James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., The University of Chicago, 1978

Publications

Jones, D. V., J. A. Ajani, R. Blackburn, K. Daugherty, B. Levin, Y. Z. Patt, and J. L. Abbruzzese. “Phase II study of didemnin B in advanced colorectal cancer.” Invest New Drugs 10, no. 3 (August 1992): 211–13. https://doi.org/10.1007/BF00877248.

PMID
1428730
Full Text

Anzai, H., P. Frost, and J. L. Abbruzzese. “Synergistic cytotoxicity with 2'-deoxy-5-azacytidine and topotecan in vitro and in vivo.” Cancer Res 52, no. 8 (April 15, 1992): 2180–85.

PMID
1373105
Scholars@Duke

Hubbard, K. P., K. Daugherty, J. A. Ajani, R. Pazdur, B. Levin, and J. L. Abbruzzese. “Phase II trial of fazarabine in advanced colorectal carcinoma.” Invest New Drugs 10, no. 1 (April 1992): 39–42. https://doi.org/10.1007/BF01275479.

PMID
1376722
Full Text

Raber, M. N., J. L. Abbruzzese, and P. Frost. “Unknown primary tumors.” Curr Opin Oncol 4, no. 1 (February 1992): 3–9.

PMID
1591292
Scholars@Duke

Abbruzzese, J. L., and P. Frost. “Studies on the mechanism of the synergistic interaction between 2'-deoxy-5-azacytidine and cisplatin.” Cancer Chemother Pharmacol 30, no. 1 (1992): 31–36. https://doi.org/10.1007/BF00686482.

PMID
1375133
Full Text

Abbruzzese, J. L., C. F. Gholson, K. Daugherty, E. Larson, R. DuBrow, R. Berlin, and B. Levin. “A pilot clinical trial of the cholecystokinin receptor antagonist MK-329 in patients with advanced pancreatic cancer.” Pancreas 7, no. 2 (1992): 165–71. https://doi.org/10.1097/00006676-199203000-00006.

PMID
1553366
Full Text

Ajani, J. A., R. Pazdur, R. J. Winn, J. L. Abbruzzese, B. Levin, R. Belt, J. Young, Y. Z. Patt, and I. H. Krakoff. “Phase II study of intravenous 6-thioguanine in patients with advanced carcinoma of the pancreas.” Invest New Drugs 9, no. 4 (November 1991): 369–71. https://doi.org/10.1007/BF00183584.

PMID
1804816
Full Text

Linke, K., R. Pazdur, J. L. Abbruzzese, J. A. Ajani, R. Winn, J. E. Bradof, K. Daugherty, and B. Levin. “Phase II study of amonafide in advanced pancreatic adenocarcinoma.” Invest New Drugs 9, no. 4 (November 1991): 353–56. https://doi.org/10.1007/BF00183580.

PMID
1804812
Full Text

Pages