John J. Strouse, MD, PhD

Associate Professor of Medicine
Associate Professor in the Department of Pediatrics
Email address john.strouse@duke.edu

My research has focused on the epidemiology, risk factors, and prevention of the pulmonary and central nervous system complications of sickle cell disease and includes retrospective and prospective cohort studies and clinical trials.  I received my Ph.D. in clinical investigation from the Johns Hopkins Bloomberg School of Public Health for a series of studies to identify predictors of cognitive function in children with sickle cell disease.  This work has expanded to the evaluation of the interaction between environment and disease in both children and adults with sickle cell disease.  My other research interests include the application of large clinical, research, and administrative databases to the study of rare hematological diseases and interventions to improve quality of and access to care for sickle cell disease. I serve on the American Society of Hematology Sickle Cell Taskforce and Sickle Cell Pain Guideline Panel and am co-chair of the American Society of Hematology Healthcare Professional Education and Training Work Group.

 

Education and Training

  • Fellow in Pediatric Hematology, Nci, National Institutes of Health, 2001 - 2004
  • Fellow in Pediatric Hematology/Oncology, Johns Hopkins University, 2001 - 2004
  • Fellow in Hematology, Nhlbi, National Institutes of Health, 2000 - 2004
  • Combined Internal Medicine/Pediatrics Residency, University of Rochester, 1996 - 2000
  • Ph.D., Johns Hopkins University, 2009
  • M.D., Johns Hopkins University School of Medicine, 1996

Publications

Pang, John, Jonathan Zelken, Amir H. Dorafshar, John J. Strouse, and Richard Redett. “Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair..” Cleft Palate Craniofac J 51, no. 6 (November 2014): 740–42. https://doi.org/10.1597/13-186.

PMID
24237226
Full Text

King, Allison A., Mark J. Rodeghier, Julie Ann Panepinto, John J. Strouse, James F. Casella, Charles T. Quinn, Michael M. Dowling, et al. “Silent cerebral infarction, income, and grade retention among students with sickle cell anemia..” Am J Hematol 89, no. 10 (October 2014): E188–92. https://doi.org/10.1002/ajh.23805.

PMID
25042018
Full Text

DeBaun, Michael R., Mae Gordon, Robert C. McKinstry, Michael J. Noetzel, Desiree A. White, Sharada A. Sarnaik, Emily R. Meier, et al. “Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia..” N Engl J Med 371, no. 8 (August 21, 2014): 699–710. https://doi.org/10.1056/NEJMoa1401731.

PMID
25140956
Full Text

Haywood, Carlton, Shawn Bediako, Sophie Lanzkron, Marie Diener-West, John Strouse, Jennifer Haythornthwaite, Gladys Onojobi, Mary Catherine Beach, and Mary Catherine IMPORT Investigators. “An unequal burden: poor patient-provider communication and sickle cell disease..” Patient Educ Couns 96, no. 2 (August 2014): 159–64. https://doi.org/10.1016/j.pec.2014.05.013.

PMID
24935607
Full Text

Burnett, Arthur L., Uzoma A. Anele, Irene N. Trueheart, John J. Strouse, and James F. Casella. “Randomized controlled trial of sildenafil for preventing recurrent ischemic priapism in sickle cell disease..” Am J Med 127, no. 7 (July 2014): 664–68. https://doi.org/10.1016/j.amjmed.2014.03.019.

PMID
24680796
Full Text

Haywood, Carlton, Sophie Lanzkron, Marie Diener-West, Jennifer Haythornthwaite, John J. Strouse, Shawn Bediako, Gladys Onojobi, Mary Catherine Beach, and Mary Catherine IMPORT Investigators. “Attitudes toward clinical trials among patients with sickle cell disease..” Clin Trials 11, no. 3 (June 2014): 275–83. https://doi.org/10.1177/1740774513519876.

PMID
24532686
Full Text

Sadreameli, Sara Christina, Megan E. Reller, David G. Bundy, James F. Casella, and John J. Strouse. “Respiratory syncytial virus and seasonal influenza cause similar illnesses in children with sickle cell disease..” Pediatr Blood Cancer 61, no. 5 (May 2014): 875–78. https://doi.org/10.1002/pbc.24887.

PMID
24481883
Full Text

Barodka, Viachaslau M., Enika Nagababu, Joy G. Mohanty, Daniel Nyhan, Dan E. Berkowitz, Joseph M. Rifkind, and John J. Strouse. “New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease..” Blood Cells Mol Dis 52, no. 4 (April 2014): 230–35. https://doi.org/10.1016/j.bcmd.2013.10.004.

PMID
24246527
Full Text

McCrory, Michael C., John J. Strouse, Clifford M. Takemoto, and R Blaine Easley. “Computerized physician order entry improves compliance with a manual exchange transfusion protocol in the pediatric intensive care unit..” J Pediatr Hematol Oncol 36, no. 2 (March 2014): 143–47. https://doi.org/10.1097/MPH.0b013e31828e55e6.

PMID
23619120
Full Text

Takemoto, Clifford M., Sajeet Sohi, Kruti Desai, Raman Bharaj, Anuj Khanna, Susan McFarland, Sybil Klaus, et al. “Hospital-associated venous thromboembolism in children: incidence and clinical characteristics..” J Pediatr 164, no. 2 (February 2014): 332–38. https://doi.org/10.1016/j.jpeds.2013.10.025.

PMID
24332452
Full Text

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