Eric Leo Eisenstein

Associate Professor in Medicine
Associate Professor in Community and Family Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt St, Durham, NC 27705
Phone (919) 668-8984
Email address eisen006@mc.duke.edu

Research Interests:

Dr. Eisenstein is a member of the Duke Clinical Research Institute’s Outcomes Research and Assessment Group, with a special interest in understanding the relationships between complex interventions in health care systems and the long-term clinical and economic outcomes of patients. He has served as Principal Investigator for phase II, III, and IV economic and quality of life studies conducted alongside randomized clinical trials in cardiovascular, emergency, pulmonary, and vascular medicine and surgery. He also has conducted health technology evaluations making use of innovative research methods designed to better understand key relationships in observation (non-randomized) patient data. This work has included evaluations of the long-term clinical outcomes of coronary artery disease patients receiving drug-eluting vs. bare metal intracoronary stents, and how the use of clopidogrel changes those relationships. He also has conducted several studies assessing factors contributing to the costs of and evaluating different design considerations for multi-center randomized clinical trials.

In addition to his working in traditional health technology evaluation, Dr. Eisenstein has an interest in evaluating information technologies as interventions in health care systems. In this regard, he has collaborated in the design and conduct of large-scale, randomized clinical trials to evaluate clinical decision support systems. The research objective in these studies has been to develop methods for evaluating health information technologies in practice-based settings using a “tool kit” of inexpensive, yet highly scalable methods that make use of data sets created as a byproduct of normal clinical and administrative operations. The use of these evaluation methods has been demonstrated in four clinical trials that include care process, clinical, economic, and quality of life measurements.

Education and Training

  • D.B.A., Cleveland State University, 1995

Publications

Levitan, B, Getz, K, Eisenstein, EL, Goldberg, M, Harker, M, Hesterlee, S, Patrick-Lake, B, Roberts, JN, and DiMasi, J. "Assessing the Financial Value of Patient Engagement." Therapeutic Innovation & Regulatory Science (July 17, 2017): 216847901771671-216847901771671.

Full Text

Nordo, AH, Eisenstein, EL, Hawley, J, Vadakkeveedu, S, Pressley, M, Pennock, J, and Sanderson, I. "A comparative effectiveness study of eSource used for data capture for a clinical research registry." International journal of medical informatics 103 (July 2017): 89-94.

PMID
28551007
Full Text

Levitan, B, Getz, KA, Eisenstein, EL, Goldberg, M, Harker, M, Hesterlee, SE, Patrick-Lake, B, Roberts, J, and DiMasi, JA. "ASSESSING THE FINANCIAL VALUE OF PATIENT ENGAGEMENT." May 2017.

Scholars@Duke

Eisenstein, EL, Nordo, AH, and Zozus, MN. "Using Medical Informatics to Improve Clinical Trial Operations." Studies in health technology and informatics 234 (January 2017): 93-97.

PMID
28186022
Scholars@Duke

Wagner, M, Wagner, L, Wagner, C, Bell, SJ, Nicholson, BW, Strauss, DG, Warren, S, Pahlm, O, Bacharova, L, Lipton, J, Eisenstein, E, Kudaiberdieva, G, and Hakacova, N. "In memory of Professor Galen S. Wagner M.D., Ph.D. (1939–2016): our mentor, colleague and friend." Journal of Electrocardiology 50, no. 1 (January 2017): 3-4.

Full Text

Bacharova, L, Bell, SJ, Lipton, J, Eisenstein, E, Kudaiberdieva, G, Wagner, M, Mozos, I, Misak, A, and Hakacova, N. "The Research Practicum and International Research Interdisciplinary School (IRIS) initiatives: In memory of Professor Galen S. Wagner M.D., PhD." Journal of Electrocardiology 50, no. 1 (January 2017): 5-10.

Full Text

Ammenwerth, E, De Keizer, N, Brender Mcnair, J, Craven, CK, Eisenstein, E, Georgiou, A, Khairat, S, Magrabi, F, Nykänen, P, Otero, P, Rigby, M, Scott, P, and Weir, C. "How to teach health it evaluation: Recommendations for health IT evaluation courses." January 1, 2017.

Full Text

Eisenstein, EL, Willis, JM, Edwards, R, Anstrom, KJ, Kawamoto, K, Fiol, GD, Johnson, FS, and Lobach, DF. "Randomized Trial of Population-Based Clinical Decision Support to Facilitate Care Transitions." Studies in health technology and informatics 234 (January 2017): 98-103.

PMID
28186023
Scholars@Duke

Eisenstein, E, Levitan, B, Getz, K, Patrick-Lake, B, and Harker, M. "Identifying And Valuing Patient Group Engagement Methods." May 2016.

Full Text

Eisenstein, EL. "Commentary on Sertkaya et al. and Larson et al." Clinical trials (London, England) 13, no. 2 (April 2016): 137-139.

PMID
26908542
Full Text

Pages