Hans-Ewald Hohmeier, MD, PhD

Associate Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke Street, Durham, NC 27701
Phone (919) 479-2342
Email address hans.hohmeier@duke.edu

Education and Training

  • Postdoctoral Fellow, Biochemistry, UT Southwestern Medical School, 1995 - 1997
  • Postdoctoral Fellow, Immunology, UT Southwestern Medical School, 1991 - 1995
  • Ph.D., Georg August Universitat Gottingen (Germany), 1992
  • M.D., University of Hannover (Germany), 1986

Publications

Lemaire, K, Moura, RF, Granvik, M, Igoillo-Esteve, M, Hohmeier, HE, Hendrickx, N, Newgard, CB, Waelkens, E, Cnop, M, and Schuit, F. "Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis." Plos One 6, no. 4 (January 2011): e18517-null.

PMID
21494687
Full Text

Healy, JA, Nilsson, KR, Hohmeier, HE, Berglund, J, Davis, J, Hoffman, J, Kohler, M, Li, L-S, Berggren, P-O, Newgard, CB, and Bennett, V. "Cholinergic augmentation of insulin release requires ankyrin-B." Science Signaling 3, no. 113 (March 16, 2010): ra19-null.

PMID
20234002
Full Text

Malakauskas, SM, Kourany, WM, Zhang, XY, Lu, D, Stevens, RD, Koves, TR, Hohmeier, HE, Muoio, DM, Newgard, CB, and Le, TH. "Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha." Mol Endocrinol 23, no. 6 (June 2009): 881-892.

PMID
19246514
Full Text

Schnedl, WJ, Piswanger-Soelkner, C, Wallner, SJ, Reittner, P, Krause, R, Lipp, RW, and Hohmeier, HE. "Agenesis of the dorsal pancreas and associated diseases." Digestive Diseases and Sciences 54, no. 3 (2009): 481-487.

PMID
18618254
Full Text

Ronnebaum, SM, Jensen, MV, Hohmeier, HE, Burgess, SC, Zhou, Y-P, Qian, S, MacNeil, D, Howard, A, Thornberry, N, Ilkayeva, O, Lu, D, Sherry, AD, and Newgard, CB. "Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets." The Journal of Biological Chemistry 283, no. 43 (October 2008): 28909-28917.

PMID
18755687
Full Text

Schisler, JC, Fueger, PT, Babu, DA, Hohmeier, HE, Tessem, JS, Lu, D, Becker, TC, Naziruddin, B, Levy, M, Mirmira, RG, and Newgard, CB. "Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1." Molecular and Cellular Biology 28, no. 10 (May 2008): 3465-3476.

PMID
18347054
Full Text

Fueger, PT, Schisler, JC, Lu, D, Babu, DA, Mirmira, RG, Newgard, CB, and Hohmeier, HE. "Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function." Mol Endocrinol 22, no. 5 (May 2008): 1251-1259.

PMID
18258687
Full Text

Hardy, OT, Hohmeier, HE, Becker, TC, Manduchi, E, Doliba, NM, Gupta, RK, White, P, Stoeckert, CJ, Matschinsky, FM, Newgard, CB, and Kaestner, KH. "Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents." Molecular Endocrinology (Baltimore, Md.) 21, no. 3 (March 2007): 765-773.

PMID
17185391
Full Text

Chen, S, Ding, J-H, Bekeredjian, R, Yang, B-Z, Shohet, RV, Johnston, SA, Hohmeier, HE, Newgard, CB, and Grayburn, PA. "Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology." Proc Natl Acad Sci U S A 103, no. 22 (May 30, 2006): 8469-8474.

PMID
16709667
Full Text

Collier, JJ, Fueger, PT, Hohmeier, HE, and Newgard, CB. "Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines." Diabetes 55, no. 5 (May 2006): 1398-1406.

PMID
16644697
Full Text

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