Joe Brice Weinberg, MD

Professor of Medicine
Associate Professor of Obstetrics and Gynecology
Professor of Immunology
Affiliate, Duke Global Health Institute
Member of the Duke Cancer Institute
Campus mail Duke Box 3396, Durham, NC 27708
Phone (919) 286-6833
Email address weinb001@duke.edu

Dr. Weinberg is a board-certified hematologist and medical oncologist who serves as Professor of Medicine and Immunology and Associate Professor of Obstetrics and Gynecology at the Duke University Medical Center, and staff physician in hematology-oncology at the Durham V.A. Medical Center. His clinical interests are in hematology and oncology, and his research focuses on blood cells, nitric oxide (NO), and leukemia. The work includes studies of resistance to infection, pathways of inflammation, and regulation of normal and leukemic cell life and death. His current work includes studies of leukemia (primarily chronic lymphocytic leukemia); the roles of NO and arginine in the resistance to malaria; and the interactions of NO, prostaglandins, and mechanical force in inflammation and arthritis.

Education and Training

  • Fellowship, Hematology Oncology, University of Utah School of Medicine, 1973 - 1976
  • Internship & Residency, University of Arkansas at Little Rock, 1969 - 1971
  • M.D., University of Arkansas at Little Rock, 1969
  • B.S., University of Arkansas, Fayetteville, 1966

Publications

Rivera, Jessica de, Matthew Grigg, Dongying Ma, Yu Yang, Bridget Barber, Timothy William, Kim Piera, et al. “DO ALPHA GLOBIN GENE VARIANTS AFFECT ENDOTHELIAL FUNCTION IN PATIENTS WITH SEVERE MALARIA?” In American Journal of Tropical Medicine and Hygiene, 99:532–532. AMER SOC TROP MED & HYGIENE, 2018.

Scholars@Duke

Brander, Danielle, J Brice Weinberg, Daphne Friedman, Tiffany Stewart, and David Rizzieri. “Phase I trial of lenalidomide in combination with plerixafor for relapsed/refractory chronic lymphocytic leukemia (CLL): follow-up and correlative analysis.” In Leukemia & Lymphoma, 58:35–37. TAYLOR & FRANCIS LTD, 2017.

Scholars@Duke

Song, Julia, Michael Song, Vu Phan, J Brice Weinberg, Trisa maria Palmares, Sam Lee, and Laurie Mortara. “Ruxolitinib in treatment of refractory hypereosinophilic syndrome.” In Journal of Clinical Oncology, 35:73–73. American Society of Clinical Oncology (ASCO), 2017. https://doi.org/10.1200/jco.2017.35.7_suppl.73.

Full Text

Rubach, Matthew P., Jackson Mukemba, Salvatore Florence, Nicholas M. Anstey, Tsin W. Yeo, Esther D. Mwaikambo, J Brice Weinberg, and Donald L. Granger. “SEVERE DEFICIENCIES OF AMINO ACID PRECURSORS FOR L-ARGININE DE NOVO BIOSYNTHESIS IN PEDIATRIC FALCIPARUM MALARIA: IMPLICATIONS FOR NITRIC OXIDE INSUFFICIENCY.” In American Journal of Tropical Medicine and Hygiene, 97:478–478. AMER SOC TROP MED & HYGIENE, 2017.

Scholars@Duke

Winkler, Mark T., Ryan T. Bushey, Elizabeth B. Gottlin, Michael J. Campa, Eross S. Guadalupe, Alicia D. Volkheimer, J Brice Weinberg, and Edward F. Patz. “Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody.” Plos One 12, no. 6 (2017): e0179841. https://doi.org/10.1371/journal.pone.0179841.

PMID
28658265
Full Text

Yeo, Tsin W., Salvatore M. Florence, Ayam R. Kalingonji, Youwei Chen, Donald L. Granger, Nicholas M. Anstey, Esther D. Mwaikambo, and J Brice Weinberg. “Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria.” Open Forum Infect Dis 4, no. 2 (2017): ofx079. https://doi.org/10.1093/ofid/ofx079.

PMID
28852670
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Lee, Seung, Coby Palmares, Niko Koutsoukos, J Brice Weinberg, Trisa Palmares, Alice Song, Harold Song, et al. “Ruxolitinib Used to Treat Hypereosinophilic Syndrome.” In Blood, 128:5500–5500. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.5500.5500.

Full Text

Davis, Carter Thomas, Arati V. Rao, Eross Guadalupe, Dale J. Christensen, and J Brice Weinberg. “Fingolimod Is Cytotoxic in Acute Myeloid Leukemia Independent of Additional Chemotherapeutic Agents.” In Blood, 128:5126–5126. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.5126.5126.

Full Text

Barber, Bridget E., Timothy William, Matthew J. Grigg, Kim A. Piera, Youwei Chen, Hao Wang, J Brice Weinberg, Tsin W. Yeo, and Nicholas M. Anstey. “Nitric Oxide-Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease.” J Infect Dis 214, no. 10 (November 15, 2016): 1557–64. https://doi.org/10.1093/infdis/jiw427.

PMID
27630198
Full Text

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