Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center for Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Walston, Jeremy, Karen Bandeen-Roche, Brian Buta, Howard Bergman, Thomas M. Gill, John E. Morley, Linda P. Fried, et al. “Moving Frailty Toward Clinical Practice: NIA Intramural Frailty Science Symposium Summary..” J Am Geriatr Soc, May 2, 2019. https://doi.org/10.1111/jgs.15928.

PMID
31045254
Full Text

Kaufman, B. D., S. A. Hollander, Y. Zhang, S. Chen, D. Bernstein, D. N. Rosenthal, C. S. Almond, et al. “Compassionate deactivation of ventricular assist devices in children: A survey of pediatric ventricular assist device clinicians’ perspectives and practices.” Pediatric Transplantation 23, no. 3 (May 1, 2019). https://doi.org/10.1111/petr.13359.

Full Text

Hurria, Arti, Enrique Soto-Perez-de-Celis, Jacob B. Allred, Harvey Jay Cohen, Anait Arsenyan, Karla Ballman, Jennifer Le-Rademacher, et al. “Functional Decline and Resilience in Older Women Receiving Adjuvant Chemotherapy for Breast Cancer..” J Am Geriatr Soc 67, no. 5 (May 2019): 920–27. https://doi.org/10.1111/jgs.15493.

PMID
30146695
Full Text

Barginear, Myra, Amylou C. Dueck, Jacob B. Allred, Craig Bunnell, Harvey J. Cohen, Rachel A. Freedman, Arti Hurria, et al. “Age and the Risk of Paclitaxel-Induced Neuropathy in Women with Early-Stage Breast Cancer (Alliance A151411): Results from 1,881 Patients from Cancer and Leukemia Group B (CALGB) 40101..” Oncologist 24, no. 5 (May 2019): 617–23. https://doi.org/10.1634/theoncologist.2018-0298.

PMID
30409792
Full Text

Dao, Dyda, Tyler Zemla, Aminah Jatoi, Rachel A. Freedman, Arti Hurria, Hyman Muss, Harvey Jay Cohen, et al. “Older-Patient-Specific Cancer Trials: A Pooled Analysis of 2,277 Patients (A151715)..” Oncologist, April 11, 2019. https://doi.org/10.1634/theoncologist.2018-0803.

PMID
30975921
Full Text

Berger, Miles, Deborah Oyeyemi, Mobolaji O. Olurinde, Heather E. Whitson, Kent J. Weinhold, Marty G. Woldorff, Lewis A. Lipsitz, et al. “The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction..” J Am Geriatr Soc 67, no. 4 (April 2019): 794–98. https://doi.org/10.1111/jgs.15770.

PMID
30674067
Full Text

Deardorff, William James, Phillip L. Liu, Richard Sloane, Courtney Van Houtven, Carl F. Pieper, Susan Nicole Hastings, Harvey J. Cohen, and Heather E. Whitson. “Association of Sensory and Cognitive Impairment With Healthcare Utilization and Cost in Older Adults..” J Am Geriatr Soc, March 29, 2019. https://doi.org/10.1111/jgs.15891.

PMID
30924932
Full Text

Ambrosy, Andrew P., Jerry H. Gurwitz, Grace H. Tabada, Andrew Artz, Stanley Schrier, Sunil V. Rao, Huiman X. Barnhart, et al. “Incident Anemia in Older Adults with Heart Failure Rate, Etiology, and Association with Outcomes..” European Heart Journal. Quality of Care & Clinical Outcomes, March 7, 2019. https://doi.org/10.1093/ehjqcco/qcz010.

PMID
30847487
Full Text

Ganti, Apar Kishor, Xiaofei Wang, Thomas E. Stinchcombe, Yinpeng Wang, Jeffrey Bradley, Harvey J. Cohen, Karen Kelly, et al. “Clinical prognostic model for older patients with advanced non-small cell lung cancer..” J Geriatr Oncol, February 20, 2019. https://doi.org/10.1016/j.jgo.2019.02.007.

PMID
30797707
Full Text

Pages