Guofang Zhang, PhD

Assistant Professor in Medicine
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 684-2262
Email address guofang.zhang@duke.edu

Education and Training

  • M.S., Vrije Universiteit Brussel (Belgium), 2004
  • Ph.D., Nanjing University (China), 2001

Publications

Wang, Y, Christopher, BA, Wilson, KA, Muoio, D, McGarrah, RW, Brunengraber, H, and Zhang, G-F. "Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine." American Journal of Physiology. Endocrinology and Metabolism 315, no. 4 (October 2018): E622-E633.

PMID
30016154
Full Text

Chen, Y, Berejnaia, O, Liu, J, Wang, S-P, Daurio, NA, Yin, W, Mayoral, R, Petrov, A, Kasumov, T, Zhang, G-F, Previs, SF, Kelley, DE, and McLaren, DG. "Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS." American Journal of Physiology. Endocrinology and Metabolism 315, no. 3 (September 2018): E416-E424.

PMID
29509438
Full Text

White, PJ, McGarrah, RW, Grimsrud, PA, Tso, S-C, Yang, W-H, Haldeman, JM, Grenier-Larouche, T, An, J, Lapworth, AL, Astapova, I, Hannou, SA, George, T, Arlotto, M, Olson, LB, Lai, M, Zhang, G-F, Ilkayeva, O, Herman, MA, Wynn, RM, Chuang, DT, and Newgard, CB. "The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase." Cell Metabolism 27, no. 6 (June 2018): 1281-1293.e7.

PMID
29779826
Full Text

Bu, P, Chen, K-Y, Xiang, K, Johnson, C, Crown, SB, Rakhilin, N, Ai, Y, Wang, L, Xi, R, Astapova, I, Han, Y, Li, J, Barth, BB, Lu, M, Gao, Z, Mines, R, Zhang, L, Herman, M, Hsu, D, Zhang, G-F, and Shen, X. "Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis." Cell Metabolism 27, no. 6 (June 2018): 1249-1262.e4.

PMID
29706565
Full Text

McGarrah, RW, Crown, SB, Zhang, G-F, Shah, SH, and Newgard, CB. "Cardiovascular Metabolomics." Circulation Research 122, no. 9 (April 2018): 1238-1258. (Review)

PMID
29700070
Full Text

Wilson, KA, Han, Y, Zhang, M, Hess, JP, Chapman, KA, Cline, GW, Tochtrop, GP, Brunengraber, H, and Zhang, G-F. "Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism." American Journal of Physiology. Endocrinology and Metabolism 313, no. 4 (October 2017): E413-E428.

PMID
28634175
Full Text

Wilson, K, Hess, J, Zhang, G, Brunengraber, H, and Tochtrop, G. "Metabolism of Beta-Alanine in Rat Liver: Degradation to Acetyl-CoA and Carboxylation to 2-(aminomethyl)-malonate." April 2017.

Scholars@Duke

Sanabria, JR, Kombu, RS, Zhang, G-F, Sandlers, Y, Ai, J, Ibarra, RA, Abbas, R, Goyal, K, and Brunengraber, H. "Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma." HPB : the official journal of the International Hepato Pancreato Biliary Association 18, no. 12 (December 2016): 979-990.

PMID
28340971
Full Text

Guzzo, MB, Nguyen, HT, Pham, TH, Wyszczelska-Rokiel, M, Jakubowski, H, Wolff, KA, Ogwang, S, Timpona, JL, Gogula, S, Jacobs, MR, Ruetz, M, Kräutler, B, Jacobsen, DW, Zhang, G-F, and Nguyen, L. "Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs." Plos Pathogens 12, no. 10 (October 19, 2016): e1005949-null.

PMID
27760199
Full Text

Li, L, Zhang, G-F, Lee, K, Lopez, R, Previs, SF, Willard, B, McCullough, A, and Kasumov, T. "A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis." Free radical biology & medicine 96 (July 2016): 13-21.

PMID
27036364
Full Text

Pages