Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Chen, Yue, Ning Li, Tong Zhang, Xiaojie Huang, Fangping Cai, Nathan Vandergrift, Ruolei Xin, et al. “Comprehensive Characterization of the Transmitted/Founder env Genes From a Single MSM Cohort in China..” J Acquir Immune Defic Syndr 69, no. 4 (August 1, 2015): 403–12. https://doi.org/10.1097/QAI.0000000000000649.

PMID
25886933
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Santra, Sampa, Georgia D. Tomaras, Ranjit Warrier, Nathan I. Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, et al. “Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques..” Plos Pathog 11, no. 8 (August 2015). https://doi.org/10.1371/journal.ppat.1005042.

PMID
26237403
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Ma, Ying-Wei, Shu-Bin Hao, Le-le Sun, Jing Li, Qiao Qiao, Feng Gao, Li Zhao, Xue-Jie Yu, Zhi-Yu Wang, and Hong-Ling Wen. “Construction and characterization of infectious cDNA clones of enterovirus 71 (EV71)..” Virol Sin 30, no. 4 (August 2015): 305–8. https://doi.org/10.1007/s12250-015-3614-3.

PMID
26271283
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Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission..” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.

PMID
26053661
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Demarco, Todd, Wes Rountree, Bhavna Hora, Yue Chen, Sarah Keinonen, Laura Racz, Lily Daniell, et al. “HIV-1 subtype C is significantly more infectious than other subtypes.” Journal of the International Aids Society 18 (July 1, 2015). https://doi.org/10.7448/IAS.18.5.20462.

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Fan, Peihu, Xiaojun Li, Shiyang Sun, Weiheng Su, Dong An, Feng Gao, Wei Kong, and Chunlai Jiang. “Identification of a common epitope between enterovirus 71 and human MED25 proteins which may explain virus-associated neurological disease..” Viruses 7, no. 4 (March 27, 2015): 1558–77. https://doi.org/10.3390/v7041558.

PMID
25826188
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Fan, Peihu, Xiaojun Li, Weiheng Su, Wei Kong, Xianggui Kong, Zhenxin Wang, Youchun Wang, Chunlai Jiang, and Feng Gao. “Enhanced Sensitivity for Detection of HIV-1 p24 Antigen by a Novel Nuclease-Linked Fluorescence Oligonucleotide Assay..” Plos One 10, no. 4 (2015). https://doi.org/10.1371/journal.pone.0125701.

PMID
25915630
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Liu, Donglai, Tao Zuo, Bhavna Hora, Hongshuo Song, Wei Kong, Xianghui Yu, Nilu Goonetilleke, et al. “Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation..” Retrovirology 11 (November 19, 2014). https://doi.org/10.1186/s12977-014-0101-0.

PMID
25407514
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Hraber, Peter, Bette T. Korber, Alan S. Lapedes, Robert T. Bailer, Michael S. Seaman, Hongmei Gao, Kelli M. Greene, et al. “Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies..” J Virol 88, no. 21 (November 2014): 12623–43. https://doi.org/10.1128/JVI.01705-14.

PMID
25142591
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Ritchie, Adam John, Fangping Cai, Nicola M. G. Smith, Sheri Chen, Hongshuo Song, Simon Brackenridge, Salim S. Abdool Karim, et al. “Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection..” Retrovirology 11 (September 12, 2014). https://doi.org/10.1186/s12977-014-0069-9.

PMID
25212771
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Pages