Cardiology

James William Wisler, MD

Medical Instructor in the Department of Medicine
Campus mail 448 Jones Bldg, Durham, NC 27710
Phone (919) 684-4906
Email address jim.wisler@duke.edu

Education and Training

  • Cardiovascular Diseases Fellowship, Medicine, Duke University School of Medicine, 2011 - 2016
  • Internal Medicine Residency, Medicine, Duke University School of Medicine, 2009 - 2011
  • M.D., Ohio State University College of Medicine, 2009

Grants

Publications

Kim, Jihee, Chad A. Grotegut, James W. Wisler, Tianyu Li, Lan Mao, Minyong Chen, Wei Chen, Paul B. Rosenberg, Howard A. Rockman, and Robert J. Lefkowitz. “β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility..” Skelet Muscle 8, no. 1 (December 27, 2018). https://doi.org/10.1186/s13395-018-0184-8.

PMID
30591079
Full Text

Kochar, Ajar, Jennifer Rymer, Zainab Samad, and Zainab Duke Cardiovascular Education Group. “Disrupting Fellow Education Through Group Texting: WhatsApp in Fellow Education?.” J Am Coll Cardiol 72, no. 25 (December 25, 2018): 3366–69. https://doi.org/10.1016/j.jacc.2018.11.007.

PMID
30573034
Full Text

Rein, Lindsay Am, James W. Wisler, Jihee Kim, Barbara Theriot, LiYin Huang, Trevor Price, Haeyoon Yang, et al. “β-Arrestin2 mediates progression of murine primary myelofibrosis..” Jci Insight 2, no. 24 (December 21, 2017). https://doi.org/10.1172/jci.insight.98094.

PMID
29263312
Full Text

Kahsai, Alem W., James W. Wisler, Jungmin Lee, Seungkirl Ahn, Thomas J. Cahill Iii, S Moses Dennison, Dean P. Staus, et al. “Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor..” Nat Chem Biol 12, no. 9 (September 2016): 709–16. https://doi.org/10.1038/nchembio.2126.

PMID
27398998
Full Text

Rein, Lindsay A. M., James W. Wisler, Barbara S. Theriot, Li-Yin Huang, Richard T. Premont, and Robert J. Lefkowitz. “beta-arrestin2 Is Necessary for Development of MPLW515L Mutant Primary Myelofibrosis.” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.

Scholars@Duke

Wisler, James W., Emily M. Harris, Michael Raisch, Lan Mao, Jihee Kim, Howard A. Rockman, and Robert J. Lefkowitz. “The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome..” Am J Physiol Heart Circ Physiol 309, no. 9 (November 2015): H1516–27. https://doi.org/10.1152/ajpheart.00291.2015.

PMID
26371162
Full Text

Wisler, James, Emily Harris, Michael Raisch, Lan Mao, Jihee Kim, Howard Rockman, and Robert Lefkowitz. “NON-CANONICAL ANGIOTENSIN II TYPE 1A RECEPTOR-MEDIATED, BETA-ARRESTIN2-DEPENDENT SIGNALING CONTRIBUTES TO THORACIC AORTIC ANEURYSM FORMATION IN A MURINE MODEL OF MARFAN SYNDROME.” In Journal of the American College of Cardiology, 63:A2148–A2148. Elsevier BV, 2014. https://doi.org/10.1016/s0735-1097(14)62151-3.

Full Text

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