Feng Gao, MD

Professor of Medicine
Member of the Duke Human Vaccine Institute
Campus mail 244 Sands Bldg, Box 102359, Durham, NC 27710
Phone (919) 668-6433
Email address feng.gao@duke.edu

Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins,  biology, pathogenesis and drug resistance, and to design new AIDS vaccines.

Education and Training

  • M.D., Harbin Medical University (China), 1984

Publications

Sanchez, Ana M., C Todd DeMarco, Bhavna Hora, Sarah Keinonen, Yue Chen, Christie Brinkley, Mars Stone, et al. “Development of a contemporary globally diverse HIV viral panel by the EQAPOL program..” J Immunol Methods 409 (July 2014): 117–30. https://doi.org/10.1016/j.jim.2014.01.004.

PMID
24447533
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Haynes, Barton F., M Anthony Moody, Munir Alam, Mattia Bonsignori, Laurent Verkoczy, Guido Ferrari, Feng Gao, Georgia D. Tomaras, Hua-Xin Liao, and Garnett Kelsoe. “Progress in HIV-1 vaccine development..” J Allergy Clin Immunol 134, no. 1 (July 2014): 3–10. https://doi.org/10.1016/j.jaci.2014.04.025.

PMID
25117798
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Bonsignori, Mattia, Kevin Wiehe, Sebastian K. Grimm, Rebecca Lynch, Guang Yang, Daniel M. Kozink, Florence Perrin, et al. “An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1..” J Clin Invest 124, no. 4 (April 2014): 1835–43. https://doi.org/10.1172/JCI73441.

PMID
24614107
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Xiang, Yue, Wei Liu, Yue Chen, Chuntao Zhang, Weiheng Su, Yan Zhang, Jiaxi Sun, Feng Gao, and Chunlai Jiang. “The variable loop 3 in the envelope glycoprotein is critical for the atypical coreceptor usage of an HIV-1 strain..” Plos One 9, no. 6 (2014). https://doi.org/10.1371/journal.pone.0098058.

PMID
24897520
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Song, Hongshuo, Bhavna Hora, Tanmoy Bhattacharya, Nilu Goonetilleke, Michael K. P. Liu, Kevin Wiehe, Hui Li, et al. “Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus..” Plos One 9, no. 7 (2014). https://doi.org/10.1371/journal.pone.0102734.

PMID
25028937
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Liu, Jia, Hongshuo Song, Donglai Liu, Tao Zuo, Fengmin Lu, Hui Zhuang, and Feng Gao. “Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR..” Plos One 9, no. 9 (2014). https://doi.org/10.1371/journal.pone.0106658.

PMID
25211143
Full Text

Liu, D., T. Zuo, B. Hora, H. Song, W. Kong, X. Yu, N. Goonetilleke, et al. “Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation.” Retrovirology, 2014. https://doi.org/10.1186/s12977-014-0101-0.

Full Text

Fenton-May, Angharad E., Oliver Dibben, Tanja Emmerich, Haitao Ding, Katja Pfafferott, Marlen M. Aasa-Chapman, Pierre Pellegrino, et al. “Relative resistance of HIV-1 founder viruses to control by interferon-alpha..” Retrovirology 10 (December 3, 2013). https://doi.org/10.1186/1742-4690-10-146.

PMID
24299076
Full Text

Gao, F., M. Bonsignori, H. Liao, A. Kumar, S. Xia, F. Cai, X. Lu, et al. “Multiple Pathways of HIV-1 Autologous Neutralizing Antibodies Cooperate to Drive CD4 Binding Site Broadly Neutralizing Antibody Responses.” In Aids Research and Human Retroviruses, 29:A186–A186. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

Zhang, R., M. Moody, M. Alam, J. Yu, S. Santra, G. Kelsoe, S. Sekaran, et al. “Isolation of mAbs from Sorted Single B Cells by RT/PCR for Analysis of B Cell Responses to HIV-1 MPER Epitope in Vaccinated Rhesus Macaques.” In Aids Research and Human Retroviruses, 29:A30–A30. MARY ANN LIEBERT, INC, 2013.

Scholars@Duke

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