James Abbruzzese, MD

Professor of Medicine
D. C. I. Distinguished Professor of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., The University of Chicago, 1978

Publications

Dong, Xiaoqun, Yanan Li, Ping Chang, Hongwei Tang, Kenneth R. Hess, James L. Abbruzzese, and Donghui Li. “Glucose metabolism gene variants modulate the risk of pancreatic cancer.” Cancer Prev Res (Phila) 4, no. 5 (May 2011): 758–66. https://doi.org/10.1158/1940-6207.CAPR-10-0247.

PMID
21411499
Full Text

Tang, Hongwei, Xiaoqun Dong, Manal Hassan, James L. Abbruzzese, and Donghui Li. “Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer.” Cancer Epidemiol Biomarkers Prev 20, no. 5 (May 2011): 779–92. https://doi.org/10.1158/1055-9965.EPI-10-0845.

PMID
21357378
Full Text

Bernatchez, Chantale, Kuichin Zhu, Yufeng Li, Helen Andersson, Constantin Ionnides, Marcelo Fernandez-Vina, Pedro Cano, et al. “Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.” Vaccine 29, no. 16 (April 5, 2011): 3021–30. https://doi.org/10.1016/j.vaccine.2011.01.115.

PMID
21320548
Full Text

Fogelman, David R., Robert A. Wolff, Scott Kopetz, Milind Javle, Charles Bradley, Isabel Mok, Fernando Cabanillas, and James L. Abbruzzese. “Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer.” Anticancer Res 31, no. 4 (April 2011): 1417–20.

PMID
21508395
Scholars@Duke

Ramanathan, Ramesh K., James Abbruzzese, Tomislav Dragovich, Lynn Kirkpatrick, Jose M. Guillen, Amanda F. Baker, Linda A. Pestano, Sylvan Green, and Daniel D. Von Hoff. “A randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination.” Cancer Chemother Pharmacol 67, no. 3 (March 2011): 503–9. https://doi.org/10.1007/s00280-010-1343-8.

PMID
20461382
Full Text

Song, Xianzhou, Hua Wang, Craig D. Logsdon, Asif Rashid, Jason B. Fleming, James L. Abbruzzese, Henry F. Gomez, Douglas B. Evans, and Huamin Wang. “Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma.” Cancer 117, no. 4 (February 15, 2011): 734–43. https://doi.org/10.1002/cncr.25483.

PMID
20922806
Full Text

Tanaka, Motofumi, Taro Okazaki, Hideo Suzuki, James L. Abbruzzese, and Donghui Li. “Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.” Cancer 117, no. 4 (February 15, 2011): 744–51. https://doi.org/10.1002/cncr.25510.

PMID
20922799
Full Text

Dong, Xiaoqun, Hongwei Tang, Kenneth R. Hess, James L. Abbruzzese, and Donghui Li. “Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer.” Cancer 117, no. 3 (February 1, 2011): 480–91. https://doi.org/10.1002/cncr.25612.

PMID
20845477
Full Text

Basha, Riyaz, Cheryl H. Baker, Umesh T. Sankpal, Sarfraz Ahmad, Stephen Safe, James L. Abbruzzese, and Maen Abdelrahim. “Therapeutic applications of NSAIDS in cancer: special emphasis on tolfenamic acid.” Front Biosci (Schol Ed) 3, no. 2 (January 1, 2011): 797–805. https://doi.org/10.2741/s188.

PMID
21196413
Full Text

Pages