Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Ma, Ying-Wei, Shu-Bin Hao, Le-le Sun, Jing Li, Qiao Qiao, Feng Gao, Li Zhao, Xue-Jie Yu, Zhi-Yu Wang, and Hong-Ling Wen. “Construction and characterization of infectious cDNA clones of enterovirus 71 (EV71)..” Virol Sin 30, no. 4 (August 2015): 305–8. https://doi.org/10.1007/s12250-015-3614-3.

PMID
26271283
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Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission..” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.

PMID
26053661
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Demarco, Todd, Wes Rountree, Bhavna Hora, Yue Chen, Sarah Keinonen, Laura Racz, Lily Daniell, et al. “HIV-1 subtype C is significantly more infectious than other subtypes.” Journal of the International Aids Society 18 (July 1, 2015). https://doi.org/10.7448/IAS.18.5.20462.

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Fan, Peihu, Xiaojun Li, Shiyang Sun, Weiheng Su, Dong An, Feng Gao, Wei Kong, and Chunlai Jiang. “Identification of a common epitope between enterovirus 71 and human MED25 proteins which may explain virus-associated neurological disease..” Viruses 7, no. 4 (March 27, 2015): 1558–77. https://doi.org/10.3390/v7041558.

PMID
25826188
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Fan, Peihu, Xiaojun Li, Weiheng Su, Wei Kong, Xianggui Kong, Zhenxin Wang, Youchun Wang, Chunlai Jiang, and Feng Gao. “Enhanced Sensitivity for Detection of HIV-1 p24 Antigen by a Novel Nuclease-Linked Fluorescence Oligonucleotide Assay..” Plos One 10, no. 4 (2015). https://doi.org/10.1371/journal.pone.0125701.

PMID
25915630
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Liu, Donglai, Tao Zuo, Bhavna Hora, Hongshuo Song, Wei Kong, Xianghui Yu, Nilu Goonetilleke, et al. “Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation..” Retrovirology 11 (November 19, 2014). https://doi.org/10.1186/s12977-014-0101-0.

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25407514
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Hraber, Peter, Bette T. Korber, Alan S. Lapedes, Robert T. Bailer, Michael S. Seaman, Hongmei Gao, Kelli M. Greene, et al. “Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies..” J Virol 88, no. 21 (November 2014): 12623–43. https://doi.org/10.1128/JVI.01705-14.

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25142591
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Ritchie, Adam John, Fangping Cai, Nicola M. G. Smith, Sheri Chen, Hongshuo Song, Simon Brackenridge, Salim S. Abdool Karim, et al. “Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection..” Retrovirology 11 (September 12, 2014). https://doi.org/10.1186/s12977-014-0069-9.

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25212771
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Gao, Feng, Mattia Bonsignori, Hua-Xin Liao, Amit Kumar, Shi-Mao Xia, Xiaozhi Lu, Fangping Cai, et al. “Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies..” Cell 158, no. 3 (July 31, 2014): 481–91. https://doi.org/10.1016/j.cell.2014.06.022.

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25065977
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Fera, Daniela, Aaron G. Schmidt, Barton F. Haynes, Feng Gao, Hua-Xin Liao, Thomas B. Kepler, and Stephen C. Harrison. “Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains..” Proc Natl Acad Sci U S A 111, no. 28 (July 15, 2014): 10275–80. https://doi.org/10.1073/pnas.1409954111.

PMID
24982157
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