Kimberly Lynn Blackwell, MD

Adjunct Professor in the Department of Medicine
Campus mail Duke Box 3893, Durham, NC 27710
Phone (919) 668-1748
Email address black034@mc.duke.edu

Breast cancer angiogenesis
Breast cancer in younger women
Hormonal therapy
Neoadjurant therapy for breast cancer

Current Clinical Investigations

Principal Investigator, A Phase I-II Study of Neoadjuvant Evacet/Paclitaxel/Hyperthermia in Locally Advanced Breast Cancer Patients.

Investigator, Development of Screening Markers for Breast Cancer using Circulating Immune Complexes: Collaborative Study with Diagen Medical Technologies.

Principal Investigator, Use of Plasma D-Dimer as a Predictive Marker in Colorectal Carcinoma: Correlative Science Study with Genentech, Inc.

Principal Investigator, A randomized, Phase II study of gabapentin or glutamine to prevent the peripheral neuropathy/myalgia associated with weekly taxol administration in metastatic breast and lung cancer.

Investigator, A Phase 2, Randomized, Double-Masked, Multicenter Study of Two Dose Levels of ERA-923 for the treatment of Metastatic Breast Cancer in Postmenopausal Women who have failed Tamoxifen therapy. Genetics Institute.

Investigator, A Phase I Study of Combined Doxil/Hyperthermia in Stage IV Breast Cancer.

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 1997 - 2000
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Mayo School of Health Sciences, 1994

Publications

Mouridsen, Henning T., Per Lønning, Matthias W. Beckmann, Kimberly Blackwell, Julie Doughty, Joseph Gligorov, Antonio Llombart-Cussac, Andre Robidoux, Beat Thürlimann, and Michael Gnant. “Use of aromatase inhibitors and bisphosphonates as an anticancer therapy in postmenopausal breast cancer.” Expert Rev Anticancer Ther 10, no. 11 (November 2010): 1825–36. https://doi.org/10.1586/era.10.160.

PMID
20883112
Full Text

Russell, Stuart D., Kimberly L. Blackwell, Julia Lawrence, John E. Pippen, Matthew T. Roe, Freda Wood, Virginia Paton, Eric Holmgren, and Kenneth W. Mahaffey. “Independent adjudication of symptomatic heart failure with the use of doxorubicin and cyclophosphamide followed by trastuzumab adjuvant therapy: a combined review of cardiac data from the National Surgical Adjuvant breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 clinical trials.” J Clin Oncol 28, no. 21 (July 20, 2010): 3416–21. https://doi.org/10.1200/JCO.2009.23.6950.

PMID
20530275
Full Text

Blackwell, Kimberly L., Harold J. Burstein, Anna Maria Storniolo, Hope Rugo, George Sledge, Maria Koehler, Catherine Ellis, et al. “Randomized study of Lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer.” J Clin Oncol 28, no. 7 (March 1, 2010): 1124–30. https://doi.org/10.1200/JCO.2008.21.4437.

PMID
20124187
Full Text

Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia for locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 618–24. https://doi.org/10.3109/02656736.2010.501051.

PMID
20849257
Full Text

Vujaskovic, Zeljko, Dong W. Kim, Ellen Jones, Lan Lan, Linda McCall, Mark W. Dewhirst, Oana Craciunescu, et al. “A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer.” Int J Hyperthermia 26, no. 5 (2010): 514–21. https://doi.org/10.3109/02656731003639364.

PMID
20377362
Full Text

Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data.” Int J Hyperthermia 26, no. 7 (2010): 612–17. https://doi.org/10.3109/02656736.2010.487194.

PMID
20849256
Full Text

Spector, Neil L., and Kimberly L. Blackwell. “Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancer.” J Clin Oncol 27, no. 34 (December 1, 2009): 5838–47. https://doi.org/10.1200/JCO.2009.22.1507.

PMID
19884552
Full Text

Grunberg, S. M., J. Weeks, W. F. Magnan, J. Herndon, M. L. Naughton, K. L. Blackwell, M. E. Wood, et al. “Determination of utility scores for control of chemotherapy-induced nausea or vomiting - CALGB 309801.” Journal of Supportive Oncology 7, no. 5 (December 1, 2009).

Scholars@Duke

Westmoreland, Tammy J., Sajith M. Wickramasekara, Andrew Y. Guo, Alice L. Selim, Tiffany S. Winsor, Arno L. Greenleaf, Kimberly L. Blackwell, John A. Olson, Jeffrey R. Marks, and Craig B. Bennett. “Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae.” Plos One 4, no. 6 (June 8, 2009): e5830. https://doi.org/10.1371/journal.pone.0005830.

PMID
19503795
Full Text

Pages