Kenneth Edwin Schmader, MD

Professor of Medicine
Senior Fellow in the
Chief, Division of Geriatrics in the Department of Medicine
Director, Medicine Clinical Research Unit
Interim Director of the GRECC and ACOS for Geriatrics and Extended Care
Campus mail Duke Box 3469, Durham, NC 27710
Phone (919) 660-7572
Email address schma001@mc.duke.edu

Dr. Schmader's primary area of research is herpes zoster and postherpetic neuralgia (PHN) and vaccines in older adults. He conducts pre-clinical, epidemiological and intervention studies of zoster and PHN, particularly with the zoster and influenza vaccines. He is involved with other adult vaccine development in older adults. With colleagues in the Division of Infectious Diseases, Dr. Schmader investigates other infections in older adults.

Another major research focus is adverse drug reactions, medication prescribing and pharmacoepidemiology in the elderly. The objective of the medication work is to reduce adverse drug reactions, improve inappropriate prescribing and determine drug use patterns in the elderly.

Education and Training

  • Fellow In Geriatrics, Medicine, Duke University, 1986 - 1988
  • Chief Medical Resident, Medicine, University of Wisconsin at Madison, 1983 - 1983
  • Medical Resident, Medicine, University of Wisconsin at Madison, 1980 - 1983
  • M.D., Wake Forest University, 1980

Publications

Herati, RS, Reuter, MA, Dolfi, DV, Mansfield, KD, Aung, H, Badwan, OZ, Kurupati, RK, Kannan, S, Ertl, H, Schmader, KE, Betts, MR, Canaday, DH, and Wherry, EJ. "Circulating CXCR5+PD-1+ response predicts influenza vaccine antibody responses in young adults but not elderly adults." Journal of immunology (Baltimore, Md. : 1950) 193, no. 7 (October 2014): 3528-3537.

PMID
25172499
Full Text

Halter, JB, Musi, N, McFarland Horne, F, Crandall, JP, Goldberg, A, Harkless, L, Hazzard, WR, Huang, ES, Kirkman, MS, Plutzky, J, Schmader, KE, Zieman, S, and High, KP. "Diabetes and cardiovascular disease in older adults: current status and future directions." Diabetes 63, no. 8 (August 2014): 2578-2589.

PMID
25060886
Full Text

Hurria, A, Dale, W, Mooney, M, Rowland, JH, Ballman, KV, Cohen, HJ, Muss, HB, Schilsky, RL, Ferrell, B, Extermann, M, Schmader, KE, and Mohile, SG. "Designing therapeutic clinical trials for older and frail adults with cancer: U13 conference recommendations." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 32, no. 24 (August 2014): 2587-2594. (Review)

PMID
25071116
Full Text

Uhlig, K, Leff, B, Kent, D, Dy, S, Brunnhuber, K, Burgers, JS, Greenfield, S, Guyatt, G, High, K, Leipzig, R, Mulrow, C, Schmader, K, Schunemann, H, Walter, LC, Woodcock, J, and Boyd, CM. "A Framework for Crafting Clinical Practice Guidelines that are Relevant to the Care and Management of People with Multimorbidity." Journal of General Internal Medicine 29, no. 4 (April 2014): 670-679.

Full Text

Kaye, KS, Marchaim, D, Chen, T, Baures, T, Anderson, DJ, Choi, Y, Sloane, RJ, and Schmader, KE. "Effect of nosocomial bloodstream infections on mortality, length of stay, and hospital costs in older adults." Journal of the American Geriatrics Society 62, no. 2 (February 1, 2014): 306-311.

Full Text

Kaye, KS, Marchaim, D, Chen, TY, Baures, T, Anderson, DJ, Choi, Y, Sloane, R, and Schmader, KE. "Effect of nosocomial bloodstream infections on mortality, length of stay, and hospital costs in older adults." Journal of the American Geriatrics Society 62, no. 2 (February 2014): 306-311.

PMID
24438554
Full Text

Anderson, DJ, Moehring, RW, Sloane, R, Schmader, KE, Weber, DJ, Fowler, VG, Smathers, E, and Sexton, DJ. "Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study." PloS one 9, no. 3 (2014): e91713-.

PMID
24643200
Full Text

Bridges, CB, Coyne-Beasley, T, Briere, E, Fiebelkorn, A, Grohskopf, L, Hales, C, Harpaz, R, LeBaron, C, Liang, JL, MacNeil, J, Markowitz, L, Moore, M, Pilishvili, T, Schillie, S, Strikas, RA, Williams, WW, Fryhofer, S, Harriman, K, Howell, M, Kinsinger, L, Koenigs, LP, Leger, MM, Lett, SM, Murphy, T, Palinkas, R, Poland, G, Reynolds, J, Riley, LE, Schaffner, W, Schmader, K, Temte, JL, Zimmerman, R, Peterson, D, Tan, L, and Bridges, CB. "Advisory committee on immunization practices recommended immunization schedule for adults aged 19 years or older - United States, 2014." Morbidity and Mortality Weekly Report 63, no. 5 (2014): 110-112.

Scholars@Duke

Uhlig, K, Leff, B, Kent, D, Dy, S, Brunnhuber, K, Burgers, JS, Greenfield, S, Guyatt, G, High, K, Leipzig, R, Mulrow, C, Schmader, K, Schunemann, H, Walter, LC, Woodcock, J, and Boyd, CM. "A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity." Journal of General Internal Medicine 29, no. 4 (2014): 670-679.

Full Text

Levin, MJ, Schmader, KE, Gnann, JW, McNeil, SA, Vesikari, T, Betts, RF, Keay, S, Stek, JE, Bundick, ND, Su, SC, Zhao, Y, Li, X, Chan, IS, Annunziato, PW, and Parrino, J. "Varicella-zoster virus-specific antibody responses in 50-59-year-old recipients of zoster vaccine." J Infect Dis 208, no. 9 (November 1, 2013): 1386-1390.

PMID
23908486
Full Text

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