Guofang Zhang, PhD

Assistant Professor in Medicine
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 668-2368
Email address guofang.zhang@duke.edu

Education and Training

  • M.S., Vrije Universiteit Brussel (Belgium), 2004
  • Ph.D., Nanjing University (China), 2001

Publications

Yu, Yilin, Hunter Newman, Leyao Shen, Deepika Sharma, Guoli Hu, Anthony J. Mirando, Hongyuan Zhang, et al. “Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells..” Cell Metab 29, no. 4 (April 2, 2019): 966-978.e4. https://doi.org/10.1016/j.cmet.2019.01.016.

PMID
30773468
Full Text

Bryant, Kirsten L., Clint A. Stalnecker, Daniel Zeitouni, Jennifer E. Klomp, Sen Peng, Andrey P. Tikunov, Venugopal Gunda, et al. “Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer..” Nat Med 25, no. 4 (April 2019): 628–40. https://doi.org/10.1038/s41591-019-0368-8.

PMID
30833752
Full Text

Wang, Yingxue, Bridgette A. Christopher, Kirkland A. Wilson, Deborah Muoio, Robert W. McGarrah, Henri Brunengraber, and Guo-Fang Zhang. “Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine..” Am J Physiol Endocrinol Metab 315, no. 4 (October 1, 2018): E622–33. https://doi.org/10.1152/ajpendo.00081.2018.

PMID
30016154
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Chen, Ying, Olga Berejnaia, Jinqi Liu, Sheng-Ping Wang, Natalie A. Daurio, Wu Yin, Rafael Mayoral, et al. “Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS..” Am J Physiol Endocrinol Metab 315, no. 3 (September 1, 2018): E416–24. https://doi.org/10.1152/ajpendo.00457.2017.

PMID
29509438
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Bu, Pengcheng, Kai-Yuan Chen, Kun Xiang, Christelle Johnson, Scott B. Crown, Nikolai Rakhilin, Yiwei Ai, et al. “Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis..” Cell Metab 27, no. 6 (June 5, 2018): 1249-1262.e4. https://doi.org/10.1016/j.cmet.2018.04.003.

PMID
29706565
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White, Phillip J., Robert W. McGarrah, Paul A. Grimsrud, Shih-Chia Tso, Wen-Hsuan Yang, Jonathan M. Haldeman, Thomas Grenier-Larouche, et al. “The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase..” Cell Metab 27, no. 6 (June 5, 2018): 1281-1293.e7. https://doi.org/10.1016/j.cmet.2018.04.015.

PMID
29779826
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Wilson, Kirkland A., Yong Han, Miaoqi Zhang, Jeremy P. Hess, Kimberly A. Chapman, Gary W. Cline, Gregory P. Tochtrop, Henri Brunengraber, and Guo-Fang Zhang. “Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism..” Am J Physiol Endocrinol Metab 313, no. 4 (October 1, 2017): E413–28. https://doi.org/10.1152/ajpendo.00105.2017.

PMID
28634175
Full Text

Wilson, Kirkland, Jeremy Hess, Guofang Zhang, Henri Brunengraber, and Gregory Tochtrop. “Metabolism of Beta-Alanine in Rat Liver: Degradation to Acetyl-CoA and Carboxylation to 2-(aminomethyl)-malonate.” In Faseb Journal, Vol. 31. FEDERATION AMER SOC EXP BIOL, 2017.

Scholars@Duke

Sanabria, Juan R., Rajan S. Kombu, Guo-Fang Zhang, Yana Sandlers, Jizhou Ai, Rafael A. Ibarra, Rime Abbas, Kush Goyal, and Henri Brunengraber. “Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma..” Hpb (Oxford) 18, no. 12 (December 2016): 979–90. https://doi.org/10.1016/j.hpb.2016.09.007.

PMID
28340971
Full Text

Pages