Geriatrics

Kenneth Edwin Schmader, MD

Professor of Medicine
Director of the GRECC and ACOS for Geriatrics and Extended Care
Senior Fellow in the Center for the Study of Aging and Human Development
Campus mail Duke Box 3469, Durham, NC 27710
Phone (919) 660-7572
Email address kenneth.schmader@duke.edu

Dr. Schmader’s areas of research include herpes zoster, infections, and vaccines in older adults.  He conducts translational, clinical trials and observational studies of zoster, influenza, and other infections funded by grants from the National Institute on Aging (NIA), National Institute of Allergy and Infectious Diseases (NIAID), Centers for Disease Control (CDC), VA Office of Research and Development, and Industry sources.  He has played a pivotal role in the development of zoster vaccines in older adults.  Dr. Schmader also performs research in medications and older adults, focusing on pharmacoepidemiology, optimal drug use and reduction of adverse drug reactions.

He is the Director of the NIA-funded P30 Duke Pepper Older Americans Independence Center and Co-PI of the NIAID funded Vaccine and Therapeutics Effectiveness Unit (VTEU) at Duke.  He serves on the Working Groups for the Herpes Zoster, Influenza, and General Adult Immunization Guidelines for the US Centers for Disease Control (CDC) Advisory Committee on Immunization Practices (ACIP) and is the American Geriatrics Society liaison to the ACIP.

Education and Training

  • Fellow in Geriatrics, Medicine, Duke University, 1986 - 1988
  • Chief Medical Resident, Medicine, University of Wisconsin - Madison, 1983 - 1983
  • Medical Resident, Medicine, University of Wisconsin - Madison, 1980 - 1983
  • M.D., Wake Forest University, 1980

Grants

Publications

Eshetie, Tesfahun C., Zachary A. Marcum, Kenneth E. Schmader, and Shelly L. Gray. “Medication use quality and safety in older adults: 2020 update.” J Am Geriatr Soc, December 13, 2021. https://doi.org/10.1111/jgs.17603.

PMID
34897654
Full Text

Vaughan, Monique H., Jialiang Mao, Lisa A. Karstens, Li Ma, Cindy L. Amundsen, Kenneth E. Schmader, and Nazema Y. Siddiqui. “The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections.” J Urol 206, no. 5 (November 2021): 1222–31. https://doi.org/10.1097/JU.0000000000001940.

PMID
34181466
Full Text

Whitson, Heather E., Donna Crabtree, Carl F. Pieper, Christine Ha, Sandra Au, Miles Berger, Harvey J. Cohen, et al. “A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.” J Am Geriatr Soc 69, no. 11 (November 2021): 3232–41. https://doi.org/10.1111/jgs.17384.

PMID
34325481
Full Text

Oyebanji, Oladayo A., Brigid Wilson, Debbie Keresztesy, Lenore Carias, Dennis Wilk, Michael Payne, Htin Aung, et al. “Does a lack of vaccine side effects correlate with reduced BNT162b2 mRNA vaccine response among healthcare workers and nursing home residents?” Aging Clin Exp Res 33, no. 11 (November 2021): 3151–60. https://doi.org/10.1007/s40520-021-01987-9.

PMID
34652783
Full Text

Vaughan, Monique H., Jialiang Mao, Lisa A. Karstens, Li Ma, Cindy L. Amundsen, Kenneth E. Schmader, and Nazema Y. Siddiqui. “The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections.” Journal of Urology 206, no. 5 (November 2021): 1223–31.

Scholars@Duke

Steinman, Michael A., Cynthia M. Boyd, and Kenneth E. Schmader. “Expanding Evidence for Clinical Care of Older Adults: Beyond Clinical Trial Traditions and Finding New Approaches.” Jama 326, no. 6 (August 10, 2021): 475–76. https://doi.org/10.1001/jama.2021.12134.

PMID
34292309
Full Text

Herati, Ramin Sedaghat, Luisa Victoria Silva, Laura A. Vella, Alexander Muselman, Cecile Alanio, Bertram Bengsch, Raj K. Kurupati, et al. “Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways.” Cell Rep Med 2, no. 5 (May 18, 2021): 100262. https://doi.org/10.1016/j.xcrm.2021.100262.

PMID
34095875
Full Text

Weller, Romy, Melissa K. Andrew, Joon Hyung Kim, Sean Matthews, Christophe Dessart, Myron J. Levin, Lidia Oostvogels, et al. “How does frailty impact the efficacy, reactogenicity, immunogenicity and safety of the adjuvanted recombinant zoster vaccine? A secondary analysis of the ZOE-50 and ZOE-70 studies.” In Internist, 62:168–168, 2021.

Scholars@Duke

Curran, Desmond, Joon H. Kim, Sean Matthews, Christophe Dessart, Myron J. Levin, Lidia Oostvogels, Megan E. Riley, et al. “Recombinant Zoster Vaccine Is Efficacious and Safe in Frail Individuals.” J Am Geriatr Soc 69, no. 3 (March 2021): 744–52. https://doi.org/10.1111/jgs.16917.

PMID
33197294
Full Text

Schmader, Kenneth E., Myron J. Levin, Michael Chen, Sean Matthews, Megan E. Riley, Wayne Woo, Caroline Hervé, et al. “Impact of Reactogenicity After Two Doses of Recombinant Zoster Vaccine Upon Physical Functioning and Quality of Life: An Open Phase III Trial in Older Adults.” J Gerontol a Biol Sci Med Sci 76, no. 3 (February 25, 2021): 485–90. https://doi.org/10.1093/gerona/glaa127.

PMID
32530462
Full Text

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