John J. Strouse, MD, PhD

Associate Professor of Medicine
Associate Professor in the Department of Pediatrics
Email address john.strouse@duke.edu

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

 

Education and Training

  • Fellow in Pediatric Hematology, Nci, National Institutes of Health, 2001 - 2004
  • Fellow in Pediatric Hematology/Oncology, Johns Hopkins University, 2001 - 2004
  • Fellow in Hematology, Nhlbi, National Institutes of Health, 2000 - 2004
  • Combined Internal Medicine/Pediatrics Residency, University of Rochester, 1996 - 2000
  • Ph.D., Johns Hopkins University, 2009
  • M.D., Johns Hopkins University School of Medicine, 1996

Publications

Oyedeji, C, Strouse, JJ, Crawford, RD, Garrett, ME, Ashley-Koch, AE, and Telen, MJ. "A multi-institutional comparison of younger and older adults with sickle cell disease." American Journal of Hematology 94, no. 4 (April 2019): E115-E117. (Letter)

PMID
30663090
Full Text

Casella, JF, Adams, RJ, Brambilla, DJ, Strouse, JJ, Maier, P, Dlugash, R, Avadhani, R, Vermillion, K, Tonascia, J, Voeks, JH, Hanley, DF, Thompson, RE, and Lehmann, HP. "Developing a risk-based composite neurologic outcome for a trial of hydroxyurea in young children with sickle cell disease." Clinical Trials (London, England) 16, no. 1 (February 2019): 20-31.

PMID
30426764
Full Text

Farooq, F, and Strouse, JJ. "Disparities in Foundation and Federal Support and Development of New Therapeutics for Sickle Cell Disease and Cystic Fibrosis." 60th Annual Meeting of the American-Society-of-Hematology (ASH). San Diego, CA. December 1, 2018 - December 4, 2018.: AMER SOC HEMATOLOGY, November 29, 2018.

Full Text

Sadreameli, C, Kopp, B, Creary, SE, Jacobs, E, Strouse, JJ, McGrath-Morrow, SA, Casella, JF, and Matsui, EC. "Allergic Sensitization Is Associated with Decreased Risk of ED Visits and Hospitalizations for Pain in Sickle Cell Disease." 60th Annual Meeting of the American-Society-of-Hematology (ASH). San Diego, CA. December 1, 2018 - December 4, 2018.: AMER SOC HEMATOLOGY, November 29, 2018.

Full Text

Kelly, GS, Stewart, RW, Strouse, JJ, and Anders, JF. "Intranasal fentanyl improves time to analgesic delivery in sickle cell pain crises." The American Journal of Emergency Medicine 36, no. 7 (July 2018): 1305-1307. (Letter)

PMID
29128141
Full Text

Sullivan, KM, Horwitz, M, Osunkwo, I, Shah, N, and Strouse, JJ. "Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease." Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 5 (May 2018): 883-884.

PMID
29649619
Full Text

Bodinayake, CK, Tillekeratne, LG, Nagahawatte, A, Devasiri, V, Kodikara Arachchi, W, Strouse, JJ, Sessions, OM, Kurukulasooriya, R, Uehara, A, Howe, S, Ong, XM, Tan, S, Chow, A, Tummalapalli, P, De Silva, AD, Østbye, T, Woods, CW, Gubler, DJ, and Reller, ME. "Evaluation of the WHO 2009 classification for diagnosis of acute dengue in a large cohort of adults and children in Sri Lanka during a dengue-1 epidemic." Plos Neglected Tropical Diseases 12, no. 2 (February 9, 2018): e0006258-null.

PMID
29425194
Full Text

Xu, F, Li, W, Liu, P, Hua, J, Strouse, JJ, Pekar, JJ, Lu, H, van Zijl, PCM, and Qin, Q. "Accounting for the role of hematocrit in between-subject variations of MRI-derived baseline cerebral hemodynamic parameters and functional BOLD responses." Human brain mapping 39, no. 1 (January 2018): 344-353.

PMID
29024300
Full Text

Choudhury, NA, DeBaun, MR, Rodeghier, M, King, AA, Strouse, JJ, and McKinstry, RC. "Silent cerebral infarct definitions and full-scale IQ loss in children with sickle cell anemia." Neurology 90, no. 3 (January 2018): e239-e246.

PMID
29263226
Full Text

Sadreameli, SC, Alade, RO, Mogayzel, PJ, McGrath-Morrow, S, and Strouse, JJ. "Asthma Screening in Pediatric Sickle Cell Disease: A Clinic-Based Program Using Questionnaires and Spirometry." Pediatric Allergy, Immunology, and Pulmonology 30, no. 4 (December 2017): 232-238.

PMID
29279789
Full Text

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