Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Jones, WS, Clare, RM, Chiswell, K, Perera, D, French, JK, Kumar, AS, Blaxill, J, Pijls, N, Mills, J, Ohman, EM, and Patel, MR. "The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial." Clinical cardiology 38, no. 1 (January 2015): 25-31.

PMID
25488040
Full Text

Goto, K, Lansky, AJ, Ng, VG, Pietras, C, Nargileci, E, Mehran, R, Parise, H, Feit, F, Ohman, EM, White, HD, Bertrand, ME, Desmet, W, Hamon, M, and Stone, GW. "Prognostic value of angiographic lesion complexity in patients with acute coronary syndromes undergoing percutaneous coronary intervention (from the acute catheterization and urgent intervention triage strategy trial)." The American journal of cardiology 114, no. 11 (December 2014): 1638-1645.

PMID
25312637
Full Text

Udell, JA, Steg, PG, Scirica, BM, Eagle, KA, Ohman, EM, Goto, S, Alsheikh-Ali, AA, Porath, A, Corbalan, R, Umez-Eronini, AA, Hoffman, EB, Wilson, PWF, Bhatt, DL, and Reduction of Atherothrombosis for Continued Health (REACH) Registry Investigators, . "Metabolic syndrome, diabetes mellitus, or both and cardiovascular risk in outpatients with or at risk for atherothrombosis." European journal of preventive cardiology 21, no. 12 (December 2014): 1531-1540.

PMID
23918840
Full Text

Amsterdam, EA, Wenger, NK, Brindis, RG, Casey, DE, Ganiats, TG, Holmes, DR, Jaffe, AS, Jneid, H, Kelly, RF, Kontos, MC, Levine, GN, Liebson, PR, Mukherjee, D, Peterson, ED, Sabatine, MS, Smalling, RW, Zieman, SJ, and ACC/AHA Task Force Members, . "2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 130, no. 25 (December 2014): e344-e426.

PMID
25249585
Full Text

Amsterdam, EA, Wenger, NK, Brindis, RG, Casey, DE, Ganiats, TG, Holmes, DR, Jaffe, AS, Jneid, H, Kelly, RF, Kontos, MC, Levine, GN, Liebson, PR, Mukherjee, D, Peterson, ED, Sabatine, MS, Smalling, RW, Zieman, SJ, ACC/AHA Task Force Members, , and Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons, . "2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 130, no. 25 (December 2014): 2354-2394.

PMID
25249586
Full Text

Wijeysundera, DN, Duncan, D, Nkonde-Price, C, Virani, SS, Washam, JB, Fleischmann, KE, Fleisher, LA, and ACC/AHA Task Force Members, . "Perioperative beta blockade in noncardiac surgery: a systematic review for the 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 130, no. 24 (December 2014): 2246-2264. (Review)

PMID
25085964
Full Text

Fleisher, LA, Fleischmann, KE, Auerbach, AD, Barnason, SA, Beckman, JA, Bozkurt, B, Davila-Roman, VG, Gerhard-Herman, MD, Holly, TA, Kane, GC, Marine, JE, Nelson, MT, Spencer, CC, Thompson, A, Ting, HH, Uretsky, BF, and Wijeysundera, DN. "2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 130, no. 24 (December 2014): e278-e333.

PMID
25085961
Full Text

Fleisher, LA, Fleischmann, KE, Auerbach, AD, Barnason, SA, Beckman, JA, Bozkurt, B, Davila-Roman, VG, Gerhard-Herman, MD, Holly, TA, Kane, GC, Marine, JE, Nelson, MT, Spencer, CC, Thompson, A, Ting, HH, Uretsky, BF, and Wijeysundera, DN. "2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines." Circulation 130, no. 24 (December 2014): 2215-2245.

PMID
25085962
Full Text

January, CT, Wann, LS, Alpert, JS, Calkins, H, Cigarroa, JE, Cleveland, JC, Conti, JB, Ellinor, PT, Ezekowitz, MD, Field, ME, Murray, KT, Sacco, RL, Stevenson, WG, Tchou, PJ, Tracy, CM, Yancy, CW, and ACC/AHA Task Force Members, . "2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society." Circulation 130, no. 23 (December 2014): e199-e267.

PMID
24682347
Full Text

January, CT, Wann, LS, Alpert, JS, Calkins, H, Cigarroa, JE, Cleveland, JC, Conti, JB, Ellinor, PT, Ezekowitz, MD, Field, ME, Murray, KT, Sacco, RL, Stevenson, WG, Tchou, PJ, Tracy, CM, Yancy, CW, and ACC/AHA Task Force Members, . "2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society." Circulation 130, no. 23 (December 2014): 2071-2104.

PMID
24682348
Full Text

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