Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Cohen, HJ. "Response by Dr. Cohen." Journal of the American Geriatrics Society 35, no. 5 (May 1987): 474-474.

Full Text

Becker, PM, Mcvey, LJ, Saltz, CC, Feussner, JR, and Cohen, HJ. "Hospital-Acquired Complications in a Randomized Controlled Clinical Trial of a Geriatric Consultation Team." JAMA: The Journal of the American Medical Association 257, no. 17 (May 1, 1987): 2313-2317.

Full Text

Cohen, HJ. "Doctor-patient relationships in new health care systems." N Engl J Med 316, no. 16 (April 16, 1987): 1031-. (Letter)

PMID
3561453
Full Text

Whitin, JC, Takahashi, K, and Cohen, HJ. "Activation of neutrophil superoxide production by concanavalin A can occur at low levels of intracellular ionized calcium." Blood 69, no. 3 (March 1987): 762-768.

PMID
3028535
Scholars@Duke

Cohen, HJ, Tape, EH, Novak, J, Chovaniec, ME, Liegey, P, and Whitin, JC. "The role of glutathione reductase in maintaining human granulocyte function and sensitivity to exogenous H2O2." Blood 69, no. 2 (February 1987): 493-500.

PMID
3801665
Scholars@Duke

Crawford, J, Eye-Boland, MK, and Cohen, HJ. "Clinical utility of erythrocyte sedimentation rate and plasma protein analysis in the elderly." Am J Med 82, no. 2 (February 1987): 239-246.

PMID
3812516
Scholars@Duke

Cohen, HJ, Bernstein, RJ, and Grufferman, S. "Role of immune stimulation in the etiology of multiple myeloma: a case control study." Am J Hematol 24, no. 2 (February 1987): 119-126.

PMID
3812465
Scholars@Duke

Neuss, MN, Feussner, JR, DeLong, ER, and Cohen, HJ. "A quantitative analysis of palliative care decisions in acute nonlymphocytic leukemia." J Am Geriatr Soc 35, no. 2 (February 1987): 125-131.

PMID
2433324
Scholars@Duke

Crawford, J, Eye, MK, and Cohen, HJ. "Evaluation of monoclonal gammopathies in the "well" elderly." Am J Med 82, no. 1 (January 1987): 39-45.

PMID
3492143
Scholars@Duke

Cohen, HJ, Cox, E, Manton, K, and Woodbury, M. "Malignant melanoma in the elderly." J Clin Oncol 5, no. 1 (January 1987): 100-106.

PMID
3806154
Full Text

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