients both pre- and post-transplant. Over the last two years we have transplanted 90-100 patients annually and care for several hundred other patients who are on the active transplant list.

My research interests thus relate primarily to end stage renal disease. In the dialysis unit we are currently involved in a multi-center NIH-sponsored trial called the AHEMO Trial@, which is looking at causes of long-term morbidity and mortality in the dialysis population and the effect on the dialysis prescription. In addition, our group has been active in maintenance of long-term hemodialysis access in the prospective of monitoring of vascular access to extend long-term graft survival. In the transplantation arena, we will soon be stating another multi-center trial to evaluate a new anti-lymphocyte antibody for the treatment of acute cellular rejection. This will be a multi-center randomized trial evaluating this new antibody versus OKT-3, which is currently standard of care. We are also interested in bone disease after transplantation and the prevention of acute rejection with other pharmacologic mechanisms and are establishing trials and interventions to evaluate these.

KEY WORDS:
End stage renal disease, vascular access, renal transplantation, post-transplantation osseous disorders, consultative Nephrology.

Education and Training

  • Fellow in Nephrology, Medicine, Duke University, 1990 - 1992
  • Medical Resident, Medicine, Duke University, 1987 - 1990
  • M.D., Duke University, 1987

Publications

Gage, SM, Katzman, HE, Ross, JR, Hohmann, SE, Sharpe, CA, Butterly, DW, and Lawson, JH. "Multi-center experience of 164 consecutive Hemodialysis Reliable Outflow [HeRO] graft implants for hemodialysis treatment." Eur J Vasc Endovasc Surg 44, no. 1 (July 2012): 93-99.

PMID
22580402
Full Text

Novak, JE, Butterly, DW, Desai, DM, Marroquin, CE, and Greenberg, A. "Familial hypocalciuric hypercalcemia in the donor and recipient of a living related donor kidney transplant." Am J Transplant 7, no. 3 (March 2007): 718-721.

PMID
17217434
Full Text

Plumb, TJ, Greenberg, A, Smith, SR, Butterly, DW, Pham, TTN, Fields, TA, and Howell, DN. "Postinfectious glomerulonephritis in renal allograft recipients." Transplantation 82, no. 9 (November 15, 2006): 1224-1228.

PMID
17102776
Full Text

Szczech, LA, Anderson, A, Ramers, C, Engeman, J, Ellis, M, Butterly, D, and Howell, DN. "The uncertain significance of anti-glomerular basement membrane antibody among HIV-infected persons with kidney disease." Am J Kidney Dis 48, no. 4 (October 2006): e55-e59.

PMID
16997046
Full Text

Hanish, SI, Petersen, RP, Collins, BH, Tuttle-Newhall, J, Marroquin, CE, Kuo, PC, Butterly, DW, Smith, SR, and Desai, DM. "Obesity predicts increased overall complications following pancreas transplantation." Transplant Proc 37, no. 8 (October 2005): 3564-3566.

PMID
16298662
Full Text

Lehrich, RW, Rocha, PN, Reinsmoen, N, Greenberg, A, Butterly, DW, Howell, DN, and Smith, SR. "Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation." Hum Immunol 66, no. 4 (April 2005): 350-358.

PMID
15866697
Full Text

Collins, BH, Marroquin, CE, Tuttle-Newhall, JE, Kuo, PC, Preminger, GM, and Butterly, DW. "Acute kidney transplant failure following transurethral bladder polyp fulguration." J Natl Med Assoc 97, no. 3 (March 2005): 414-416.

PMID
15779509
Scholars@Duke

Allon, M, Radeva, M, Bailey, J, Beddhu, S, Butterly, D, Coyne, DW, Depner, TA, Gassman, JJ, Kaufman, AM, Kaysen, GA, Lewis, JA, and Schwab, SJ. "The spectrum of infection-related morbidity in hospitalized haemodialysis patients." Nephrology Dialysis Transplantation 20 (2005): 1180-1186.

PMID
15769823
Full Text

Kurella, M, Butterly, DW, and Smith, SR. "Post transplant erythrocytosis in hypercalcemic renal transplant recipients." Am J Transplant 3, no. 7 (July 2003): 873-877.

PMID
12814479
Scholars@Duke

Rocha, PN, Butterly, DW, Greenberg, A, Reddan, DN, Tuttle-Newhall, J, Collins, BH, Kuo, PC, Reinsmoen, N, Fields, T, Howell, DN, and Smith, SR. "Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection." Transplantation 75, no. 9 (May 15, 2003): 1490-1495.

PMID
12792502
Full Text

Pages