James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Bouvet, M., R. J. Bold, J. Lee, D. B. Evans, J. L. Abbruzzese, P. J. Chiao, D. J. McConkey, et al. “Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments].” Ann Surg Oncol 5, no. 8 (December 1998): 681–88. https://doi.org/10.1007/bf02303477.

PMID
9869513
Full Text

Breslin, T. M., N. A. Janjan, J. E. Lee, P. W. Pisters, R. A. Wolff, J. L. Abbruzzese, and D. B. Evans. “Neoadjuvant chemoradiation for adenocarcinoma of the pancreas.” In Front Biosci, 3:E193–203, 1998. https://doi.org/10.2741/a377.

PMID
9792895
Full Text

NCCN practice guidelines for occult primary tumors. National Comprehensive Cancer Network.” In Oncology (Williston Park), 12:226–309, 1998.

PMID
10028513
Scholars@Duke

Touroutoglou, N., D. Gravel, M. N. Raber, W. Plunkett, and J. L. Abbruzzese. “Clinical results of a pharmacodynamically-based strategy for higher dosing of gemcitabine in patients with solid tumors.” Ann Oncol 9, no. 9 (September 1998): 1003–8. https://doi.org/10.1023/A:1008487932384.

PMID
9818075
Full Text

Robinson, E. K., A. M. Grau, D. B. Evans, C. M. Smid, P. J. Chiao, J. L. Abbruzzese, and E. A. Grimm. “Cell cycle regulation of human pancreatic cancer by tamoxifen.” Ann Surg Oncol 5, no. 4 (June 1998): 342–49. https://doi.org/10.1007/bf02303498.

PMID
9641456
Full Text

Miller, A. R., P. W. Pisters, J. E. Lee, N. A. Janjan, J. L. Abbruzzese, and D. B. Evans. “Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas.” Hepatogastroenterology 45, no. 21 (May 1998): 624–33.

PMID
9684107
Scholars@Duke

Lenzi, R., E. E. Kim, M. N. Raber, and J. L. Abbruzzese. “Detection of primary breast cancer presenting as metastatic carcinoma of unknown primary origin by 111In-pentetreotide scan.” Ann Oncol 9, no. 2 (February 1998): 213–16. https://doi.org/10.1023/a:1008265113591.

PMID
9553668
Full Text

Garteiz, D. A., T. Madden, D. E. Beck, W. R. Huie, K. T. McManus, J. L. Abbruzzese, W. Chen, and R. A. Newman. “Quantitation of dolastatin-10 using HPLC/electrospray ionization mass spectrometry: application in a phase I clinical trial.” Cancer Chemother Pharmacol 41, no. 4 (1998): 299–306. https://doi.org/10.1007/s002800050743.

PMID
9488599
Full Text

Evans, D. B., P. W. Pisters, J. E. Lee, R. J. Bold, C. Charnsangavej, N. A. Janjan, R. A. Wolff, and J. L. Abbruzzese. “Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas.” J Hepatobiliary Pancreat Surg 5, no. 3 (1998): 242–50. https://doi.org/10.1007/s005340050041.

PMID
9880770
Full Text

Pages