James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Raber, M. N., J. L. Abbruzzese, and P. Frost. “Unknown primary tumors..” Curr Opin Oncol 4, no. 1 (February 1992): 3–9.

PMID
1591292
Scholars@Duke

Abbruzzese, J. L., and P. Frost. “Studies on the mechanism of the synergistic interaction between 2'-deoxy-5-azacytidine and cisplatin..” Cancer Chemother Pharmacol 30, no. 1 (1992): 31–36. https://doi.org/10.1007/bf00686482.

PMID
1375133
Full Text

Abbruzzese, J. L., C. F. Gholson, K. Daugherty, E. Larson, R. DuBrow, R. Berlin, and B. Levin. “A pilot clinical trial of the cholecystokinin receptor antagonist MK-329 in patients with advanced pancreatic cancer..” Pancreas 7, no. 2 (1992): 165–71. https://doi.org/10.1097/00006676-199203000-00006.

PMID
1553366
Full Text

Ajani, J. A., R. Pazdur, R. J. Winn, J. L. Abbruzzese, B. Levin, R. Belt, J. Young, Y. Z. Patt, and I. H. Krakoff. “Phase II study of intravenous 6-thioguanine in patients with advanced carcinoma of the pancreas..” Invest New Drugs 9, no. 4 (November 1991): 369–71. https://doi.org/10.1007/bf00183584.

PMID
1804816
Full Text

Linke, K., R. Pazdur, J. L. Abbruzzese, J. A. Ajani, R. Winn, J. E. Bradof, K. Daugherty, and B. Levin. “Phase II study of amonafide in advanced pancreatic adenocarcinoma..” Invest New Drugs 9, no. 4 (November 1991): 353–56. https://doi.org/10.1007/bf00183580.

PMID
1804812
Full Text

Lee, N. K., R. M. Byers, J. L. Abbruzzese, and P. Wolf. “Metastatic adenocarcinoma to the neck from an unknown primary source..” Am J Surg 162, no. 4 (October 1991): 306–9. https://doi.org/10.1016/0002-9610(91)90137-3.

PMID
1951879
Full Text

Ajani, J. A., R. Pazdur, R. J. Winn, J. L. Abbruzzese, B. Levin, C. Wiseman, M. A. Lenado-Lee, Y. Z. Patt, and I. H. Krakoff. “Phase II study of intravenous 6-thioguanine in patients with advanced gastric carcinoma..” Invest New Drugs 9, no. 3 (August 1991): 257–59. https://doi.org/10.1007/bf00176979.

PMID
1783525
Full Text

Raber, M. N., J. Faintuch, J. L. Abbruzzese, C. Sumrall, and P. Frost. “Continuous infusion 5-fluorouracil, etoposide and cis-diamminedichloroplatinum in patients with metastatic carcinoma of unknown primary origin..” Ann Oncol 2, no. 7 (July 1991): 519–20. https://doi.org/10.1093/oxfordjournals.annonc.a058007.

PMID
1911461
Full Text

Abbruzzese, J. L., R. Grunewald, E. A. Weeks, D. Gravel, T. Adams, B. Nowak, S. Mineishi, P. Tarassoff, W. Satterlee, and M. N. Raber. “A phase I clinical, plasma, and cellular pharmacology study of gemcitabine..” J Clin Oncol 9, no. 3 (March 1991): 491–98. https://doi.org/10.1200/JCO.1991.9.3.491.

PMID
1999720
Full Text

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