Guofang Zhang, PhD

Assistant Professor in Medicine
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Durham, NC 27701
Phone (919) 668-2368
Email address guofang.zhang@duke.edu

Education and Training

  • M.S., Vrije Universiteit Brussel (Belgium), 2004
  • Ph.D., Nanjing University (China), 2001

Publications

Yu, Y, Newman, H, Shen, L, Sharma, D, Hu, G, Mirando, AJ, Zhang, H, Knudsen, E, Zhang, G-F, Hilton, MJ, and Karner, CM. "Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells." Cell Metabolism 29, no. 4 (April 2019): 966-978.e4.

PMID
30773468
Full Text

Bryant, KL, Stalnecker, CA, Zeitouni, D, Klomp, JE, Peng, S, Tikunov, AP, Gunda, V, Pierobon, M, Waters, AM, George, SD, Tomar, G, Papke, B, Hobbs, GA, Yan, L, Hayes, TK, Diehl, JN, Goode, GD, Chaika, NV, Wang, Y, Zhang, G-F, Witkiewicz, AK, Knudsen, ES, Petricoin, EF, Singh, PK, Macdonald, JM, Tran, NL, Lyssiotis, CA, Ying, H, Kimmelman, AC, Cox, AD, and Der, CJ. "Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer." Nature Medicine 25, no. 4 (April 2019): 628-640.

PMID
30833752
Full Text

Wang, Y, Christopher, BA, Wilson, KA, Muoio, D, McGarrah, RW, Brunengraber, H, and Zhang, G-F. "Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine." American Journal of Physiology. Endocrinology and Metabolism 315, no. 4 (October 2018): E622-E633.

PMID
30016154
Full Text

Chen, Y, Berejnaia, O, Liu, J, Wang, S-P, Daurio, NA, Yin, W, Mayoral, R, Petrov, A, Kasumov, T, Zhang, G-F, Previs, SF, Kelley, DE, and McLaren, DG. "Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS." American Journal of Physiology. Endocrinology and Metabolism 315, no. 3 (September 2018): E416-E424.

PMID
29509438
Full Text

Bu, P, Chen, K-Y, Xiang, K, Johnson, C, Crown, SB, Rakhilin, N, Ai, Y, Wang, L, Xi, R, Astapova, I, Han, Y, Li, J, Barth, BB, Lu, M, Gao, Z, Mines, R, Zhang, L, Herman, M, Hsu, D, Zhang, G-F, and Shen, X. "Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis." Cell Metabolism 27, no. 6 (June 2018): 1249-1262.e4.

PMID
29706565
Full Text

White, PJ, McGarrah, RW, Grimsrud, PA, Tso, S-C, Yang, W-H, Haldeman, JM, Grenier-Larouche, T, An, J, Lapworth, AL, Astapova, I, Hannou, SA, George, T, Arlotto, M, Olson, LB, Lai, M, Zhang, G-F, Ilkayeva, O, Herman, MA, Wynn, RM, Chuang, DT, and Newgard, CB. "The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase." Cell Metabolism 27, no. 6 (June 2018): 1281-1293.e7.

PMID
29779826
Full Text

McGarrah, RW, Crown, SB, Zhang, G-F, Shah, SH, and Newgard, CB. "Cardiovascular Metabolomics." Circulation Research 122, no. 9 (April 2018): 1238-1258. (Review)

PMID
29700070
Full Text

Wilson, KA, Han, Y, Zhang, M, Hess, JP, Chapman, KA, Cline, GW, Tochtrop, GP, Brunengraber, H, and Zhang, G-F. "Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism." American Journal of Physiology. Endocrinology and Metabolism 313, no. 4 (October 2017): E413-E428.

PMID
28634175
Full Text

Wilson, K, Hess, J, Zhang, G, Brunengraber, H, and Tochtrop, G. "Metabolism of Beta-Alanine in Rat Liver: Degradation to Acetyl-CoA and Carboxylation to 2-(aminomethyl)-malonate." April 2017.

Scholars@Duke

Sanabria, JR, Kombu, RS, Zhang, G-F, Sandlers, Y, Ai, J, Ibarra, RA, Abbas, R, Goyal, K, and Brunengraber, H. "Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma." HPB : the official journal of the International Hepato Pancreato Biliary Association 18, no. 12 (December 2016): 979-990.

PMID
28340971
Full Text

Pages