John J. Strouse, MD, PhD

Associate Professor of Medicine
Associate Professor in the Department of Pediatrics
Email address john.strouse@duke.edu

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

 

Education and Training

  • Fellow in Pediatric Hematology, Nci, National Institutes of Health, 2001 - 2004
  • Fellow in Pediatric Hematology/Oncology, Johns Hopkins University, 2001 - 2004
  • Fellow in Hematology, Nhlbi, National Institutes of Health, 2000 - 2004
  • Combined Internal Medicine/Pediatrics Residency, University of Rochester, 1996 - 2000
  • Ph.D., Johns Hopkins University, 2009
  • M.D., Johns Hopkins University School of Medicine, 1996

Publications

Li, Wenbo, Xiang Xu, Peiying Liu, John J. Strouse, James F. Casella, Hanzhang Lu, Peter C. M. van Zijl, and Qin Qin. “Quantification of whole-brain oxygenation extraction fraction and cerebral metabolic rate of oxygen consumption in adults with sickle cell anemia using individual T2 -based oxygenation calibrations..” Magn Reson Med, September 4, 2019. https://doi.org/10.1002/mrm.27972.

PMID
31483528
Full Text

Darbari, Isha, Emily Jacobs, Olivia Gordon, Diane Weiss, Kim Winship, James F. Casella, John J. Strouse, and Clifford M. Takemoto. “Correlates of successful transition in young adults with sickle cell disease..” Pediatr Blood Cancer, August 20, 2019. https://doi.org/10.1002/pbc.27939.

PMID
31429531
Full Text

Oyedeji, Charity, John Joseph Strouse, Regina D. Crawford, Melanie E. Garrett, Allison E. Ashley-Koch, and Marilyn J. Telen. “A multi-institutional comparison of younger and older adults with sickle cell disease..” Am J Hematol 94, no. 4 (April 2019): E115–17. https://doi.org/10.1002/ajh.25405.

PMID
30663090
Full Text

Casella, James F., Robert J. Adams, Donald J. Brambilla, John J. Strouse, Pia Maier, Rachel Dlugash, Radhika Avadhani, et al. “Developing a risk-based composite neurologic outcome for a trial of hydroxyurea in young children with sickle cell disease..” Clin Trials 16, no. 1 (February 2019): 20–31. https://doi.org/10.1177/1740774518807160.

PMID
30426764
Full Text

Farooq, Faheem, and John J. Strouse. “Disparities in Foundation and Federal Support and Development of New Therapeutics for Sickle Cell Disease and Cystic Fibrosis.” In Blood, Vol. 132. AMER SOC HEMATOLOGY, 2018. https://doi.org/10.1182/blood-2018-99-115609.

Full Text

Sadreameli, Christy, Benjamin Kopp, Susan E. Creary, Emily Jacobs, John J. Strouse, Sharon A. McGrath-Morrow, James F. Casella, and Elizabeth C. Matsui. “Allergic Sensitization Is Associated with Decreased Risk of ED Visits and Hospitalizations for Pain in Sickle Cell Disease.” In Blood, Vol. 132. AMER SOC HEMATOLOGY, 2018. https://doi.org/10.1182/blood-2018-99-119743.

Full Text

Kelly, Geoffrey S., Rosalyn W. Stewart, John J. Strouse, and Jennifer F. Anders. “Intranasal fentanyl improves time to analgesic delivery in sickle cell pain crises..” Am J Emerg Med 36, no. 7 (July 2018): 1305–7. https://doi.org/10.1016/j.ajem.2017.11.015.

PMID
29128141
Full Text

Sullivan, Keith M., Mitchell Horwitz, Ifeyinwa Osunkwo, Nirmish Shah, and John J. Strouse. “Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease..” Biol Blood Marrow Transplant 24, no. 5 (May 2018): 883–84. https://doi.org/10.1016/j.bbmt.2018.04.001.

PMID
29649619
Full Text

Bodinayake, Champica K., L Gayani Tillekeratne, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikara Arachchi, John J. Strouse, October M. Sessions, et al. “Evaluation of the WHO 2009 classification for diagnosis of acute dengue in a large cohort of adults and children in Sri Lanka during a dengue-1 epidemic..” Plos Negl Trop Dis 12, no. 2 (February 2018). https://doi.org/10.1371/journal.pntd.0006258.

PMID
29425194
Full Text

Choudhury, Natasha A., Michael R. DeBaun, Mark Rodeghier, Allison A. King, John J. Strouse, and Robert C. McKinstry. “Silent cerebral infarct definitions and full-scale IQ loss in children with sickle cell anemia..” Neurology 90, no. 3 (January 16, 2018): e239–46. https://doi.org/10.1212/WNL.0000000000004832.

PMID
29263226
Full Text

Pages