Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Song, Hongshuo, Bhavna Hora, Elena E. Giorgi, Amit Kumar, Fangping Cai, Tanmoy Bhattacharya, Alan S. Perelson, and Feng Gao. “Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences..” Sci Rep 6 (December 2, 2016). https://doi.org/10.1038/srep38130.

PMID
27909304
Full Text

Bradley, Todd, Ashley Trama, Nancy Tumba, Elin Gray, Xiaozhi Lu, Navid Madani, Fatemeh Jahanbakhsh, et al. “Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity..” Ebiomedicine 12 (October 2016): 196–207. https://doi.org/10.1016/j.ebiom.2016.08.045.

PMID
27612593
Full Text

Wang, Chu, Chunlai Jiang, Nan Gao, Kaikai Zhang, Donglai Liu, Wei Wang, Zhe Cong, et al. “Partial Protection from Intravenous Challenge by an Integration-defective SIV Vaccine.” In Aids Research and Human Retroviruses, 32:325–325. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

Smith, Claire E. P., Josh Eudailey, Amit Kumar, Lisa Stamper, Elena Giorgi, Genevieve Fouda, Erin Mcguire, Feng Gao, and Sallie Permar. “Infant Peripartum Transmitted-founder HIV-1 Variants are Resistant to Autologous Maternal Plasma Neutralization.” In Aids Research and Human Retroviruses, 32:87–87. MARY ANN LIEBERT, INC, 2016.

Scholars@Duke

Li, Xiaojun, Peihu Fan, Chunlai Jiang, Tonghui Ma, Xianghui Yu, Wei Kong, and Feng Gao. “High-Frequency Illegitimate Strand Transfers of Nascent DNA Fragments During Reverse Transcription Result in Defective Retrovirus Genomes..” J Acquir Immune Defic Syndr 72, no. 4 (August 1, 2016): 353–62. https://doi.org/10.1097/QAI.0000000000000952.

PMID
26885810
Full Text

Moody, M Anthony, Isabela Pedroza-Pacheco, Nathan A. Vandergrift, Cecilia Chui, Krissey E. Lloyd, Robert Parks, Kelly A. Soderberg, et al. “Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies..” Sci Immunol 1, no. 1 (July 29, 2016). https://doi.org/10.1126/sciimmunol.aag0851.

PMID
28783677
Full Text

Hora, B., N. Gulzar, Y. Chen, F. Cai, C. Su, K. Karagiannis, K. Smith, et al. “Streamlined quasispecies and subtype analysis of HIV-1 sequences generated by high-throughput sequencing using the high-performance integrated virtual environment (HIVE).” In Journal of the International Aids Society, Vol. 19. JOHN WILEY & SONS LTD, 2016.

Scholars@Duke

Rademeyer, Cecilia, Bette Korber, Michael S. Seaman, Elena E. Giorgi, Ruwayhida Thebus, Alexander Robles, Daniel J. Sheward, et al. “Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization..” Plos Pathog 12, no. 7 (July 2016). https://doi.org/10.1371/journal.ppat.1005742.

PMID
27434311
Full Text

Zhang, Ruijun, Laurent Verkoczy, Kevin Wiehe, S. Munir Alam, Nathan I. Nicely, Sampa Santra, Todd Bradley, et al. “Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages..” Sci Transl Med 8, no. 336 (April 27, 2016). https://doi.org/10.1126/scitranslmed.aaf0618.

PMID
27122615
Full Text

Bonsignori, Mattia, Tongqing Zhou, Zizhang Sheng, Lei Chen, Feng Gao, M Gordon Joyce, Gabriel Ozorowski, et al. “Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody..” Cell 165, no. 2 (April 7, 2016): 449–63. https://doi.org/10.1016/j.cell.2016.02.022.

PMID
26949186
Full Text

Pages