Gordon Ralph Corey, MD

Professor of Medicine
Gary Hock Professor in Global Health, in the School of Medicine
Vice-Chair for Education and Global Health in the Department of Medicine
Research Professor of Global Health
Professor of Pathology
Member in the Duke Clinical Research Institute
Campus mail 310 Trent Drive Room 235 Trent, Box 90519, Durham, NC 27708
Phone (919) 668-7174
Email address corey001@mc.duke.edu

My research is based at the Duke Clinical Research Institute, a large academic clinical research organization designed to conduct clinical trials from small local studies to worldwide trials. The focus of my research is bacterial infections: complicated skin and skin structure infections; postoperative wound infections; hospital-acquired and ventilator-associated pneumonia; bacteremia; and endocarditis. Many of these trials are conducted in concert with the pharmaceutical industry in order to register new antibiotics. In addition, as director of infectious diseases at the DCRI I oversee the work of the mycology group, and tuberculosis trials. This work also includes work supported by NIH grants including sepsis trials, the Staph Aureus and Staph Epi Bacteremia Groups, and the International Collaboration of Endocarditis. The team of investigators with whom I work is highly experienced, amazingly productive and wonderfully collegial.

As a result of my longstanding interest in tropical medicine and the generosity of my patients as well as the Hubert Family we have been able to establish the Hubert-Yeargan Center for Global Health. As a result we have developed a medical center-wide fellowship in Global Health. I am presently the Director of the Center and the Gary Hock Distinguished Professor of Global Health.

Education and Training

  • Fellowship, Infectious Diseases, Duke University School of Medicine, 1978 - 1980
  • Chief Resident, General Internal Medicine, Duke University School of Medicine, 1977 - 1978
  • Residency, General Internal Medicine, Duke University School of Medicine, 1975 - 1977
  • Internship, General Internal Medicine, Duke University School of Medicine, 1974 - 1975
  • M.D., Baylor University, 1973

Publications

Huang, DB, O'Riordan, W, Overcash, JS, Heller, B, Amin, F, File, TM, Wilcox, MH, Torres, A, Dryden, M, Holland, TL, McLeroth, P, Shukla, R, and Corey, GR. "A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim Vs Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens: REVIVE-1." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 66, no. 8 (April 2018): 1222-1229.

PMID
29281036
Full Text

Smart, JI, Corey, GR, Stryjewski, ME, Wang, W, and Barriere, SL. "Assessment of telavancin minimal inhibitory concentrations by revised broth microdilution method in phase 3 complicated skin and skin-structure infection clinical trial isolates." Diagnostic microbiology and infectious disease 87, no. 3 (March 2017): 268-271.

PMID
28038840
Full Text

Doernberg, SB, Lodise, TP, Thaden, JT, Munita, JM, Cosgrove, SE, Arias, CA, Boucher, HW, Corey, GR, Lowy, FD, Murray, B, Miller, LG, Holland, TL, and Gram-Positive Committee of the Antibacterial Resistance Leadership Group (ARLG), . "Gram-Positive Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 64, no. suppl_1 (March 2017): S24-S29. (Review)

PMID
28350900
Full Text

Lodise, TP, Redell, M, Armstrong, SO, Sulham, KA, and Corey, GR. "Efficacy and safety of oritavancin relative to vancomycin for patients with acute bacterial skin and skin structure infections (ABSSSIs) in the outpatient setting: Results from the solo clinical trials." Open Forum Infectious Diseases 4, no. 1 (January 1, 2017): 1-9.

Full Text

Corey, GR, Arhin, FF, Wikler, MA, Sahm, DF, Kreiswirth, BN, Mediavilla, JR, Good, S, Fiset, C, Jiang, H, Moeck, G, Kabler, H, Green, S, O'Riordan, W, SOLO I, and SOLO II Investigators, . "Pooled analysis of single-dose oritavancin in the treatment of acute bacterial skin and skin-structure infections caused by Gram-positive pathogens, including a large patient subset with methicillin-resistant Staphylococcus aureus." International Journal of Antimicrobial Agents 48, no. 5 (November 2016): 528-534.

PMID
27665522
Full Text

Sivak, JA, Vora, AN, Navar, AM, Schulte, PJ, Crowley, AL, Kisslo, J, Corey, GR, Liao, L, Wang, A, Velazquez, EJ, and Samad, Z. "An Approach to Improve the Negative Predictive Value and Clinical Utility of Transthoracic Echocardiography in Suspected Native Valve Infective Endocarditis." Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 29, no. 4 (April 2016): 315-322.

PMID
26850679
Full Text

Kauf, TL, McKinnon, P, Corey, GR, Bedolla, J, Riska, PF, Sims, M, Jauregui-Peredo, L, Friedman, B, Hoehns, JD, Mercier, R-C, Garcia-Diaz, J, Brenneman, SK, Ng, D, and Lodise, T. "An open-label, pragmatic, randomized controlled clinical trial to evaluate the comparative effectiveness of daptomycin versus vancomycin for the treatment of complicated skin and skin structure infection." BMC infectious diseases 15 (November 7, 2015): 503-.

PMID
26547411
Full Text

Pushkin, R, Barriere, SL, Wang, W, Corey, GR, and Stryjewski, ME. "Telavancin for Acute Bacterial Skin and Skin Structure Infections, a Post Hoc Analysis of the Phase 3 ATLAS Trials in Light of the 2013 FDA Guidance." Antimicrobial agents and chemotherapy 59, no. 10 (October 2015): 6170-6174.

PMID
26248356
Full Text

Lacy, MK, Stryjewski, ME, Wang, W, Hardin, TC, Nogid, B, Luke, DR, Shorr, AF, Corey, GR, and Barriere, SL. "Telavancin hospital-acquired pneumonia trials: impact of Gram-negative infections and inadequate Gram-negative coverage on clinical efficacy and all-cause mortality." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 61 Suppl 2 (September 2015): S87-S93.

PMID
26316562
Full Text

Corey, GR, and Stryjewski, ME. "Reply to Solnick." Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 61, no. 3 (August 2015): 485-486. (Letter)

PMID
25956892
Full Text

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