Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Jatoi, A, Muss, H, Allred, JB, Cohen, HJ, Ballman, K, Hopkins, JO, Gajra, A, Lafky, J, Wolff, A, Kottschade, L, Gralow, J, and Hurria, A. "Social support and its implications in older, early-stage breast cancer patients in CALGB 49907 (Alliance A171301)." Psycho-oncology 25, no. 4 (April 2016): 441-446.

PMID
25994447
Full Text

Whitson, HE, Duan-Porter, W, Schmader, KE, Morey, MC, Cohen, HJ, and Colón-Emeric, CS. "Physical Resilience in Older Adults: Systematic Review and Development of an Emerging Construct." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 71, no. 4 (April 2016): 489-495. (Review)

PMID
26718984
Full Text

Cohen, HJ, Walston, JD, Rao, SV, Schrier, SL, Artz, A, and Partnership for Anemia: Clinical and Translational Trials in the Elderly Consortium, . "Renal Toxicity Associated with Salsalate in Elderly Adults with Anemia." Journal of the American Geriatrics Society 64, no. 4 (April 2016): 898-899. (Letter)

PMID
27100595
Full Text

Povsic, TJ, Sloane, R, Pieper, CF, Pearson, MP, Peterson, ED, Cohen, HJ, and Morey, MC. "Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 71, no. 3 (March 2016): 362-369.

PMID
26511012
Full Text

Lichtman, SM, Cirrincione, CT, Hurria, A, Jatoi, A, Theodoulou, M, Wolff, AC, Gralow, J, Morganstern, DE, Magrinat, G, Cohen, HJ, and Muss, HB. "Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 34, no. 7 (March 2016): 699-705.

PMID
26755510
Full Text

Koenig, HG, Nelson, B, Shaw, SF, Saxena, S, and Cohen, HJ. "Religious Involvement and Adaptation in Female Family Caregivers." Journal of the American Geriatrics Society 64, no. 3 (March 2016): 578-583.

PMID
27000331
Full Text

Peterson, MJ, Thompson, DK, Pieper, CF, Morey, MC, Kraus, VB, Kraus, WE, Sullivan, P, Fillenbaum, G, and Cohen, HJ. "A Novel Analytic Technique to Measure Associations Between Circulating Biomarkers and Physical Performance Across the Adult Life Span." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 71, no. 2 (February 2016): 196-202.

PMID
25745025
Full Text

Rao, AV, and Cohen, HJ. "Preface." Clinics in geriatric medicine 32, no. 1 (February 2016): xiii-xiv.

PMID
26614869
Full Text

Koenig, HG, Pearce, M, Nelson, B, Shaw, S, Robins, C, Daher, N, Cohen, HJ, and King, MB. "Effects of religious vs. standard cognitive behavioral therapy on therapeutic alliance: A randomized clinical trial." Psychotherapy research : journal of the Society for Psychotherapy Research 26, no. 3 (January 2016): 365-376.

PMID
25669236
Full Text

Koenig, HG, Nelson, B, Shaw, SF, Saxena, S, and Cohen, HJ. "Religious Involvement and Telomere Length in Women Family Caregivers." The Journal of nervous and mental disease 204, no. 1 (January 2016): 36-42.

PMID
26669979
Full Text

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